Page last updated: 2024-10-26

domperidone and Vomiting

domperidone has been researched along with Vomiting in 142 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"In this randomized, double-blind, phase 3 study, children ages 6 months to 12 years with acute gastroenteritis randomly (1:1) received oral domperidone 0."9.30Safety and Efficacy of Low-dose Domperidone for Treating Nausea and Vomiting Due to Acute Gastroenteritis in Children. ( Appiani, C; Garces-Sanchez, M; Gupta, R; Hu, P; Leitz, G; Li, Q; Mitha, E, 2019)
"Domperidone is an antiemetic that is often prescribed for children with acute gastroenteritis in Japan."9.20Domperidone with ORT in the treatment of pediatric acute gastroenteritis in Japan: a multicenter, randomized controlled trial. ( Hinotsu, S; Kawakami, K; Kishida, K; Kita, F; Nakahata, T; Sasaki, H; Shimakawa, T; Urushihara, H; Wakazono, Y; Yamauchi, E; Yorifuji, T, 2015)
"To compare the efficacy of ondansetron and domperidone for the symptomatic treatment of vomiting in children with AG who have failed ORT."9.15Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial. ( Arrighini, A; Bertolani, P; Biban, P; Bonati, M; Clavenna, A; Da Dalt, L; Di Pietro, P; Guala, A; Maestro, A; Mannelli, F; Marchetti, F; Messi, G; Pazzaglia, A; Perri, F; Reale, A; Renna, S; Ronfani, L; Rovere, F; Tondelli, MT; Urbino, AF; Valletta, E; Vitale, A; Zangardi, T; Zanon, D, 2011)
"We investigated the usefulness of concurrent therapy of granisetron with methylprednisolone sodium for on nausea, vomiting and anorexia induced by chemotherapy, including cisplatin, in patients with oral cancer."9.07[Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin]. ( Kawashima, T; Miyata, K; Morita, N; Ohmata, T; Sakamoto, T; Wada, T, 1993)
" CMF were included in a double-blind comparative study aimed at evaluating the efficacy of 3 different drugs (methylprednisolone (MP), metoclopramide (MTC), and domperidone (DMP) in preventing chemotherapy-induced nausea and vomiting."9.06Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF. ( Ballatori, E; Basurto, C; del Favero, A; Minotti, V; Roila, F; Tonato, M, 1987)
"A prospective randomized double-blind trial comparing the butyrophenone analogue domperidone (D) and the synthetic cannabinoid nabilone (N) in the treatment of cytotoxic-induced emesis was conducted in 38 patients receiving highly emetogenic chemotherapy regimens (70% containing cisplatin)."9.06Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis. ( Fennelly, JJ; Pomeroy, M; Towers, M, 1986)
"A randomized double-blind cross-over study was performed to evaluate the possible anti-emetic effect of the partial opiate antagonist buprenorphine in comparison to domperidone in chemotherapy-induced nausea and vomiting."9.06Buprenorphine versus domperidone in chemotherapy-induced emesis: a pilot study. ( Dullemond-Westland, AC; Neijt, JP; Nortier, JW; Sitsen, JM, 1986)
"The anti-emetic effects of domperidone were evaluated under double-blind conditions in twenty-four patients with acute vomiting randomly assigned to treatment either with 10 mg i."9.05Double-blind evaluation of domperidone in acute vomiting and dyspeptic disorders. ( Agorastos, I; Goulis, G; Kaprinis, I; Zissis, NP, 1981)
"In a double-blind comparison of domperidone 10 mg, domperidone 4 mg, metoclopramide 10 mg and a placebo, 176 adult patients were given an intravenous injection of one of these substances after postoperative vomiting had occurred."9.05Postoperative vomiting treated with domperidone. A double-blind comparison with metoclopramide and a placebo. ( Boghaert, A; Carron, D; Gallant, J; Stockman, A, 1980)
"In a single-blind trial of therapy in 20 patients with idiopathic Parkinson disease, domperidone prevented nausea and vomiting induced by bromocriptine without diminishing beneficial central effects."9.05Bromocriptine and domperidone in the treatment of Parkinson disease. ( Agid, Y; Illas, A; Lhermitte, F; Quinn, N, 1981)
" We wanted to study the effects of the new antiemetic Domperidone on vomiting after either anesthesia."9.05[Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)]. ( Alon, E; Axhausen, C; Bernoulli, L; Caluori, R; Hossli, G, 1982)
"There is increased awareness about risks and benefits of using domperidone to treat gastroparesis."7.83Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016)
"A retrospective chart review was conducted of patients with nausea (N) and vomiting (V) receiving domperidone from 2009 to 2013 under an Investigational New Drug (IND) protocol."7.81Cardiovascular safety profile and clinical experience with high-dose domperidone therapy for nausea and vomiting. ( Alvarez, A; Cooper, CJ; Gomez, Y; McCallum, RW; Ortiz, A; Sarosiek, I, 2015)
"To retrospectively analyze the individual risk factors for radioactive iodine (RAI)-associated nausea and vomiting, and to examine the anti-emetic effect of ramosetron (5-hydroxytryptamine-3 receptor antagonist) in RAI therapy."7.80Moderate to severe nausea in radioactive iodine (RAI) therapy is associated with the RAI dose per body weight and was not prevented by ramosetron. ( Ando, T; Ikeoka, T; Imaizumi, M; Kawakami, A; Ueki, I; Usa, T, 2014)
") on spontaneous behaviour and the emesis and behavioural change induced by apomorphine (0."7.73Differential action of domperidone to modify emesis and behaviour induced by apomorphine in the ferret. ( Lau, AH; Ngan, MP; Rudd, JA; Yew, DT, 2005)
" In the present studies, therefore, we used Suncus murinus, a species of insectivore capable of emesis, to investigate if the vanilloid receptor agonist resiniferatoxin is capable of modeling the emesis associated with migraine."7.73Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew). ( Andrews, PL; Cheng, FH; Moreaux, B; Ngan, MP; Rudd, JA; Sam, TS; Wai, MK; Wan, C, 2005)
"Our aim was to determine whether domperidone could improve the symptoms of patients with gastroparesis, accelerate gastric emptying, and enhance quality of life."7.69The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis. ( McCallum, RW; Sarosiek, I; Soykan, I, 1997)
"Loperamide, an opiate receptor agonist, commonly used in the treatment of diarrhoea, reliably induced emesis in the ferret, when given subcutaneously."7.68The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors. ( Andrews, PL; Bhandari, P; Bingham, S, 1992)
"Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone."7.68The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting. ( Lencz, L, 1990)
" We designed a comparative controlled study of Sulpiride and Domperidone, against nausea and vomiting during cancer chemotherapy."7.67[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986)
"Having noticed psychotic traits in some patients showing incoercible vomiting due to antineoplastic drugs we have thought of establishing a therapy with lithium in the days preceding the therapeutic cycle in order to reduce the emetic events."7.67Sequential therapy with lithium in chemotherapy-induced vomiting. ( Alfano, G; Candido, A; Mango, G; Menichella, G; Rossi, P; Tartaglione, R, 1985)
"Domperidone was not effective for the symptomatic treatment of vomiting during acute gastroenteritis."6.82Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial. ( Arrighini, A; Barbi, E; Bertolani, P; Biban, P; Bonati, M; Clavenna, A; Da Dalt, L; Guala, A; Maestro, A; Marchetti, F; Mazzoni, E; Pazzaglia, A; Perri, PF; Reale, A; Renna, S; Ronfani, L; Rovere, F; Urbino, AF; Valletta, E; Vitale, A; Zangardi, T; Zanon, D, 2016)
"Cisapride was previously used in the same indication."6.74Domperidone versus cisapride in the treatment of infant regurgitation and increased acid gastro-oesophageal reflux: a pilot study. ( Advani, N; Alatas, S; Firmansyah, A; Hegar, B; Vandenplas, Y, 2009)
"At the end of the treatment period, nausea, vomiting and reflux symptoms, adverse events and a global assessment of patients' symptom control were recorded by the investigator."6.67A comparison of controlled release metoclopramide and domperidone in the treatment of nausea and vomiting. ( Miller, AJ; Patel, NH; Roy, P, 1991)
"Droperidol was significantly more effective than domperidone, metoclopramide or placebo in reducing emetic sequelae."6.66Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery. ( Madej, TH; Simpson, KH, 1986)
" High-dose metoclopramide has demonstrated efficacy in small series of patients in the treatment of cisplatin-induced vomiting."6.15Advances in anti-emetic therapy. ( Bakowski, MT, 1984)
"Domperidone is a commonly prescribed antiemetic drug but its side effects are rarely seen."5.40Domperidone-induced dystonia: a rare and troublesome complication. ( Bhandari, D; Dhakal, M; Dhakal, OP, 2014)
"In this randomized, double-blind, phase 3 study, children ages 6 months to 12 years with acute gastroenteritis randomly (1:1) received oral domperidone 0."5.30Safety and Efficacy of Low-dose Domperidone for Treating Nausea and Vomiting Due to Acute Gastroenteritis in Children. ( Appiani, C; Garces-Sanchez, M; Gupta, R; Hu, P; Leitz, G; Li, Q; Mitha, E, 2019)
