donepezil has been researched along with Cardiac Remodeling, Ventricular in 2 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral administration of donepezil, a centrally acting acetylcholinesterase inhibitor, improves the survival of rats with chronic heart failure (CHF)." | 7.96 | Intracerebroventricular infusion of donepezil prevents cardiac remodeling and improves the prognosis of chronic heart failure rats. ( Inagaki, M; Kawada, T; Li, M; Sugimachi, M; Uemura, K; Zheng, C, 2020) |
| "Oral administration of donepezil, a centrally acting acetylcholinesterase inhibitor, improves the survival of rats with chronic heart failure (CHF)." | 3.96 | Intracerebroventricular infusion of donepezil prevents cardiac remodeling and improves the prognosis of chronic heart failure rats. ( Inagaki, M; Kawada, T; Li, M; Sugimachi, M; Uemura, K; Zheng, C, 2020) |
| "Chronic treatment with donepezil or pyridostigmine started before the onset of hypertension." | 3.81 | Acetylcholinesterase Inhibition Attenuates the Development of Hypertension and Inflammation in Spontaneously Hypertensive Rats. ( Lataro, RM; Prado, CM; Salgado, HC; Silva, CA; Tefé-Silva, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, M | 1 |
| Zheng, C | 1 |
| Kawada, T | 1 |
| Inagaki, M | 1 |
| Uemura, K | 1 |
| Sugimachi, M | 1 |
| Lataro, RM | 1 |
| Silva, CA | 1 |
| Tefé-Silva, C | 1 |
| Prado, CM | 1 |
| Salgado, HC | 1 |
2 other studies available for donepezil and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Intracerebroventricular infusion of donepezil prevents cardiac remodeling and improves the prognosis of chronic heart failure rats.
Topics: Animals; Cholinesterase Inhibitors; Donepezil; Fibrosis; Heart Failure; Injections, Intraventricular | 2020 |
Acetylcholinesterase Inhibition Attenuates the Development of Hypertension and Inflammation in Spontaneously Hypertensive Rats.
Topics: Animals; Blood Pressure; Cholinesterase Inhibitors; Cytokines; Donepezil; Drug Evaluation, Preclinic | 2015 |