donepezil has been researched along with Blood Pressure, High in 6 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "0 years) with probable or possible VaD, according to National Institute of Neurological Disorders and Stroke-Association Internationale pour la Recherche en l'Enseignement en Neurosciences criteria, were randomized to receive donepezil 5 mg/day (n = 208), donepezil 10 mg/day (after 5 mg/day for the first 28 days) (n = 215), or placebo (n = 193) for 24 weeks." | 5.10 | Donepezil in vascular dementia: a randomized, placebo-controlled study. ( Doody, R; Helme, R; Kertesz, A; Mintzer, J; Pratt, RD; Taubman, K; Wilkinson, D, 2003) |
| "Chronic treatment with donepezil or pyridostigmine started before the onset of hypertension." | 3.81 | Acetylcholinesterase Inhibition Attenuates the Development of Hypertension and Inflammation in Spontaneously Hypertensive Rats. ( Lataro, RM; Prado, CM; Salgado, HC; Silva, CA; Tefé-Silva, C, 2015) |
| " Considering that vascular dysfunction is a crucial feature of arterial hypertension, we investigated the effects of chronic administration of acetylcholinesterase inhibitors-pyridostigmine or donepezil-on vascular reactivity of spontaneously hypertensive rats (SHR)." | 1.51 | Chronic Treatment With Acetylcholinesterase Inhibitors Attenuates Vascular Dysfunction in Spontaneously Hypertensive Rats. ( Cau, SBA; Lataro, RM; Mestriner, FL; Salgado, HC; Silva, MAB; Tostes, RCA, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cavalcante, GL | 1 |
| Ferreira, FN | 1 |
| da Silva, MTB | 1 |
| Soriano, RN | 1 |
| Filho, ALMM | 1 |
| Arcanjo, DDR | 1 |
| Sabino, JPJ | 1 |
| Lataro, RM | 2 |
| Silva, MAB | 1 |
| Mestriner, FL | 1 |
| Cau, SBA | 1 |
| Tostes, RCA | 1 |
| Salgado, HC | 2 |
| Silva, CA | 1 |
| Tefé-Silva, C | 1 |
| Prado, CM | 1 |
| Wilkinson, D | 1 |
| Doody, R | 1 |
| Helme, R | 1 |
| Taubman, K | 1 |
| Mintzer, J | 1 |
| Kertesz, A | 1 |
| Pratt, RD | 1 |
| Kouta, Y | 1 |
| Sakurai, T | 1 |
| Yokono, K | 1 |
| Martínez-Vila, E | 1 |
| Murie-Fernández, M | 1 |
| Gállego Pérez-Larraya, J | 1 |
| Irimia, P | 1 |
1 review available for donepezil and Blood Pressure, High
| Article | Year |
|---|---|
[Cognitive dysfunction and dementia associated with elderly diabetes].
Topics: Aged; Antihypertensive Agents; Brain; Cognition Disorders; Dementia; Diabetes Mellitus, Type 2; Done | 2006 |
1 trial available for donepezil and Blood Pressure, High
| Article | Year |
|---|---|
Donepezil in vascular dementia: a randomized, placebo-controlled study.
Topics: Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dementia, Vascular; Donepezil; Double-Bli | 2003 |
4 other studies available for donepezil and Blood Pressure, High
| Article | Year |
|---|---|
Acetylcholinesterase inhibition prevents alterations in cardiovascular autonomic control and gastric motility in L-NAME-induced hypertensive rats.
Topics: Acetylcholinesterase; Animals; Arterial Pressure; Autonomic Nervous System; Baroreflex; Cardiovascul | 2020 |
Chronic Treatment With Acetylcholinesterase Inhibitors Attenuates Vascular Dysfunction in Spontaneously Hypertensive Rats.
Topics: Acetylcholinesterase; Animals; Antihypertensive Agents; Arterial Pressure; Cholinesterase Inhibitors | 2019 |
Acetylcholinesterase Inhibition Attenuates the Development of Hypertension and Inflammation in Spontaneously Hypertensive Rats.
Topics: Animals; Blood Pressure; Cholinesterase Inhibitors; Cytokines; Donepezil; Drug Evaluation, Preclinic | 2015 |
Neuroprotection in vascular dementia.
Topics: Animals; Cholinesterase Inhibitors; Dementia, Vascular; Donepezil; Excitatory Amino Acid Antagonists | 2006 |