donepezil has been researched along with Acute Post-Traumatic Stress Disorder in 3 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Donepezil (3 mg/kg; po) and sertraline (10 mg/kg; po) dosing was started from D-8 and continued up to D-32." | 1.62 | Development and treatment of cognitive inflexibility in sub-chronic stress-re-stress (SRS) model of PTSD. ( Krishnamurthy, S; Prajapati, SK, 2021) |
| "This sequence of dosage and symptoms suggests acetylcholinesterase inhibition was the trigger for release of these memories, which are otherwise mostly chronically repressed in this individual." | 1.38 | Case report: Post-traumatic memories triggered by donepezil in a dose-dependent pattern. ( Wolff, ML, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Prajapati, SK | 1 |
| Krishnamurthy, S | 1 |
| Wolff, ML | 1 |
| McLay, RN | 1 |
| Ho, J | 1 |
3 other studies available for donepezil and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Development and treatment of cognitive inflexibility in sub-chronic stress-re-stress (SRS) model of PTSD.
Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Cognition Disorders; Disease Models, Animal; Done | 2021 |
Case report: Post-traumatic memories triggered by donepezil in a dose-dependent pattern.
Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationsh | 2012 |
Posttraumatic stress disorder-like symptoms after treatment with acetylcholinesterase inhibitors.
Topics: Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Galantamine; Humans; Indans; Magnetic Res | 2007 |