Page last updated: 2024-10-26
donepezil and Atherosclerotic Parkinsonism
donepezil has been researched along with Atherosclerotic Parkinsonism in 1 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|
| "Treatment with donepezil was sometimes associated with worse parkinsonism." | 6.69 | Donepezil for treatment of dementia with Lewy bodies: a case series of nine patients. ( MacKnight, C; Rockwood, K; Shea, C, 1998) |
| "Treatment with donepezil was sometimes associated with worse parkinsonism." | 2.69 | Donepezil for treatment of dementia with Lewy bodies: a case series of nine patients. ( MacKnight, C; Rockwood, K; Shea, C, 1998) |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|
| Shea, C | 1 |
| MacKnight, C | 1 |
| Rockwood, K | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status |
|---|
| An Open Label 24-Week, Flexible Dose Trial to Assess the Safety and Efficacy of Galantamine in Patients With Dementia With Lewy Bodies[NCT00230997] | Phase 3 | 50 participants | Interventional | 2002-12-31 | Completed |
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trials
1 trial available for donepezil and Atherosclerotic Parkinsonism