donepezil has been researched along with Carotid Stenosis in 2 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| "After carotid stenosis was relieved, the cerebral blood flow values significantly increased, and P300 latency and escape latency in the Morris water-maze were significantly shortened." | 1.37 | Relief of carotid stenosis improves impaired cognition in a rat model of chronic cerebral hypoperfusion. ( Chen, KN; Chun-Qing, Z; Duan, W; Gui, L; Huang, HQ; Zheng, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nyitrai, G | 1 |
| Spisák, T | 1 |
| Spisák, Z | 1 |
| Gajári, D | 1 |
| Diószegi, P | 1 |
| Kincses, TZ | 1 |
| Czurkó, A | 1 |
| Duan, W | 1 |
| Chun-Qing, Z | 1 |
| Zheng, J | 1 |
| Gui, L | 1 |
| Huang, HQ | 1 |
| Chen, KN | 1 |
2 other studies available for donepezil and Carotid Stenosis
| Article | Year |
|---|---|
Stepwise occlusion of the carotid arteries of the rat: MRI assessment of the effect of donepezil and hypoperfusion-induced brain atrophy and white matter microstructural changes.
Topics: Animals; Brain Ischemia; Carotid Artery, Common; Carotid Stenosis; Cerebrovascular Circulation; Diff | 2018 |
Relief of carotid stenosis improves impaired cognition in a rat model of chronic cerebral hypoperfusion.
Topics: Acetylcholine; Acoustic Stimulation; Analysis of Variance; Animals; Biogenic Monoamines; Brain Ische | 2011 |