donepezil has been researched along with Brain Vascular Disorders in 8 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil has not been evaluated in Korean patients with Alzheimer's disease (AD) for up to 1 year." | 2.76 | Donepezil treatment in Alzheimer's disease patients with and without cerebrovascular lesions: a preliminary report. ( Bae, HJ; Choi, SH; Kim, BC; Kim, BK; Kim, JE; Kim, S; Kwon, JC; Lee, JS; Na, HR; Park, MY; Shim, YS; Yang, DW; Yoo, BG, 2011) |
| "Patients with vascular dementia (VaD) and Alzheimer's disease with cerebrovascular disease (AD + CVD) have dementia associated with underlying CVD." | 2.43 | Dementia with cerebrovascular disease: the benefits of early treatment. ( Schindler, RJ, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meguro, K | 1 |
| Akanuma, K | 1 |
| Meguro, M | 1 |
| Kasai, M | 1 |
| Ishii, H | 1 |
| Yamaguchi, S | 1 |
| Na, HR | 1 |
| Kim, S | 1 |
| Choi, SH | 1 |
| Yang, DW | 1 |
| Bae, HJ | 1 |
| Kim, JE | 1 |
| Park, MY | 1 |
| Shim, YS | 1 |
| Kim, BK | 1 |
| Kwon, JC | 1 |
| Yoo, BG | 1 |
| Kim, BC | 1 |
| Lee, JS | 1 |
| Amenta, F | 1 |
| Carotenuto, A | 1 |
| Fasanaro, AM | 1 |
| Rea, R | 1 |
| Traini, E | 1 |
| Frölich, L | 1 |
| Klinger, T | 1 |
| Berger, FM | 1 |
| Bowler, JV | 1 |
| Erkinjuntti, T | 1 |
| Román, G | 1 |
| Gauthier, S | 1 |
| Feldman, H | 1 |
| Rockwood, K | 1 |
| Schindler, RJ | 1 |
| Formiga, F | 1 |
| Fort, I | 1 |
| Pérez-Castejón, JM | 1 |
| Ruiz, D | 1 |
| Duaso, E | 1 |
| Riu, S | 1 |
1 review available for donepezil and Brain Vascular Disorders
| Article | Year |
|---|---|
Dementia with cerebrovascular disease: the benefits of early treatment.
Topics: Cerebrovascular Disorders; Cholinesterase Inhibitors; Clinical Trials as Topic; Dementia, Vascular; | 2005 |
3 trials available for donepezil and Brain Vascular Disorders
| Article | Year |
|---|---|
Donepezil treatment in Alzheimer's disease patients with and without cerebrovascular lesions: a preliminary report.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cerebrovascular Disorders; Cholinesterase Inhibit | 2011 |
The ASCOMALVA trial: association between the cholinesterase inhibitor donepezil and the cholinergic precursor choline alphoscerate in Alzheimer's disease with cerebrovascular injury: interim results.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Disorders; Donepezil; Double-Blind Metho | 2012 |
Treatment with donepezil in Alzheimer patients with and without cerebrovascular disease.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Disorders; Donepezil; Female; Ger | 2002 |
4 other studies available for donepezil and Brain Vascular Disorders
| Article | Year |
|---|---|
Lifetime expectancy and quality-adjusted life-year in Alzheimer's disease with and without cerebrovascular disease: effects of nursing home replacement and donepezil administration--a retrospective analysis in the Tajiri Project.
Topics: Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Comorbidity; Donepezil; Hum | 2015 |
Acetylcholinesterase inhibitors for vascular dementia and Alzheimer's disease combined with cerebrovascular disease.
Topics: Alzheimer Disease; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition Disorders; Dement | 2003 |
Emerging therapies for vascular dementia and vascular cognitive impairment.
Topics: Carbamates; Cardiovascular Diseases; Cerebrovascular Disorders; Cholinesterase Inhibitors; Cognition | 2004 |
[Risperidone and cerebrovascular adverse effects in elderly patients with dementia].
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Cerebrovascular Disorders; Cholinesterase Inhibitors; | 2006 |