donepezil has been researched along with Chorea in 2 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Chorea: Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied whether donepezil improves chorea, cognition, and quality of life (QoL) in HD." | 9.12 | Effect of donepezil on motor and cognitive function in Huntington disease. ( Bernard, BA; Cubo, E; Jaglin, JA; Leurgans, SE; Shannon, KM; Tracy, D; Wuu, J, 2006) |
| " We studied whether donepezil improves chorea, cognition, and quality of life (QoL) in HD." | 5.12 | Effect of donepezil on motor and cognitive function in Huntington disease. ( Bernard, BA; Cubo, E; Jaglin, JA; Leurgans, SE; Shannon, KM; Tracy, D; Wuu, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cubo, E | 1 |
| Shannon, KM | 1 |
| Tracy, D | 1 |
| Jaglin, JA | 1 |
| Bernard, BA | 1 |
| Wuu, J | 1 |
| Leurgans, SE | 1 |
| Nozaki, I | 1 |
| Inao, G | 1 |
| Yamada, M | 1 |
1 trial available for donepezil and Chorea
| Article | Year |
|---|---|
Effect of donepezil on motor and cognitive function in Huntington disease.
Topics: Chorea; Cognition Disorders; Donepezil; Female; Humans; Huntington Disease; Indans; Male; Middle Age | 2006 |
1 other study available for donepezil and Chorea
| Article | Year |
|---|---|
Donepezil-induced chorea in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Chorea; Donepezil; Humans; In | 2007 |