donepezil has been researched along with Astrocytosis in 1 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Also, reduction of amyloid plaque burden and gliosis in the cortex and hippocampus was assessed." | 1.46 | The proof-of-concept of ASS234: Peripherally administered ASS234 enters the central nervous system and reduces pathology in a male mouse model of Alzheimer disease. ( Fernandez, AP; Futch, HS; Herrero-Labrador, R; Marco-Contelles, J; MartÃnez-Murillo, R; Romero, A; Samadi, A; Serrano, J; Serrano, MP; Unzeta, M, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Serrano, MP | 1 |
| Herrero-Labrador, R | 1 |
| Futch, HS | 1 |
| Serrano, J | 1 |
| Romero, A | 1 |
| Fernandez, AP | 1 |
| Samadi, A | 1 |
| Unzeta, M | 1 |
| Marco-Contelles, J | 1 |
| MartÃnez-Murillo, R | 1 |
1 other study available for donepezil and Astrocytosis
| Article | Year |
|---|---|
The proof-of-concept of ASS234: Peripherally administered ASS234 enters the central nervous system and reduces pathology in a male mouse model of Alzheimer disease.
Topics: Alzheimer Disease; Animals; Cell Survival; Cerebral Cortex; Disease Models, Animal; Donepezil; Glios | 2017 |