donepezil has been researched along with Anesthesia in 2 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil pretreatment reduced central cholinergic impairment in the aged mice and prevented learning and memory declines after anesthesia/surgery." | 1.51 | Central cholinergic neuronal degeneration promotes the development of postoperative cognitive dysfunction. ( Chen, L; Jiang, X; Su, D; Tian, J; Tian, W; Wang, X; Xu, H; Yu, W; Zhang, X, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, H | 1 |
| Chen, L | 1 |
| Zhang, X | 1 |
| Jiang, X | 1 |
| Tian, W | 1 |
| Yu, W | 1 |
| Wang, X | 1 |
| Tian, J | 1 |
| Su, D | 1 |
| Sprung, J | 1 |
| Castellani, WJ | 1 |
| Srinivasan, V | 1 |
| Udayashankar, S | 1 |
2 other studies available for donepezil and Anesthesia
| Article | Year |
|---|---|
Central cholinergic neuronal degeneration promotes the development of postoperative cognitive dysfunction.
Topics: Anesthesia; Animals; Appendectomy; Brain; Cholinergic Neurons; Cholinesterase Inhibitors; Donepezil; | 2019 |
The effects of donepezil and neostigmine in a patient with unusual pseudocholinesterase activity.
Topics: Aged; Aged, 80 and over; Anesthesia; Butyrylcholinesterase; Cholinesterase Inhibitors; Donepezil; Dr | 1998 |