"Pretreatment with domperidone inhibited apomorphine-induced kaolin intake."5.29Pica in rats is analogous to emesis: an animal model in emesis research. ( Hasegawa, S; Matsunaga, T; Morita, M; Takeda, N, 1993)
"Apomorphine induced an increase of gastrin levels which peaked at 5 min."5.27Effects of dopamine receptor antagonists on gastrin and vomiting responses to apomorphine. ( Goiny, M; Uvnäs-Moberg, K, 1987)
"Domperidone is an antiemetic that is often prescribed for children with acute gastroenteritis in Japan."5.20Domperidone with ORT in the treatment of pediatric acute gastroenteritis in Japan: a multicenter, randomized controlled trial. ( Hinotsu, S; Kawakami, K; Kishida, K; Kita, F; Nakahata, T; Sasaki, H; Shimakawa, T; Urushihara, H; Wakazono, Y; Yamauchi, E; Yorifuji, T, 2015)
"To compare the efficacy of ondansetron and domperidone for the symptomatic treatment of vomiting in children with AG who have failed ORT."5.15Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial. ( Arrighini, A; Bertolani, P; Biban, P; Bonati, M; Clavenna, A; Da Dalt, L; Di Pietro, P; Guala, A; Maestro, A; Mannelli, F; Marchetti, F; Messi, G; Pazzaglia, A; Perri, F; Reale, A; Renna, S; Ronfani, L; Rovere, F; Tondelli, MT; Urbino, AF; Valletta, E; Vitale, A; Zangardi, T; Zanon, D, 2011)
" During 5 days prior to the apomorphine all received Motilium (domperidone, 60 mg/d) to prevent nausea and vomiting."5.09[Apomorphine for treatment of "off-periods" in Parkinson's disease]. ( Kuritzky, A; Melamed, E; Merims, D; Ziv, I; Zoldan, J, 1999)
"To compare ondansetron and domperidone for treatment of delayed nausea/vomiting (DN/V) following highly emetogenic chemotherapy, after attaining total suppression of emesis on the day of chemotherapy by mean of ondansetron (combined with dexamethasone in the case of cisplatin-treated patients)."5.08Prophylaxis of delayed nausea and vomiting after cancer chemotherapy. ( Borm, JJ; Esseboom, EU; Rojer, RA; Statius van Eps, LW, 1995)
"We investigated the usefulness of concurrent therapy of granisetron with methylprednisolone sodium for on nausea, vomiting and anorexia induced by chemotherapy, including cisplatin, in patients with oral cancer."5.07[Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin]. ( Kawashima, T; Miyata, K; Morita, N; Ohmata, T; Sakamoto, T; Wada, T, 1993)
"A prospective randomized double-blind trial comparing the butyrophenone analogue domperidone (D) and the synthetic cannabinoid nabilone (N) in the treatment of cytotoxic-induced emesis was conducted in 38 patients receiving highly emetogenic chemotherapy regimens (70% containing cisplatin)."5.06Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis. ( Fennelly, JJ; Pomeroy, M; Towers, M, 1986)
" CMF were included in a double-blind comparative study aimed at evaluating the efficacy of 3 different drugs (methylprednisolone (MP), metoclopramide (MTC), and domperidone (DMP) in preventing chemotherapy-induced nausea and vomiting."5.06Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF. ( Ballatori, E; Basurto, C; del Favero, A; Minotti, V; Roila, F; Tonato, M, 1987)
"A randomized double-blind cross-over study was performed to evaluate the possible anti-emetic effect of the partial opiate antagonist buprenorphine in comparison to domperidone in chemotherapy-induced nausea and vomiting."5.06Buprenorphine versus domperidone in chemotherapy-induced emesis: a pilot study. ( Dullemond-Westland, AC; Neijt, JP; Nortier, JW; Sitsen, JM, 1986)
"In a single-blind trial of therapy in 20 patients with idiopathic Parkinson disease, domperidone prevented nausea and vomiting induced by bromocriptine without diminishing beneficial central effects."5.05Bromocriptine and domperidone in the treatment of Parkinson disease. ( Agid, Y; Illas, A; Lhermitte, F; Quinn, N, 1981)
"In a double-blind comparison of domperidone 10 mg, domperidone 4 mg, metoclopramide 10 mg and a placebo, 176 adult patients were given an intravenous injection of one of these substances after postoperative vomiting had occurred."5.05Postoperative vomiting treated with domperidone. A double-blind comparison with metoclopramide and a placebo. ( Boghaert, A; Carron, D; Gallant, J; Stockman, A, 1980)
" Ondansetron revealed the largest effect in comparison to placebo for cessation of vomiting (odds ratio = 0."5.05Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis. ( Acosta-Reyes, J; Florez, ID; Niño-Serna, LF; Veroniki, AA, 2020)
" We wanted to study the effects of the new antiemetic Domperidone on vomiting after either anesthesia."5.05[Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)]. ( Alon, E; Axhausen, C; Bernoulli, L; Caluori, R; Hossli, G, 1982)
"The anti-emetic effects of domperidone were evaluated under double-blind conditions in twenty-four patients with acute vomiting randomly assigned to treatment either with 10 mg i."5.05Double-blind evaluation of domperidone in acute vomiting and dyspeptic disorders. ( Agorastos, I; Goulis, G; Kaprinis, I; Zissis, NP, 1981)
"A search of two bibliographic databases, the European Medicines Agency (EMA) website, Micromedex, Lexicomp and reference texts was undertaken for domperidone related reports of QT prolongation, cardiac arrhythmias and/or SCD."4.91Domperidone safety: a mini-review of the science of QT prolongation and clinical implications of recent global regulatory recommendations. ( Buffery, PJ; Strother, RM, 2015)
"To evaluate the risk of QT prolongation, ventricular arrhythmias and sudden cardiac death associated with the use of oral domperidone in adults without cancer."4.91[Cardiac adverse effects of domperidone in adult patients: a systematic review]. ( Avila, A; Caraballo, L; Marzi, M; Molina, G; Piskulic, L; Weitz, D, 2015)
"In patients with advanced cancer not being treated with chemotherapy or radiation therapy, metoclopramide can be used to reduce nausea and vomiting."4.88[Treatment of nausea and vomiting with prokinetics and neuroleptics in palliative care patients : a review]. ( Alt-Epping, B; Benze, G; Geyer, A; Nauck, F, 2012)
"To review the pharmacology, pharmacokinetics, efficacy, and safety of domperidone in the treatment of gastrointestinal motility disorders and emesis."4.80Domperidone: a peripherally acting dopamine2-receptor antagonist. ( Barone, JA, 1999)
"Risk-minimization measures (RMM), including label revisions were implemented in Europe for domperidone because of evidence of increased incidence of cardiac arrhythmia and sudden cardiac death."3.91Awareness of, and Compliance with, Domperidone Revised Labeling After a Risk-Minimization Activity in Europe. ( Fife, D; Hu, P; Kaplan, S; Oliveria, SA; Phillips, S; Richarz, U; Waller, J, 2019)
"Domperidone is a dopamine antagonist used for the symptomatic management of nausea and vomiting."3.91Impact of Safety Warning on Domperidone Prescribing for Geriatric Patients in South Korea: Analysis of National Insurance Claim Data. ( Han, N; Oh, JM; Rhew, K, 2019)
"There is increased awareness about risks and benefits of using domperidone to treat gastroparesis."3.83Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016)
"A retrospective chart review was conducted of patients with nausea (N) and vomiting (V) receiving domperidone from 2009 to 2013 under an Investigational New Drug (IND) protocol."3.81Cardiovascular safety profile and clinical experience with high-dose domperidone therapy for nausea and vomiting. ( Alvarez, A; Cooper, CJ; Gomez, Y; McCallum, RW; Ortiz, A; Sarosiek, I, 2015)
"To retrospectively analyze the individual risk factors for radioactive iodine (RAI)-associated nausea and vomiting, and to examine the anti-emetic effect of ramosetron (5-hydroxytryptamine-3 receptor antagonist) in RAI therapy."3.80Moderate to severe nausea in radioactive iodine (RAI) therapy is associated with the RAI dose per body weight and was not prevented by ramosetron. ( Ando, T; Ikeoka, T; Imaizumi, M; Kawakami, A; Ueki, I; Usa, T, 2014)
"Domperidone is a dopamine antagonist that has recently been released in Canada."3.76Domperidone, a new dopamine antagonist. ( Champion, MC; Hartnett, M; Yen, M, 1986)
" We performed retrospective study that examined the efficacy of preventive treatment (granisetron+dexamethasone+domperidone) for delayed emesis induced by FOLFOX4 chemotherapy for advanced and recurrent colorectal cancer."3.75[Efficacy of preventive treatment for delayed emesis induced by FOLFOX4 chemotherapy]. ( Hama, T; Hatake, K; Imada, H; Kamisugi, K; Kawakami, K; Matsusaka, S; Mizunuma, N; Nakamoto, E; Shinozaki, E; Shirai, T; Shouji, D; Suenaga, M; Suzuki, W; Takahashi, G; Yokokawa, T, 2009)
