donepezil has been researched along with Bradykinesia in 2 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Excerpt | Relevance | Reference |
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"3-3 mg/kg) did not induce EPS signs by itself; however, it significantly potentiated bradykinesia induction with a low dose of haloperidol (0." | 3.81 | Interaction between anti-Alzheimer and antipsychotic drugs in modulating extrapyramidal motor disorders in mice. ( Fujiwara, M; Mizuguchi, Y; Morimoto, T; Ohno, Y; Shimizu, S; Sobue, A, 2015) |
" This study evaluated the effects of pretreatment with the oral cholinesterase inhibitor and anti-Alzheimer's agent, donepezil (Aricept) on the hypokinetic, hypothermic and diarrhea-inducing effects of the irreversible long-acting cholinesterase inhibitor, diisopropylfluorophosphate (DFP) in adult Sprague-Dawley rats." | 3.73 | Anticholinesterase (DFP) toxicity antagonism by chronic donepezil: a potential nerve agent treatment. ( Davis, JM; Janowsky, DS; Overstreet, DH, 2005) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Shimizu, S | 1 |
Mizuguchi, Y | 1 |
Sobue, A | 1 |
Fujiwara, M | 1 |
Morimoto, T | 1 |
Ohno, Y | 1 |
Janowsky, DS | 1 |
Davis, JM | 1 |
Overstreet, DH | 1 |
2 other studies available for donepezil and Bradykinesia
Article | Year |
---|---|
Interaction between anti-Alzheimer and antipsychotic drugs in modulating extrapyramidal motor disorders in mice.
Topics: Alzheimer Disease; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Cholinesterase Inhibitors; | 2015 |
Anticholinesterase (DFP) toxicity antagonism by chronic donepezil: a potential nerve agent treatment.
Topics: Animals; Behavior, Animal; Body Temperature; Cholinesterase Inhibitors; Diarrhea; Donepezil; Hypokin | 2005 |