Page last updated: 2024-10-26

donepezil and Anorexia

donepezil has been researched along with Anorexia in 5 studies

Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.

Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.

Research Excerpts

ExcerptRelevanceReference
"Donepezil, an acetylcholinesterase inhibitor, is associated with gastrointestinal symptoms, such as nausea, vomiting, and anorexia, which may affect adherence to continuous therapy."4.12Effects of Rikkunshi-To, a Japanese kampo medicine, on donepezil-induced gastrointestinal side effects in mice. ( Hagihara, K; Jotaki, A; Kirikihira, K; Michihara, A; Miyake, Y; Sato, Y; Yamamoto, K, 2022)
"While these drugs are known to induce classic cholinergic adverse events such as diarrhea, their potential to cause psychiatric adverse events has yet to be thoroughly examined."3.01Psychiatric Adverse Events of Acetylcholinesterase Inhibitors in Alzheimer's Disease and Parkinson's Dementia: Systematic Review and Meta-Analysis. ( Algharably, EEA; Bermpohl, F; Bittner, N; Brandl, EJ; Funk, CSM; Kreutz, R; Riemer, TG; Schmidt, A, 2023)
"Donepezil (Aricept) is a highly selective acetylcholinesterase inhibitors with a pharmacokinetic profile allowing once-daily dosing."2.42Donepezil (Aricept) for treatment of Alzheimer's disease and other dementing conditions. ( Geldmacher, DS, 2004)
"Donepezil is a synthetic noncovalent reversible inhibitor of acetylcholinesterase (AChE) for the treatment of mild to moderate dementia associated with Alzheimer's disease."2.40Donepezil: an anticholinesterase inhibitor for Alzheimer's disease. ( Shintani, EY; Uchida, KM, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Yamamoto, K1
Sato, Y1
Hagihara, K1
Kirikihira, K1
Jotaki, A1
Michihara, A1
Miyake, Y1
Bittner, N1
Funk, CSM1
Schmidt, A1
Bermpohl, F1
Brandl, EJ1
Algharably, EEA1
Kreutz, R1
Riemer, TG1
Umegaki, H1
Yamamoto, A1
Suzuki, Y1
Iguchi, A1
Geldmacher, DS1
Shintani, EY1
Uchida, KM1

Reviews

3 reviews available for donepezil and Anorexia

ArticleYear
Psychiatric Adverse Events of Acetylcholinesterase Inhibitors in Alzheimer's Disease and Parkinson's Dementia: Systematic Review and Meta-Analysis.
    Drugs & aging, 2023, Volume: 40, Issue:11

    Topics: Acetylcholinesterase; Alzheimer Disease; Anorexia; Cholinesterase Inhibitors; Donepezil; Galantamine

2023
Donepezil (Aricept) for treatment of Alzheimer's disease and other dementing conditions.
    Expert review of neurotherapeutics, 2004, Volume: 4, Issue:1

    Topics: Alzheimer Disease; Anorexia; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition Disorder

2004
Donepezil: an anticholinesterase inhibitor for Alzheimer's disease.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997, Dec-15, Volume: 54, Issue:24

    Topics: Aged; Alzheimer Disease; Anorexia; Cholinesterase Inhibitors; Diarrhea; Donepezil; Drug Administrati

1997

Other Studies

2 other studies available for donepezil and Anorexia

ArticleYear
Effects of Rikkunshi-To, a Japanese kampo medicine, on donepezil-induced gastrointestinal side effects in mice.
    Journal of pharmacological sciences, 2022, Volume: 150, Issue:2

    Topics: Acetylcholinesterase; Animals; Anorexia; Donepezil; Drugs, Chinese Herbal; Ghrelin; Humans; Kaolin;

2022
Responses of hypothalamo-pituitary-adrenal axis to a cholinesterase inhibitor.
    Neuroreport, 2009, Oct-07, Volume: 20, Issue:15

    Topics: Adrenocorticotropic Hormone; Animals; Anorexia; Appetite; Appetite Regulation; Cholinesterase Inhibi

2009