" In the present studies, therefore, we used Suncus murinus, a species of insectivore capable of emesis, to investigate if the vanilloid receptor agonist resiniferatoxin is capable of modeling the emesis associated with migraine."3.73Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew). ( Andrews, PL; Cheng, FH; Moreaux, B; Ngan, MP; Rudd, JA; Sam, TS; Wai, MK; Wan, C, 2005)
") on spontaneous behaviour and the emesis and behavioural change induced by apomorphine (0."3.73Differential action of domperidone to modify emesis and behaviour induced by apomorphine in the ferret. ( Lau, AH; Ngan, MP; Rudd, JA; Yew, DT, 2005)
"Antiemetic effect and safety of concurrent administration of ondansetron and other antiemetics (dexamethasone, domperidone and ethyl loflazepate), given for complete suppression of nausea/vomiting, were examined in 46 patients (109 courses) with gynecological cancer receiving single high-dose of cisplatin or carboplatin."3.69[Multi-drug antiemetic treatment and effect of treatment duration of concurrent steroids--for complete control of chemotherapy-induced nausea/vomiting in gynecological cancer]. ( Fujii, T; Kioka, H; Naito, H; Nakata, N; Sawasaki, T; Shigemasa, K; Shiroyama, Y; Tanimoto, H, 1997)
"Our aim was to determine whether domperidone could improve the symptoms of patients with gastroparesis, accelerate gastric emptying, and enhance quality of life."3.69The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis. ( McCallum, RW; Sarosiek, I; Soykan, I, 1997)
"Loperamide, an opiate receptor agonist, commonly used in the treatment of diarrhoea, reliably induced emesis in the ferret, when given subcutaneously."3.68The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors. ( Andrews, PL; Bhandari, P; Bingham, S, 1992)
"Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone."3.68The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting. ( Lencz, L, 1990)
"Intramuscular injection of xylazine induced dose-dependent vomiting in cats (ED50 = 0."3.67Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats. ( Hikasa, Y; Ogasawara, S; Takase, K, 1989)
"The incidence of dyspepsias and emesis occurring either as accompanying symptoms of gynaecological operations or as independent clinical conditions, therapeutic means for controlling these conditions and the mechanism of action and clinical usefulness of the dopamine antagonist domperidone have been discussed."3.67Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting. ( Sásdi, A, 1989)
" We designed a comparative controlled study of Sulpiride and Domperidone, against nausea and vomiting during cancer chemotherapy."3.67[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986)
"A dose-finding multicenter study was undertaken to evaluate the antiemetic efficacy of domperidone, an antidopaminergic drug, which has been proposed as a suitable alternative to high-dose metoclopramide in the control of cisplatin-induced nausea and vomiting."3.67A pilot study of high-dose domperidone as an antiemetic in patients treated with cisplatin. ( del Favero, A; Franzosi, MG; Pampallona, S; Roila, F; Tognoni, G; Tonato, M, 1985)
"Having noticed psychotic traits in some patients showing incoercible vomiting due to antineoplastic drugs we have thought of establishing a therapy with lithium in the days preceding the therapeutic cycle in order to reduce the emetic events."3.67Sequential therapy with lithium in chemotherapy-induced vomiting. ( Alfano, G; Candido, A; Mango, G; Menichella, G; Rossi, P; Tartaglione, R, 1985)
"The antiemetic effect of domperidone against nausea, vomiting, and anorexia induced by antineoplastic agents was compared with that of chlorpromazine."3.66[Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine]. ( Araki, Y; Seita, M; Tamura, K, 1983)
"Domperidone is a peripheral dopamine-2 receptor antagonist with prokinetic and antiemetic properties."3.01Drugs in Focus: Domperidone. ( Assa, A; Benninga, M; Borrelli, O; Broekaert, IJ; Carpi, FJM; Deganello Saccomani, M; Dolinsek, J; Homan, M; Mas, E; Miele, E; Puoti, MG; Thomson, M; Tzivinikos, C, 2023)
"Domperidone was not effective for the symptomatic treatment of vomiting during acute gastroenteritis."2.82Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial. ( Arrighini, A; Barbi, E; Bertolani, P; Biban, P; Bonati, M; Clavenna, A; Da Dalt, L; Guala, A; Maestro, A; Marchetti, F; Mazzoni, E; Pazzaglia, A; Perri, PF; Reale, A; Renna, S; Ronfani, L; Rovere, F; Urbino, AF; Valletta, E; Vitale, A; Zangardi, T; Zanon, D, 2016)
"A recently developed oral serotonergic challenge test consisting of 5-Hydroxytryptophane (5-HTP, 200 mg) combined with carbidopa (CBD, 100 mg + 50 mg) exhibited dose-related neuroendocrine responsiveness and predictable pharmacokinetics."2.75Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron. ( de Kam, ML; Derijk, RH; Jacobs, GE; Kamerling, IM; van Gerven, JM; van Pelt, J; Zitman, FG, 2010)
"Cisapride was previously used in the same indication."2.74Domperidone versus cisapride in the treatment of infant regurgitation and increased acid gastro-oesophageal reflux: a pilot study. ( Advani, N; Alatas, S; Firmansyah, A; Hegar, B; Vandenplas, Y, 2009)
"At the end of the treatment period, nausea, vomiting and reflux symptoms, adverse events and a global assessment of patients' symptom control were recorded by the investigator."2.67A comparison of controlled release metoclopramide and domperidone in the treatment of nausea and vomiting. ( Miller, AJ; Patel, NH; Roy, P, 1991)
"Droperidol was significantly more effective than domperidone, metoclopramide or placebo in reducing emetic sequelae."2.66Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery. ( Madej, TH; Simpson, KH, 1986)
"Functional vomiting is rare and presents with more frequent vomiting episodes."2.44Functional nausea and vomiting. ( Talley, NJ, 2007)
"Domperidone is a dopamine-2 receptor antagonist."2.44Domperidone: review of pharmacology and clinical applications in gastroenterology. ( McCallum, RW; Reddymasu, SC; Soykan, I, 2007)
"Nausea and vomiting are common symptoms of migraine, which can be controlled with a variety of anti-emetics including phenothiazines and antihistamines."2.41Anti-emetics. ( MacGregor, EA, 2001)
"Domperidone is a commonly prescribed antiemetic drug but its side effects are rarely seen."1.40Domperidone-induced dystonia: a rare and troublesome complication. ( Bhandari, D; Dhakal, M; Dhakal, OP, 2014)
"Antiemetics are not included for treatment of vomiting associated with acute gastroenteritis (AGE) in children by standard guidelines."1.33Antiemetics for children with gastroenteritis: off-label but still on in clinical practice. ( Albano, F; Bruzzese, E; De Marco, G; Spagnuolo, MI, 2006)
" A next group of 87 patients received 60 mg/kg nicotinamide in combination with domperidone."1.31Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy. ( Bussink, J; Folkes, LK; Kaanders, JH; Stratford, MR; van der Kogel, AJ, 2002)
"Domperidone did not inhibit these cytotoxic agents-induced emeses."1.29The effects of orally administered Y-25130, a selective serotonin3-receptor antagonist, on chemotherapeutic agent-induced emesis. ( Fukuda, T; Haga, K; Inaba, K; Morimoto, Y; Setoguchi, M; Shoji, H, 1993)
"Pretreatment with domperidone inhibited apomorphine-induced kaolin intake."1.29Pica in rats is analogous to emesis: an animal model in emesis research. ( Hasegawa, S; Matsunaga, T; Morita, M; Takeda, N, 1993)
"Vomiting was secondary to an obstruction in the antrum of the stomach caused by a mass consisting of alginate."1.27Increased vomiting induced by an antiemetic drug. ( Degenhart, HJ; den Ouden, WJ; Luyendijk, I; Sinaasappel, M, 1984)
"Domperidone is an effective antiemetic for children receiving cytotoxic therapy."1.27Continuous ECG monitoring of children with cancer receiving domperidone. ( Campbell, RW; Craft, AW; Hunter, AS; Nobbs, J; Pritchard-Jones, K; Ratcliffe, JM, 1986)
"The emetic and catalepsy-inducing actions of buflomedil were studied in dog and mice."1.27[Emetic and catalepsy-inducing actions of buflomedil]. ( Hashimoto, T; Koda, H; Kuriyama, K, 1988)
"Domperidone pretreatment prevented radiation-induced emesis in all of four dogs tested."1.27Radiation-induced emesis in the dog: effects of lesions and drugs. ( Briggs, DB; Carpenter, DO; Knox, AP; Strominger, NL, 1986)
"Apomorphine was about 30 times more potent in inducing gastric relaxation when applied intracerebroventricularly (i."1.27Influence of peripheral and central administration of apomorphine and morphine on intragastric pressure in the dog. ( Blancquaert, JP; Lefebvre, RA; Willems, JL, 1985)
"Domperidone was given twice a day for one week."1.27[Effect of combined use of adrenocortical hormones and domperidone as anti-emetics during cisplatin therapy]. ( Hirose, Y; Matsushita, T; Mise, K; Nakanishi, M; Shirosaki, H; Tanaka, T; Yamaoto, T, 1985)
"Apomorphine induced an increase of gastrin levels which peaked at 5 min."1.27Effects of dopamine receptor antagonists on gastrin and vomiting responses to apomorphine. ( Goiny, M; Uvnäs-Moberg, K, 1987)

