donepezil has been researched along with Akinetic-Rigid Variant of Huntington Disease in 3 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied whether donepezil improves chorea, cognition, and quality of life (QoL) in HD." | 9.12 | Effect of donepezil on motor and cognitive function in Huntington disease. ( Bernard, BA; Cubo, E; Jaglin, JA; Leurgans, SE; Shannon, KM; Tracy, D; Wuu, J, 2006) |
| " We studied whether donepezil improves chorea, cognition, and quality of life (QoL) in HD." | 5.12 | Effect of donepezil on motor and cognitive function in Huntington disease. ( Bernard, BA; Cubo, E; Jaglin, JA; Leurgans, SE; Shannon, KM; Tracy, D; Wuu, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavalli, A | 1 |
| Bolognesi, ML | 1 |
| Minarini, A | 1 |
| Rosini, M | 1 |
| Tumiatti, V | 1 |
| Recanatini, M | 1 |
| Melchiorre, C | 1 |
| Cubo, E | 1 |
| Shannon, KM | 1 |
| Tracy, D | 1 |
| Jaglin, JA | 1 |
| Bernard, BA | 1 |
| Wuu, J | 1 |
| Leurgans, SE | 1 |
| Fernandez, HH | 1 |
| Friedman, JH | 1 |
| Grace, J | 1 |
| Beason-Hazen, S | 1 |
1 review available for donepezil and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Multi-target-directed ligands to combat neurodegenerative diseases.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Binding Sites; Calcium | 2008 |
2 trials available for donepezil and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Effect of donepezil on motor and cognitive function in Huntington disease.
Topics: Chorea; Cognition Disorders; Donepezil; Female; Humans; Huntington Disease; Indans; Male; Middle Age | 2006 |
Donepezil for Huntington's disease.
Topics: Adult; Aged; Cholinesterase Inhibitors; Donepezil; Female; Humans; Huntington Disease; Indans; Male; | 2000 |