donepezil has been researched along with Cerebral Infarction, Middle Cerebral Artery in 5 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil has proven to be an effective drug to reduce neuronal death and subsequently injury in neurodegenerative diseases." | 5.62 | Donepezil attenuates injury following ischaemic stroke by stimulation of neurogenesis, angiogenesis, and inhibition of inflammation and apoptosis. ( Aboutaleb, N; Golmohammadi, S; Madani Neishaboori, A; Nasseri Maleki, S; Nazarinia, D; Saberi Pirouz, M, 2021) |
| "Donepezil has proven to be an effective drug to reduce neuronal death and subsequently injury in neurodegenerative diseases." | 1.62 | Donepezil attenuates injury following ischaemic stroke by stimulation of neurogenesis, angiogenesis, and inhibition of inflammation and apoptosis. ( Aboutaleb, N; Golmohammadi, S; Madani Neishaboori, A; Nasseri Maleki, S; Nazarinia, D; Saberi Pirouz, M, 2021) |
| "Donepezil was given orally in various regimens, prior to MCA occlusion in rats." | 1.33 | Neuroprotective effect of donepezil, a nicotinic acetylcholine-receptor activator, on cerebral infarction in rats. ( Fujiki, M; Inoue, R; Ishii, K; Kobayashi, H; Uchida, S, 2005) |
| "Left middle cerebral artery occlusion (MCAO) was performed in female Sprague-Dawley rats." | 1.33 | Acetylcholinesterase inhibitor acting on the brain improves detrusor overactivity caused by cerebral infarction in rats. ( Akino, H; Aoki, Y; Ito, H; Kaneda, T; Matsuta, Y; Miwa, Y; Nakai, M; Oyama, N; Shiyama, R; Tanase, K; Yokoyama, O, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Madani Neishaboori, A | 1 |
| Nasseri Maleki, S | 1 |
| Saberi Pirouz, M | 1 |
| Golmohammadi, S | 1 |
| Nazarinia, D | 1 |
| Aboutaleb, N | 1 |
| Yamazaki, Y | 1 |
| Harada, S | 1 |
| Tokuyama, S | 1 |
| Kim, SH | 1 |
| Chung, DK | 1 |
| Lee, YJ | 1 |
| Song, CH | 1 |
| Ku, SK | 1 |
| Fujiki, M | 1 |
| Kobayashi, H | 1 |
| Uchida, S | 1 |
| Inoue, R | 1 |
| Ishii, K | 1 |
| Nakai, M | 1 |
| Akino, H | 1 |
| Kaneda, T | 1 |
| Matsuta, Y | 1 |
| Shiyama, R | 1 |
| Tanase, K | 1 |
| Ito, H | 1 |
| Aoki, Y | 1 |
| Oyama, N | 1 |
| Miwa, Y | 1 |
| Yokoyama, O | 1 |
5 other studies available for donepezil and Cerebral Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Donepezil attenuates injury following ischaemic stroke by stimulation of neurogenesis, angiogenesis, and inhibition of inflammation and apoptosis.
Topics: Angiogenesis Inducing Agents; Animals; Apoptosis; Donepezil; Dose-Response Relationship, Drug; Infar | 2021 |
Sodium-glucose transporter type 3-mediated neuroprotective effect of acetylcholine suppresses the development of cerebral ischemic neuronal damage.
Topics: Acetylcholine; Animals; Animals, Outbred Strains; Astrocytes; Blood Glucose; Brain Ischemia; Choline | 2014 |
Neuroprotective effects of Danggui-Jakyak-San on rat stroke model through antioxidant/antiapoptotic pathway.
Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Biomarkers; Caspase 3; Cerebral Cortex; Cholines | 2016 |
Neuroprotective effect of donepezil, a nicotinic acetylcholine-receptor activator, on cerebral infarction in rats.
Topics: Animals; Donepezil; Indans; Infarction, Middle Cerebral Artery; Ischemic Preconditioning; Male; Neur | 2005 |
Acetylcholinesterase inhibitor acting on the brain improves detrusor overactivity caused by cerebral infarction in rats.
Topics: Analysis of Variance; Animals; Brain; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Donepe | 2006 |