Research

Studies (142)

TimeframeStudies, this research(%)All Research%
pre-199082 (57.75)18.7374
1990's19 (13.38)18.2507
2000's12 (8.45)29.6817
2010's26 (18.31)24.3611
2020's3 (2.11)2.80

Authors

AuthorsStudies
Puoti, MG1
Assa, A1
Benninga, M1
Broekaert, IJ1
Carpi, FJM1
Deganello Saccomani, M1
Dolinsek, J1
Homan, M1
Mas, E1
Miele, E1
Tzivinikos, C1
Thomson, M1
Borrelli, O1
Rhew, K1
Han, N1
Oh, JM1
Niño-Serna, LF1
Acosta-Reyes, J1
Veroniki, AA1
Florez, ID1
Yan, XJ1
Xu, P1
Qiu, HY1
Wang, B2
Luo, QQ1
Chen, SL1
Giusti, R1
Mazzotta, M1
Filetti, M1
Daniele, G1
Tsukuura, H2
Ficorella, C1
Porzio, G1
Marchetti, P1
Verna, L1
Leitz, G1
Hu, P2
Appiani, C1
Li, Q1
Mitha, E1
Garces-Sanchez, M1
Gupta, R1
Di Lorenzo, C1
Nurko, S1
Fife, D1
Waller, J1
Kaplan, S1
Phillips, S1
Oliveria, SA1
Richarz, U1
Ikeoka, T1
Ando, T1
Imaizumi, M1
Ueki, I1
Usa, T1
Kawakami, A1
Ramos, L1
Alarcón, O1
Adrian, Z1
Gimeno-García, AZ1
Nicolás-Pérez, D1
Jiménez-Sosa, A1
Quintero, E1
Dhakal, OP1
Dhakal, M1
Bhandari, D1
Zhang, XF1
Yin, GZ1
Liu, QG1
Liu, XM1
Yu, L1
Liu, SN1
Cui, HY1
Lv, Y1
Furyk, JS1
Meek, R1
McKenzie, S1
Ortiz, A1
Cooper, CJ1
Alvarez, A1
Gomez, Y1
Sarosiek, I2
McCallum, RW4
Marzi, M1
Weitz, D1
Avila, A1
Molina, G1
Caraballo, L1
Piskulic, L1
Buffery, PJ1
Strother, RM1
Ando, Y1
Gyawali, B1
Matsumoto, M1
Sugishita, M1
Honda, K1
Urakawa, H1
Maeda, O1
Hasegawa, Y1
Smith, LA1
Azariah, F1
Lavender, VT1
Stoner, NS1
Bettiol, S1
Lewis, K1
Alqahtani, Z1
Mcintyre, L1
Almenawer, S1
Alshamsi, F1
Rhodes, A1
Evans, L1
Angus, DC1
Alhazzani, W1
Schey, R1
Saadi, M1
Midani, D1
Roberts, AC1
Parupalli, R1
Parkman, HP1
Marchetti, F2
Bonati, M2
Maestro, A2
Zanon, D2
Rovere, F2
Arrighini, A2
Barbi, E1
Bertolani, P2
Biban, P2
Da Dalt, L2
Guala, A2
Mazzoni, E1
Pazzaglia, A2
Perri, PF1
Reale, A2
Renna, S2
Urbino, AF2
Valletta, E2
Vitale, A2
Zangardi, T2
Clavenna, A2
Ronfani, L2
Jacobs, GE1
Kamerling, IM1
de Kam, ML1
Derijk, RH1
van Pelt, J1
Zitman, FG1
van Gerven, JM1
Hegar, B1
Alatas, S1
Advani, N1
Firmansyah, A1
Vandenplas, Y1
Yokokawa, T1
Matsusaka, S1
Shouji, D1
Imada, H1
Nakamoto, E1
Kamisugi, K1
Suzuki, W1
Shirai, T1
Takahashi, G1
Kawakami, K3
Shinozaki, E1
Suenaga, M1
Mizunuma, N1
Hatake, K1
Hama, T1
Di Pietro, P1
Mannelli, F1
Messi, G1
Perri, F1
Tondelli, MT1
Festin, M1
Kita, F1
Hinotsu, S1
Yorifuji, T1
Urushihara, H1
Shimakawa, T1
Kishida, K1
Wakazono, Y1
Yamauchi, E1
Sasaki, H1
Nakahata, T1
Pinto, TF1
Rocha, R1
Paula, CA1
de Jesus, RP1
Pozzi, M1
Strazzer, S1
Locatelli, F1
Galbiati, S1
Formica, F1
Maestri, L1
Clementi, E1
Radice, S1
Scott, B1
Benze, G1
Alt-Epping, B1
Geyer, A1
Nauck, F1
Segula, D1
Mwandiambira, V1
Howson, W1
Allain, TJ1
Bussink, J1
Stratford, MR1
van der Kogel, AJ1
Folkes, LK1
Kaanders, JH1
MacGregor, EA1
Cheng, FH1
Andrews, PL2
Moreaux, B1
Ngan, MP2
Rudd, JA2
Sam, TS1
Wai, MK1
Wan, C1
Lau, AH1
Yew, DT1
Albano, F1
Bruzzese, E1
Spagnuolo, MI1
De Marco, G1
Reddymasu, SC1
Soykan, I2
Talley, NJ1
Robinson, P1
Bakowski, MT1
Joss, RA1
Goldhirsch, A1
Brunner, KW1
Galeazzi, RL1
van der Steen, M1
Du Caju, MV1
Van Acker, KJ1
Casteels-Van Daele, M1
Dobosz-Cyklis, R1
Van de Casseye, W1
Verbeeck, P1
Wijndaele, L1
Palazzo, MG1
Strunin, L1
Giaccone, G1
Bertetto, O1
Calciati, A1
Di Paolo, N1
De Mia, M1
Gaggiotti, E1
Baggerman, C1
Sinaasappel, M1
den Ouden, WJ1
Luyendijk, I1
Degenhart, HJ1
Guldager, H1
Jensen, FM1
Andersen, KH1
Arnfred, I1
Clarke, RS1
Dubois, A2
Jacobus, JP1
Grissom, MP1
Eng, RR2
Conklin, JJ2
Spelina, KR1
Gerber, HR1
Pagels, IL1
Valenzuela, JE1
Dooley, CP1
Weaving, A1
Bezwoda, WR1
Derman, DP1
Roussak, JB1
Carey, P1
Parry, H1
Usui, N1
Ogawa, K1
Inagaki, J1
Horikoshi, N1
Inoue, T1
Urabe, A1
Saito, T2
Takaku, F1
Araki, Y1
Tamura, K1
Seita, M1
Warde, P1
Cantwell, B1
Fennelly, J1
Powderly, W1
Conroy, R1
Ise, T1
Ohira, M1
Omiya, A1
Hirose, M1
Shibata, T1
Boghaert, A1
Carron, D1
Gallant, J1
Stockman, A1
van Leeuwen, L2
Helmers, JH2
Agorastos, I1
Zissis, NP1
Kaprinis, I1
Goulis, G1
Caruso, U1
D'Iddio, S1
Cravotto, E1
Pesce, S1
Betti, I1
Ruscitto, G1
Ecari, U1
Sabrie, AM1
Minobe, T1
Sekine, H1
Torii, T1
Fujiya, T1
Ohtomo, Y1
Alon, E1
Caluori, R1
Bernoulli, L1
Axhausen, C1
Hossli, G1
Tauber, A1
Eschar, J1
Labatto, S1
van den Broek, PJ1
Henny, FC1
van Dijk, JG1
Bogaert, M1
Quinn, N1
Illas, A1
Lhermitte, F1
Agid, Y1
Gnauen, H1
Esseboom, EU1
Rojer, RA1
Borm, JJ1
Statius van Eps, LW1
Olver, IN1
Laidlaw, CR1
Matthews, JP1
Bishop, JF1
Hayes, AM1
Wolf, M1
Toner, GC1
Haga, K1
Inaba, K1
Shoji, H1
Morimoto, Y1
Fukuda, T1
Setoguchi, M1
Kawashima, T1
Wada, T1
Morita, N1
Ohmata, T1
Miyata, K1
Sakamoto, T1
Carella, G1
Marra, L1
Takeda, N1
Hasegawa, S1
Morita, M1
Matsunaga, T1
Iwanaga, Y1
Miyashita, N1
Morikawa, K1
Itoh, Z1
Rampello, L1
Raffaele, R1
Nicoletti, G1
Le Pira, F1
Vecchio, I1
Malaguarnera, M1
Drago, F1
Fujii, T1
Nakata, N1
Shiroyama, Y1
Sawasaki, T1
Tanimoto, H1
Shigemasa, K1
Kioka, H1
Naito, H1
Barone, JA1
Zoldan, J1
Merims, D1
Kuritzky, A1
Ziv, I1
Melamed, E1
Lefebvre, RA2
Willems, JL2
Bhandari, P1
Bingham, S1
Polubiec, A1
Krasnopolska-Polanczky, Z1
Duda-Król, W1
Jórasz, I1
Witkowski, J1
Varga, A1
Lovas, J1
Roy, P1
Patel, NH1
Miller, AJ1
Bonuccelli, U1
Nocchiero, A1
Napolitano, A1
Paoletti, AM1
Melis, GB1
Corsini, GU1
Muratorio, A1
Lencz, L1
Williams, CJ1
Davies, C1
Raval, M1
Middleton, J1
Luken, J1
Stone, B1
Lang, IM1
Marvig, J1
Hikasa, Y1
Takase, K1
Ogasawara, S1
Sásdi, A1
Cherian, S1
Sachdev, HP1
Puri, RK1
Dodds, LJ1
Osborne, RJ1
Slevin, ML1
Hunter, RW1
Hamer, J1
Goiny, M1
Uvnäs-Moberg, K1
Madej, TH2
Simpson, KH2
Murakami, M1
Ota, K1
Dalzell, AM1
Bartlett, H1
Lilleyman, JS1
Pomeroy, M1
Fennelly, JJ1
Towers, M1
Champion, MC2
Ratcliffe, JM1
Nobbs, J1
Campbell, RW1
Hunter, AS1
Pritchard-Jones, K1
Craft, AW1
Danquechin Dorval, E1
Mueller, GP1
Durakovic, A1
Carpenter, DO2
Briggs, DB2
Strominger, NL2
Fister, T1
Wilson, S1
Takács, G1
Porkoláb, E1
Koda, H1
Hashimoto, T1
Kuriyama, K1
Udvardi, G1
Roila, F2
Tonato, M2
Basurto, C1
Minotti, V1
Ballatori, E1
del Favero, A2
Miner, WD1
Sanger, GJ1
Turner, DH1
Fabri, M1
Nazzicone, Q1
Galanti, A1
Maselli, G1
King, GL1
Horváth, I1
Dullemond-Westland, AC1
Neijt, JP1
Nortier, JW1
Sitsen, JM1
Hartnett, M1
Yen, M1
Nappi, C1
Colace, G1
Di Renzo, GF1
Taglialatela, M1
Amoroso, S1
Annunziato, L1
Montemagno, U1
Cordts, RE1
Yochmowitz, MG1
Hardy, KA1
Shafrir, Y1
Levy, Y1
Steinherz, R1
Sakata, Y1
Suzuki, H1
Satoh, T1
Kawatsu, S1
Tanabe, K1
Okamoto, K1
Takagi, S1
Komatsu, Y1
Yoshida, Y1
Knox, AP1
Biasini, A1
Alberti, A1
Waldmann, CS1
Verghese, C1
Short, SM1
Goldhill, DR1
Evans, SJ1
Huys, J1
Troch, M1
Bourguignon, RP1
Smets, P1
Shinkai, T1
Saijo, N1
Sawamura, N1
Funaki, U1
Takahashi, S1
Yokoyama, S1
Fujita, J1
Futami, H1
Sasaki, Y1
Shimizu, E1
Critchley, P1
Langdon, N1
Parkes, JD1
Quinn, NP1
Shindler, JS1
Marsden, CD1
Lee, KY1
Park, HJ1
Chey, WY1
Blancquaert, JP1
Tanaka, T1
Nakanishi, M1
Hirose, Y1
Mise, K1
Matsushita, T1
Yamaoto, T1
Shirosaki, H1
Tognoni, G1
Franzosi, MG1
Pampallona, S1
Candido, A1
Rossi, P1
Tartaglione, R1
Alfano, G1
Menichella, G1
Mango, G1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group, Prospective Study to Evaluate the Safety and Efficacy of Domperidone in 6-month-old to 12-year-old Pediatric Subjects With Nausea and Vomiting Due to Acute Gastroenteritis[NCT02699385]Phase 310 participants (Actual)Interventional2015-12-07Terminated (stopped due to Study prematurely terminated upon recommendation of IDMC due to lack of efficacy.)
Oral Ondansetron vs Domperidone for Symptomatic Treatment of Vomiting During Acute Gastroenteritis in Children: Multicentre Randomized Controlled Trial[NCT01257672]Phase 3356 participants (Actual)Interventional2011-07-31Completed
An Investigational New Drug Program for the Use of Domperidone in the Treatment of Refractory Gastroesophageal Reflux Disease and Other Gastrointestinal Motility Disorders[NCT00777439]75 participants (Anticipated)Interventional2008-10-31Recruiting
Oral Domperidone for Relief of Gastrointestinal Disorders in Patients Who Failed Standard Therapy[NCT00761254]42 participants (Actual)Interventional2008-08-31Terminated (stopped due to PI withdrew due to increased responsibilities in clinical department.)
Does Domperidone, a D2-antagonist Alter Gastric Emptying Rates and Appetite Sensations in Healthy Adults?[NCT01347814]13 participants (Actual)Interventional2008-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

