donepezil has been researched along with Cerebrovascular Disorders in 8 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil has not been evaluated in Korean patients with Alzheimer's disease (AD) for up to 1 year." | 2.76 | Donepezil treatment in Alzheimer's disease patients with and without cerebrovascular lesions: a preliminary report. ( Bae, HJ; Choi, SH; Kim, BC; Kim, BK; Kim, JE; Kim, S; Kwon, JC; Lee, JS; Na, HR; Park, MY; Shim, YS; Yang, DW; Yoo, BG, 2011) |
| "Patients with vascular dementia (VaD) and Alzheimer's disease with cerebrovascular disease (AD + CVD) have dementia associated with underlying CVD." | 2.43 | Dementia with cerebrovascular disease: the benefits of early treatment. ( Schindler, RJ, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meguro, K | 1 |
| Akanuma, K | 1 |
| Meguro, M | 1 |
| Kasai, M | 1 |
| Ishii, H | 1 |
| Yamaguchi, S | 1 |
| Na, HR | 1 |
| Kim, S | 1 |
| Choi, SH | 1 |
| Yang, DW | 1 |
| Bae, HJ | 1 |
| Kim, JE | 1 |
| Park, MY | 1 |
| Shim, YS | 1 |
| Kim, BK | 1 |
| Kwon, JC | 1 |
| Yoo, BG | 1 |
| Kim, BC | 1 |
| Lee, JS | 1 |
| Amenta, F | 1 |
| Carotenuto, A | 1 |
| Fasanaro, AM | 1 |
| Rea, R | 1 |
| Traini, E | 1 |
| Frölich, L | 1 |
| Klinger, T | 1 |
| Berger, FM | 1 |
| Bowler, JV | 1 |
| Erkinjuntti, T | 1 |
| Román, G | 1 |
| Gauthier, S | 1 |
| Feldman, H | 1 |
| Rockwood, K | 1 |
| Schindler, RJ | 1 |
| Formiga, F | 1 |
| Fort, I | 1 |
| Pérez-Castejón, JM | 1 |
| Ruiz, D | 1 |
| Duaso, E | 1 |
| Riu, S | 1 |
1 review available for donepezil and Cerebrovascular Disorders
| Article | Year |
|---|---|
Dementia with cerebrovascular disease: the benefits of early treatment.
Topics: Cerebrovascular Disorders; Cholinesterase Inhibitors; Clinical Trials as Topic; Dementia, Vascular; | 2005 |
3 trials available for donepezil and Cerebrovascular Disorders
| Article | Year |
|---|---|
Donepezil treatment in Alzheimer's disease patients with and without cerebrovascular lesions: a preliminary report.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cerebrovascular Disorders; Cholinesterase Inhibit | 2011 |
The ASCOMALVA trial: association between the cholinesterase inhibitor donepezil and the cholinergic precursor choline alphoscerate in Alzheimer's disease with cerebrovascular injury: interim results.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Disorders; Donepezil; Double-Blind Metho | 2012 |
Treatment with donepezil in Alzheimer patients with and without cerebrovascular disease.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Disorders; Donepezil; Female; Ger | 2002 |
4 other studies available for donepezil and Cerebrovascular Disorders
| Article | Year |
|---|---|
Lifetime expectancy and quality-adjusted life-year in Alzheimer's disease with and without cerebrovascular disease: effects of nursing home replacement and donepezil administration--a retrospective analysis in the Tajiri Project.
Topics: Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Comorbidity; Donepezil; Hum | 2015 |
Acetylcholinesterase inhibitors for vascular dementia and Alzheimer's disease combined with cerebrovascular disease.
Topics: Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition Disorders; Dement | 2003 |
Emerging therapies for vascular dementia and vascular cognitive impairment.
Topics: Carbamates; Cardiovascular Diseases; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition | 2004 |
[Risperidone and cerebrovascular adverse effects in elderly patients with dementia].
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Cerebrovascular Disorders; Cholinesterase Inhibitors; | 2006 |