24 reviews available for domperidone and Vomiting

ArticleYear
Drugs in Focus: Domperidone.
    Journal of pediatric gastroenterology and nutrition, 2023, 08-01, Volume: 77, Issue:2

    Topics: Antiemetics; Child; Domperidone; Gastrointestinal Agents; Gastrointestinal Diseases; Humans; Infant;

2023
Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis.
    Pediatrics, 2020, Volume: 145, Issue:4

    Topics: Acute Disease; Antiemetics; Child; Child, Preschool; Dexamethasone; Diarrhea; Dimenhydrinate; Domper

2020
[Cardiac adverse effects of domperidone in adult patients: a systematic review].
    Revista medica de Chile, 2015, Volume: 143, Issue:1

    Topics: Adult; Antiemetics; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Domperidone; Female; Gastroesophag

2015
Domperidone safety: a mini-review of the science of QT prolongation and clinical implications of recent global regulatory recommendations.
    The New Zealand medical journal, 2015, Jun-12, Volume: 128, Issue:1416

    Topics: Antiemetics; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Death, Sudde

2015
Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy.
    The Cochrane database of systematic reviews, 2015, Nov-12, Issue:11

    Topics: Adult; Antiemetics; Antineoplastic Agents; Cannabinoids; Chlorpromazine; Dizziness; Domperidone; Eup

2015
The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials.
    Critical care (London, England), 2016, Aug-15, Volume: 20, Issue:1

    Topics: Chi-Square Distribution; Critical Illness; Diarrhea; Domperidone; Dopamine Antagonists; Enteral Nutr

2016
Nausea and vomiting in early pregnancy.
    BMJ clinical evidence, 2009, Jun-03, Volume: 2009

    Topics: Acupressure; Administration, Oral; Domperidone; Female; Humans; Metoclopramide; Nausea; Phytotherapy

2009
Question 2. How effective is domperidone at reducing symptoms of gastro-oesophageal reflux in infants?
    Archives of disease in childhood, 2012, Volume: 97, Issue:8

    Topics: Antiemetics; Domperidone; Evidence-Based Medicine; Gastroesophageal Reflux; Humans; Infant; Male; Pa

2012
[Treatment of nausea and vomiting with prokinetics and neuroleptics in palliative care patients : a review].
    Schmerz (Berlin, Germany), 2012, Volume: 26, Issue:5

    Topics: Antiemetics; Antipsychotic Agents; Chronic Disease; Domperidone; Dopamine Antagonists; Drug Therapy,

2012
Anti-emetics.
    Current medical research and opinion, 2001, Volume: 17 Suppl 1

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Humans; Metoclopramide; Migraine Disorders; Nausea;

2001
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Functional nausea and vomiting.
    Australian family physician, 2007, Volume: 36, Issue:9

    Topics: Acute Disease; Antidepressive Agents, Tricyclic; Antiemetics; Chronic Disease; Diagnosis, Differenti

2007
Advances in anti-emetic therapy.
    Cancer treatment reviews, 1984, Volume: 11, Issue:3

    Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Clinical Trials as Topic; Dexamethasone; Do

1984
Anaesthesia and emesis. II: Prevention and management.
    Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:4

    Topics: Anesthesia; Antiemetics; Butyrophenones; Domperidone; Histamine H1 Antagonists; Humans; Metocloprami

1984
Nausea and vomiting.
    British journal of anaesthesia, 1984, Volume: 56, Issue:1

    Topics: Analgesics; Anesthetics; Domperidone; Humans; Metoclopramide; Nausea; Phenothiazines; Piperazines; S

1984
Dopamine antagonists in the upper gastrointestinal tract.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 96

    Topics: Diabetic Neuropathies; Digestive System; Domperidone; Dopamine Antagonists; Duodenum; Dyspepsia; Eso

1984
Domperidone: a peripherally acting dopamine2-receptor antagonist.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:4

    Topics: Animals; Data Collection; Diabetes Mellitus; Domperidone; Dopamine Antagonists; Drug Interactions; G

1999
Domperidone: a peripherally acting dopamine2-receptor antagonist.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:4

    Topics: Animals; Data Collection; Diabetes Mellitus; Domperidone; Dopamine Antagonists; Drug Interactions; G

1999
Domperidone: a peripherally acting dopamine2-receptor antagonist.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:4

    Topics: Animals; Data Collection; Diabetes Mellitus; Domperidone; Dopamine Antagonists; Drug Interactions; G

1999
Domperidone: a peripherally acting dopamine2-receptor antagonist.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:4

    Topics: Animals; Data Collection; Diabetes Mellitus; Domperidone; Dopamine Antagonists; Drug Interactions; G

1999
Domperidone-induced acute dystonia and polycystic ovary syndrome.
    Movement disorders : official journal of the Movement Disorder Society, 1991, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Domperidone; Dyskinesia, Drug-Induced; Dystonia; Estrogens; Female; Humans; Nause

1991
Domperidone.
    Indian pediatrics, 1989, Volume: 26, Issue:9

    Topics: Child; Child, Preschool; Domperidone; Gastric Emptying; Humans; Nausea; Vomiting

1989
The control of cancer chemotherapy-induced nausea and vomiting.
    Journal of clinical and hospital pharmacy, 1985, Volume: 10, Issue:2

    Topics: Adrenal Cortex Hormones; Anti-Anxiety Agents; Antiemetics; Antineoplastic Agents; Antipsychotic Agen

1985
[Recent advances in the management of chemotherapy-induced emesis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1

    Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Domperidone; Dronabinol; Drug Therapy,

1986
Domperidone.
    General pharmacology, 1988, Volume: 19, Issue:4

    Topics: Colonic Diseases, Functional; Domperidone; Dyspepsia; Esophagitis, Peptic; Gastrointestinal Motility

1988
Domperidone, a new dopamine antagonist.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1986, Sep-01, Volume: 135, Issue:5

    Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; Dys

1986
[The control of chemotherapy-induced nausea and vomiting].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:7

    Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Chlorpromazine; Cisplatin; Domperidone; Hum

1985

Trials

38 trials available for domperidone and Vomiting

ArticleYear
Antiemetics improve the tolerance of polyethylene glycol for colonoscopy preparation: A randomized clinical trial.
    Medicine, 2021, Mar-12, Volume: 100, Issue:10

    Topics: Adult; Aged; Antiemetics; Cathartics; Colon; Colonoscopy; Domperidone; Female; Humans; Incidence; In

2021
Safety and Efficacy of Low-dose Domperidone for Treating Nausea and Vomiting Due to Acute Gastroenteritis in Children.
    Journal of pediatric gastroenterology and nutrition, 2019, Volume: 69, Issue:4

    Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Domperidone; Double-Blind

2019
One-day versus two-day cleansing for colon capsule endoscopy: a prospective randomized pilot study.
    Gastroenterologia y hepatologia, 2014, Volume: 37, Issue:3

    Topics: Abdominal Pain; Adult; Aged; Bisacodyl; Capsule Endoscopy; Cathartics; Colon; Dietary Fiber; Domperi

2014
Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Domperidone; Double-Blind

2016
Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Antidepressive Agents, Second-Generation; Antiemetics; Area

2010
Domperidone versus cisapride in the treatment of infant regurgitation and increased acid gastro-oesophageal reflux: a pilot study.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:4

    Topics: Antiemetics; Cardiovascular System; Cisapride; Domperidone; Electrocardiography; Esophageal pH Monit

2009
Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial.
    BMC pediatrics, 2011, Feb-10, Volume: 11

    Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Clinical Protocols; Dompe

2011
Domperidone with ORT in the treatment of pediatric acute gastroenteritis in Japan: a multicenter, randomized controlled trial.
    Asia-Pacific journal of public health, 2015, Volume: 27, Issue:2

    Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Domperidone; Drug Therapy

2015
Advances in anti-emetic therapy.
    Cancer treatment reviews, 1984, Volume: 11, Issue:3

    Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Clinical Trials as Topic; Dexamethasone; Do

1984
[Domperidone and metoclopramide in the prevention of postoperative nausea and vomiting].
    Ugeskrift for laeger, 1983, Jun-06, Volume: 145, Issue:23

    Topics: Abortion, Induced; Adolescent; Adult; Clinical Trials as Topic; Domperidone; Double-Blind Method; Fe

1983
Nausea and vomiting during spinal anaesthesia. Effect of metoclopramide and domperidone: a double-blind trial.
    Anaesthesia, 1984, Volume: 39, Issue:2

    Topics: Aged; Anesthesia, Spinal; Blood Pressure; Clinical Trials as Topic; Domperidone; Double-Blind Method

1984
[Clinical evaluation of antiemetics for vomiting due to cancer chemotherapy in children].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:6

    Topics: Adolescent; Antiemetics; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; D

1982
Postoperative vomiting treated with domperidone. A double-blind comparison with metoclopramide and a placebo.
    Acta anaesthesiologica Belgica, 1980, Volume: 31, Issue:2

    Topics: Adult; Aged; Antiemetics; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double-Blind Method

1980
The efficacy of Domperidone (R 33812) in the treatment of postoperative vomiting. A double-blind study with a placebo.
    Der Anaesthesist, 1980, Volume: 29, Issue:9

    Topics: Adolescent; Adult; Aged; Antiemetics; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double-

1980
Double-blind evaluation of domperidone in acute vomiting and dyspeptic disorders.
    The Journal of international medical research, 1981, Volume: 9, Issue:2

    Topics: Aged; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double-Blind Method; Dyspepsia; Female;

1981
[Domperidone as an anti-emetic in antineoplastic chemotherapy].
    Minerva chirurgica, 1981, Jun-15, Volume: 36, Issue:11

    Topics: Aged; Antineoplastic Agents; Benzimidazoles; Clinical Trials as Topic; Domperidone; Female; Gastroin

1981
[The effect of domperidone in the prevention of nausea and vomiting during post-operative recovery period from anesthesia--a double blind study (author's transl)].
    Masui. The Japanese journal of anesthesiology, 1981, Volume: 30, Issue:12

    Topics: Adult; Anesthesia; Clinical Trials as Topic; Domperidone; Double-Blind Method; Female; Humans; Male;

1981
[Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)].
    Der Anaesthesist, 1982, Volume: 31, Issue:4

    Topics: Adult; Aged; Anesthesia; Domperidone; Ether; Ethyl Ethers; Female; Humans; Male; Middle Aged; Postop

1982
Bromocriptine and domperidone in the treatment of Parkinson disease.
    Neurology, 1981, Volume: 31, Issue:6

    Topics: Benzimidazoles; Bromocriptine; Domperidone; Female; Humans; Levodopa; Male; Middle Aged; Nausea; Par

1981
Prophylaxis of delayed nausea and vomiting after cancer chemotherapy.
    The Netherlands journal of medicine, 1995, Volume: 47, Issue:1

    Topics: Adult; Aged; Chi-Square Distribution; Cisplatin; Domperidone; Double-Blind Method; Female; Humans; M

1995
A randomised double blind crossover study of domperidone and prochlorperazine suppositories for controlling emesis in outpatients receiving chemotherapy.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Diarrhea; Domperidone; Double-Blind Method; Female; Humans; Male

1994
[Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:13

    Topics: Adult; Aged; Anorexia; Cisplatin; Domperidone; Drug Therapy, Combination; Female; Granisetron; Human

1993
Neurobehavioral syndrome induced by H2-receptor blocker withdrawal: possible role of prolactin.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:1

    Topics: Adult; Anorexia; Antiemetics; Cimetidine; Domperidone; Female; Histamine H2 Antagonists; Humans; Mal

1997
[Apomorphine for treatment of "off-periods" in Parkinson's disease].
    Harefuah, 1999, Nov-15, Volume: 137, Issue:10

    Topics: Aged; Antiparkinson Agents; Apomorphine; Domperidone; Female; Humans; Injections, Subcutaneous; Levo

1999
Domperidone (R 33 812) as an antiemetic in the treatment of postoperative vomiting. A double blind comparison between two different dosages (4 mg and 10 mg).
    Acta anaesthesiologica Belgica, 1979, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Antiemetics; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double-

1979
Evaluation of the antiemetic effect of domperidon in patients treated with cytostatic drugs.
    Therapia Hungarica (English edition), 1992, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Female; Humans

1992
A comparison of controlled release metoclopramide and domperidone in the treatment of nausea and vomiting.
    The British journal of clinical practice, 1991,Winter, Volume: 45, Issue:4

    Topics: Delayed-Action Preparations; Domperidone; Double-Blind Method; Female; Humans; Male; Metoclopramide;

1991
Comparison of starting antiemetic treatment 24 hours before or concurrently with cytotoxic chemotherapy.
    BMJ (Clinical research ed.), 1989, Feb-18, Volume: 298, Issue:6671

    Topics: Administration, Oral; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials a

1989
Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery.
    British journal of anaesthesia, 1986, Volume: 58, Issue:8

    Topics: Abdomen; Adult; Antiemetics; Clinical Trials as Topic; Domperidone; Droperidol; Female; Humans; Hyst

1986
Nabilone: an alternative antiemetic for cancer chemotherapy.
    Archives of disease in childhood, 1986, Volume: 61, Issue:5

    Topics: Adolescent; Antiemetics; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; D

1986
Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis.
    Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:3

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Domperidone; Double-Blind Method; Dronabinol; Drug

1986
Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:6

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as To

1987
Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following gynaecological surgery in day cases.
    British journal of anaesthesia, 1986, Volume: 58, Issue:8

    Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Antiemetics; Clinical Trials as Topic; Dila

1986
Buprenorphine versus domperidone in chemotherapy-induced emesis: a pilot study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1986, Volume: 6, Issue:2

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Buprenorphine; Clinical Trials as Topic; Domperidon

1986
Domperidone, a new dopamine antagonist.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1986, Sep-01, Volume: 135, Issue:5

    Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; Dys

1986
Domperidone antagonizes bromoergocriptine--induced nausea and vomiting without affecting its inhibition of prolactin secretion in puerperal women.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:5

    Topics: Adult; Bromocriptine; Domperidone; Drug Therapy, Combination; Female; Humans; Hyperprolactinemia; Na

1987
The evaluation of domperidone and metoclopramide as antiemetics in day care abortion patients.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:3

    Topics: Abortion, Therapeutic; Adolescent; Adult; Anesthesia, General; Anesthesia, Obstetrical; Clinical Tri

1985
High-dose alizapride versus high-dose domperidone: a double-blind comparative study in the management of cis-platinum-induced emesis.
    Current medical research and opinion, 1985, Volume: 9, Issue:6

    Topics: Antiemetics; Cisplatin; Clinical Trials as Topic; Domperidone; Double-Blind Method; Female; Humans;

1985

Other Studies

82 other studies available for domperidone and Vomiting

ArticleYear
Impact of Safety Warning on Domperidone Prescribing for Geriatric Patients in South Korea: Analysis of National Insurance Claim Data.
    International journal of environmental research and public health, 2019, 08-20, Volume: 16, Issue:16

    Topics: Aged; Antiemetics; Domperidone; Electrocardiography; Female; Heart Diseases; Humans; Male; Nausea; P

2019
Prophylactic use of antiemetics for prevention of opioid-induced nausea and vomiting: a survey about Italian physicians' practice.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019, Volume: 27, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Analgesics, Opioid; Antiemetics; Antipsychotic Agents; Cross-Section

2019
It Is Ok to Be Negative!
    Journal of pediatric gastroenterology and nutrition, 2019, Volume: 69, Issue:4

    Topics: Child; Domperidone; Gastroenteritis; Humans; Nausea; Vomiting

2019
Awareness of, and Compliance with, Domperidone Revised Labeling After a Risk-Minimization Activity in Europe.
    Clinical drug investigation, 2019, Volume: 39, Issue:11

    Topics: Adult; Antiemetics; Arrhythmias, Cardiac; Cardiac Conduction System Disease; Cross-Sectional Studies

2019
Moderate to severe nausea in radioactive iodine (RAI) therapy is associated with the RAI dose per body weight and was not prevented by ramosetron.
    Endocrine, 2014, Volume: 46, Issue:1

    Topics: Adenoma; Adult; Aged; Antiemetics; Benzimidazoles; Domperidone; Dose-Response Relationship, Radiatio

2014
Domperidone-induced dystonia: a rare and troublesome complication.
    BMJ case reports, 2014, Jun-27, Volume: 2014

    Topics: Adolescent; Antiemetics; Domperidone; Dystonia; Humans; Male; Vomiting

2014
Does Braun enteroenterostomy reduce delayed gastric emptying after pancreaticoduodenectomy?
    Medicine, 2014, Volume: 93, Issue:7

    Topics: Abdominal Abscess; Acupuncture; Anastomotic Leak; Antiemetics; Domperidone; Enterostomy; Erythromyci

2014
Drug treatment of adults with nausea and vomiting in primary care.
    BMJ (Clinical research ed.), 2014, Aug-07, Volume: 349

    Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopra

2014
Cardiovascular safety profile and clinical experience with high-dose domperidone therapy for nausea and vomiting.
    The American journal of the medical sciences, 2015, Volume: 349, Issue:5

    Topics: Adult; Cardiotoxicity; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Mon

2015
Prophylactic Use of Antiemetics for Prevention of Opioid-Induced Nausea and Vomiting: A Questionnaire Survey among Japanese Physicians.
    Journal of palliative medicine, 2015, Volume: 18, Issue:11

    Topics: Analgesics, Opioid; Antiemetics; Benzodiazepines; Chemoprevention; Domperidone; Health Care Surveys;

2015
Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:12

    Topics: Adult; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Diarrhea; Domperidone; Dopamine An

2016
Domperidone and sudden death. Cardiac rhythm disorders: QT interval prolongation.
    Prescrire international, 2008, Volume: 17, Issue:94

    Topics: Antiemetics; Arrhythmias, Cardiac; Canada; Death, Sudden, Cardiac; Domperidone; Humans; Long QT Synd

2008
[Efficacy of preventive treatment for delayed emesis induced by FOLFOX4 chemotherapy].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2009, Volume: 129, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dexamethasone; Do

2009
Tolerance to enteral nutrition therapy in traumatic brain injury patients.
    Brain injury, 2012, Volume: 26, Issue:9

    Topics: Adult; Aged; Antiemetics; Brain Injuries; Cross-Sectional Studies; Domperidone; Enteral Nutrition; E

2012
Case series: paradoxical action of domperidone leads to increased vomiting.
    European journal of clinical pharmacology, 2013, Volume: 69, Issue:2

    Topics: Child; Child, Preschool; Domperidone; Enteral Nutrition; Female; Humans; Infant; Male; Vomiting

2013
Case report--the 46 year old man with a 5 month history of vomiting.
    Malawi medical journal : the journal of Medical Association of Malawi, 2011, Volume: 23, Issue:2

    Topics: Antiemetics; Diabetes Mellitus, Type 2; Diagnosis, Differential; Domperidone; Gastroparesis; Humans;

2011
Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2002, Volume: 63, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma; Domperidone; Dose Fractionation, Radiatio

2002
Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew).
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: Animals; Antiemetics; Butanols; Capsaicin; Cyclooxygenase Inhibitors; Dihydroergotamine; Diphenhydra

2005
Differential action of domperidone to modify emesis and behaviour induced by apomorphine in the ferret.
    European journal of pharmacology, 2005, Jun-15, Volume: 516, Issue:3

    Topics: Animals; Antiemetics; Antiparkinson Agents; Apomorphine; Behavior, Animal; Domperidone; Ferrets; Hab

2005
Antiemetics for children with gastroenteritis: off-label but still on in clinical practice.
    Journal of pediatric gastroenterology and nutrition, 2006, Volume: 43, Issue:3

    Topics: Acute Disease; Administration, Rectal; Antiemetics; Child, Preschool; Domperidone; Gastroenteritis;

2006
Dosage and drug interactions of domperidone.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:4

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Drug Interactions; Drug Labeling; Gastrointestinal D

2008
Extrapyramidal reactions due to domperidone.
    Lancet (London, England), 1980, Oct-11, Volume: 2, Issue:8198

    Topics: Adult; Antiemetics; Basal Ganglia Diseases; Benzimidazoles; Domperidone; Female; Humans; Infant; Mal

1980
Sudden death in cancer patient on high-dose domperidone.
    Lancet (London, England), 1982, May-01, Volume: 1, Issue:8279

    Topics: Aged; Carcinoma, Squamous Cell; Death, Sudden; Domperidone; Esophageal Neoplasms; Humans; Male; Vomi

1982
Gynecomastia in a male infant given domperidone.
    Lancet (London, England), 1982, Oct-16, Volume: 2, Issue:8303

    Topics: Domperidone; Female; Galactorrhea; Gynecomastia; Humans; Infant; Male; Pregnancy; Vomiting

1982
Refusal of further cancer chemotherapy due to antiemetic drug.
    Lancet (London, England), 1984, Jan-07, Volume: 1, Issue:8367

    Topics: Antineoplastic Agents; Child; Domperidone; Drug Therapy, Combination; Dystonia; Female; Humans; Pati

1984
Two sudden deaths during prophylactic antiemetic treatment with high doses of domperidone and methylprednisolone.
    Lancet (London, England), 1984, Dec-08, Volume: 2, Issue:8415

    Topics: Cisplatin; Death, Sudden; Domperidone; Drug Therapy, Combination; Humans; Methylprednisolone; Middle

1984
[Metadoxine in the treatment of vomiting in uremic patients under dialysis treatment].
    La Clinica terapeutica, 1984, Aug-15, Volume: 110, Issue:3

    Topics: Adolescent; Adult; Aged; Domperidone; Drug Combinations; Humans; Middle Aged; Pyridoxine; Pyrrolidin

1984
[Pharmacotherapy of emesis caused by cytostatic agents].
    Nederlands tijdschrift voor geneeskunde, 1982, May-01, Volume: 126, Issue:18

    Topics: Antiemetics; Antineoplastic Agents; Domperidone; Dronabinol; Humans; Metoclopramide; Phenothiazines;

1982
Increased vomiting induced by an antiemetic drug.
    Archives of disease in childhood, 1984, Volume: 59, Issue:3

    Topics: Alginates; Aluminum Hydroxide; Antacids; Bezoars; Bicarbonates; Domperidone; Drug Combinations; Huma

1984
Altered gastric emptying and prevention of radiation-induced vomiting in dogs.
    Gastroenterology, 1984, Volume: 86, Issue:3

    Topics: Animals; Cobalt Radioisotopes; Dogs; Domperidone; Gastric Emptying; Male; Radiation Injuries, Experi

1984
Seizures after antiemetic treatment with high dose domperidone: report of four cases.
    British medical journal (Clinical research ed.), 1984, Jun-09, Volume: 288, Issue:6432

    Topics: Adult; Blood Glucose; Calcium; Cisplatin; Domperidone; Epilepsy, Tonic-Clonic; Humans; Magnesium; Po

1984
Cardiac arrest after treatment with intravenous domperidone.
    British medical journal (Clinical research ed.), 1984, Dec-08, Volume: 289, Issue:6458

    Topics: Adult; Domperidone; Female; Heart Arrest; Humans; Middle Aged; Nausea; Vomiting

1984
[Domperidone suppositories treatment for nausea and vomiting during cancer chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Domperidone; Female; Humans; Male; Middle Aged; Naus

1984
[Effects of domperidone suppository against adverse reactions in digestive organs induced by cancer chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 2

    Topics: Adult; Aged; Anorexia; Antineoplastic Agents; Domperidone; Female; Hodgkin Disease; Humans; Leukemia

1984
[Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents; Chlorpromazine; Domperidone; Female; Humans; Male; Middle Aged;

1983
Alleviation of chemotherapy induced emesis by oral lorazepam and domperidone.
    Irish journal of medical science, 1983, Volume: 152, Issue:9

    Topics: Adult; Antineoplastic Agents; Domperidone; Drug Therapy, Combination; Female; Humans; Lorazepam; Mal

1983
[Domperidone (Motilium)].
    Harefuah, 1982, Apr-15, Volume: 102, Issue:8

    Topics: Adolescent; Adult; Domperidone; Humans; Vomiting

1982
[Pharmacotherapy of emesis resulting from cytostatic agents].
    Nederlands tijdschrift voor geneeskunde, 1982, Aug-28, Volume: 126, Issue:35

    Topics: Adult; Antineoplastic Agents; Domperidone; Dystonia; Female; Humans; Vomiting

1982
[Nausea and vomiting: pharmacologic aspects].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1982, Volume: 44, Issue:3-4

    Topics: Animals; Antiemetics; Dogs; Domperidone; Humans; Nausea; Receptors, Dopamine; Vomiting

1982
[Domperidon--a new gastrokinetic and anti-emetic without central-nervous side effects].
    Medizinische Klinik, 1980, Jun-06, Volume: 75, Issue:12

    Topics: Acetylcholine; Acetylcholinesterase; Antiemetics; Benzimidazoles; Domperidone; Dyspepsia; Enzyme Inh

1980
The effects of orally administered Y-25130, a selective serotonin3-receptor antagonist, on chemotherapeutic agent-induced emesis.
    Japanese journal of pharmacology, 1993, Volume: 63, Issue:3

    Topics: Administration, Oral; Animals; Antiemetics; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, He

1993
[Prokinetic drugs in digestive disorders].
    La Clinica terapeutica, 1993, Volume: 143, Issue:3

    Topics: Antineoplastic Agents; Cisapride; Domperidone; Esophageal Motility Disorders; Gastroesophageal Reflu

1993
Pica in rats is analogous to emesis: an animal model in emesis research.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:4

    Topics: Animals; Antiemetics; Apomorphine; Cisplatin; Copper; Copper Sulfate; Disease Models, Animal; Domper

1993
Gastroprokinetic effect of a new benzamide derivative itopride and its action mechanisms in conscious dogs.
    Japanese journal of pharmacology, 1996, Volume: 71, Issue:2

    Topics: Animals; Antiemetics; Apomorphine; Benzamides; Benzyl Compounds; Dogs; Domperidone; Dopamine Antagon

1996
The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:6

    Topics: Abdominal Pain; Administration, Oral; Adult; Aged; Antiemetics; Domperidone; Dopamine Antagonists; E

1997
[Multi-drug antiemetic treatment and effect of treatment duration of concurrent steroids--for complete control of chemotherapy-induced nausea/vomiting in gynecological cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:15

    Topics: Administration, Oral; Adult; Aged; Anti-Anxiety Agents; Antiemetics; Antineoplastic Combined Chemoth

1997
Radiation-induced emesis: a prospective observational multicenter Italian trial. The Italian Group for Antiemetic Research in Radiotherapy.
    International journal of radiation oncology, biology, physics, 1999, Jun-01, Volume: 44, Issue:3

    Topics: Adult; Antiemetics; Domperidone; Drug Administration Schedule; Female; Humans; Incidence; Indoles; M

1999
Gastric relaxation by morphine, apomorphine and fentanyl in the conscious dog.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 242, Issue:2

    Topics: Animals; Apomorphine; Benzimidazoles; Dogs; Domperidone; Fentanyl; Haloperidol; Morphine; Muscle Con

1979
The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors.
    Neuropharmacology, 1992, Volume: 31, Issue:8

    Topics: Animals; Behavior, Animal; Cerebral Ventricles; Domperidone; Female; Fenclonine; Ferrets; Loperamide

1992
Some possible gynaecological indications for peripheral antidopamine therapy.
    Therapia Hungarica (English edition), 1992, Volume: 40, Issue:1

    Topics: Adult; Climacteric; Domperidone; Drug Evaluation; Dyspepsia; Female; Gastrointestinal Diseases; Huma

1992
The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting.
    Therapia Hungarica (English edition), 1990, Volume: 38, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Dimenhydrinate; Domperidone; Femal

1990
Functional localization of specific receptors mediating gastrointestinal motor correlates of vomiting.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: Animals; Apomorphine; Atropine; Copper; Copper Sulfate; Digestive System; Dogs; Domperidone; Female;

1989
Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats.
    American journal of veterinary research, 1989, Volume: 50, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Cat Diseases; Cats; Ch

1989
Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting.
    Therapia Hungarica (English edition), 1989, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Aged; Domperidone; Dyspepsia; Female; Genital Diseases, Female; Humans; Hyperemes

1989
Cardiotoxicity of intravenous domperidone.
    Lancet (London, England), 1985, Aug-17, Volume: 2, Issue:8451

    Topics: Arrhythmias, Cardiac; Domperidone; Female; Humans; Infusions, Parenteral; Vomiting

1985
Effects of dopamine receptor antagonists on gastrin and vomiting responses to apomorphine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Dogs; Domperidone; Female; Gastrins; Male;

1987
Continuous ECG monitoring of children with cancer receiving domperidone.
    Pediatric hematology and oncology, 1986, Volume: 3, Issue:4

    Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Child

1986
Effect of ionizing radiation on gastric secretion and gastric motility in monkeys.
    Gastroenterology, 1985, Volume: 89, Issue:2

    Topics: Animals; beta-Endorphin; Domperidone; Electrophysiology; Endorphins; Fasting; Gastric Emptying; Gast

1985
Mechanisms of radiation-induced emesis in the dog.
    Pharmacology & therapeutics, 1988, Volume: 39, Issue:1-3

    Topics: Animals; Dogs; Domperidone; Electrophysiology; Female; Indomethacin; Male; Radiation Injuries, Exper

1988
Use of Motilium in the perioperative period from the aspect of the anaesthesiologist.
    Therapia Hungarica (English edition), 1988, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Domperidone; Female; Humans; Middle Aged; Nausea; Preanesthetic Medication; Vomit

1988
Domperidone: an alternative to metoclopramide.
    Drug and therapeutics bulletin, 1988, Jul-25, Volume: 26, Issue:15

    Topics: Acute Disease; Adolescent; Adult; Child; Domperidone; Humans; Metoclopramide; Nausea; Vomiting

1988
Domperidone.
    The Australian nurses' journal. Royal Australian Nursing Federation, 1988, Volume: 18, Issue:3

    Topics: Domperidone; Humans; Nausea; Vomiting

1988
Effect of domperidone on postoperative vomiting and dyspepsia aggravated by operation.
    Therapia Hungarica (English edition), 1988, Volume: 36, Issue:3

    Topics: Adult; Domperidone; Dyspepsia; Female; Humans; Middle Aged; Nausea; Postoperative Complications; Pre

1988
Use of Motilium with gastrokinetic and anti-emetic action in outpatients.
    Therapia Hungarica (English edition), 1988, Volume: 36, Issue:3

    Topics: Adult; Ambulatory Care; Domperidone; Female; Gastrointestinal Motility; Humans; Hungary; Male; Middl

1988
[Emetic and catalepsy-inducing actions of buflomedil].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1988, Volume: 92, Issue:6

    Topics: Administration, Oral; Animals; Bromocriptine; Catalepsy; Dogs; Domperidone; Dose-Response Relationsh

1988
Dopamine antagonist domperidone (Motilium) in everyday clinical practice.
    Therapia Hungarica (English edition), 1988, Volume: 36, Issue:4

    Topics: Adult; Aged; Domperidone; Dyspepsia; Female; Humans; Male; Middle Aged; Nausea; Vomiting

1988
Evidence that 5-hydroxytryptamine3 receptors mediate cytotoxic drug and radiation-evoked emesis.
    British journal of cancer, 1987, Volume: 56, Issue:2

    Topics: Animals; Antineoplastic Agents; Apomorphine; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Ci

1987
[Use of estrogens in post-coital contraception. Our case material of 243 cases].
    Minerva ginecologica, 1988, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Contraceptives, Postcoital; Contraceptives, Postcoital, Hormonal; Domperidone; Es

1988
Characterization of radiation-induced emesis in the ferret.
    Radiation research, 1988, Volume: 114, Issue:3

    Topics: Animals; Apomorphine; Carnivora; Cobalt Radioisotopes; Domperidone; Emetics; Ferrets; Gamma Rays; Ma

1988
Observations with dopamine antagonist domperidone (Motilium) in controlling postoperative dyspepsias and vomiting.
    Therapia Hungarica (English edition), 1987, Volume: 35, Issue:2

    Topics: Abdomen; Adult; Aged; Domperidone; Dyspepsia; Female; Humans; Male; Middle Aged; Postoperative Compl

1987
Evaluation of domperidone as a modifier of gamma-radiation-induced emesis.
    International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:9

    Topics: Animals; Antiemetics; Cimetidine; Cobalt Radioisotopes; Dexamethasone; Dogs; Domperidone; Drug Thera

1987
[Acute dystonic reaction due to domperidone in a infant].
    Harefuah, 1986, Mar-02, Volume: 110, Issue:5

    Topics: Domperidone; Dystonia; Humans; Infant; Male; Vomiting

1986
[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Drug Evaluation; Female; H

1986
Radiation-induced emesis in the dog: effects of lesions and drugs.
    Radiation research, 1986, Volume: 108, Issue:3

    Topics: Animals; Apomorphine; Cerebral Ventricles; Dogs; Domperidone; Indomethacin; Neurons; Prostaglandins;

1986
Extrapyramidal dysfunction after domperidone.
    Helvetica paediatrica acta, 1985, Volume: 40, Issue:1

    Topics: Basal Ganglia Diseases; Domperidone; Humans; Infant; Male; Vomiting

1985
Domperidone.
    British medical journal (Clinical research ed.), 1985, Mar-09, Volume: 290, Issue:6470

    Topics: Domperidone; Humans; Parkinson Disease; Vomiting

1985
Studies on mechanism of retching and vomiting in dogs. Effect of peripheral dopamine blocker on myoelectric changes in antrum and upper small intestine.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:1

    Topics: Animals; Copper; Copper Sulfate; Dogs; Domperidone; Dopamine; Duodenum; Electrophysiology; Jejunum;

1985
Influence of peripheral and central administration of apomorphine and morphine on intragastric pressure in the dog.
    European journal of pharmacology, 1985, Jan-02, Volume: 107, Issue:2

    Topics: Animals; Apomorphine; Brain; Chemoreceptor Cells; Dogs; Domperidone; Female; Injections, Intravenous

1985
[Effect of combined use of adrenocortical hormones and domperidone as anti-emetics during cisplatin therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Cisplatin; Domperidone; Drug Therapy, Combination; Esophageal Neoplas

1985
A pilot study of high-dose domperidone as an antiemetic in patients treated with cisplatin.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:7

    Topics: Adolescent; Adult; Aged; Cisplatin; Domperidone; Female; Humans; Infusions, Parenteral; Male; Middle

1985
Review of the current status of prokinetic agents in gastroenterology.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:12

    Topics: Benzamides; Chemical Phenomena; Chemistry; Cisapride; Dexamethasone; Digestive System; Domperidone;

1985
Sequential therapy with lithium in chemotherapy-induced vomiting.
    Tumori, 1985, Dec-31, Volume: 71, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Drug Evaluatio

1985