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domperidone and Tachycardia

domperidone has been researched along with Tachycardia in 4 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

Research Excerpts

ExcerptRelevanceReference
"There is increased awareness about risks and benefits of using domperidone to treat gastroparesis."7.83Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016)
"A central dopaminergic origin has been demonstrated for the bromocriptine-induced tachycardia in conscious, normotensive rats."7.71Central bromocriptine-induced tachycardia is reversed to bradycardia in conscious, deoxycorticosterone acetate-salt hypertensive rats. ( Lahlou, S, 2001)
"These results suggest that in anaesthetised and conscious normotensive rats, the bromocriptine induced tachycardia is not related to a release of adrenaline from the adrenal medulla but could be elicited by central dopamine D-2 receptor stimulation through a possible increase in cardiac sympathetic tone."7.68Central dopaminergic origin of bromocriptine induced tachycardia in normotensive rats. ( Demenge, P; Duarte, GP; Lahlou, S, 1993)
" Because dopaminergic receptor agonists reduce sympathetic outflow, this study assessed effectiveness of the available dopaminergic agonist, bromocriptine, in slowing or terminating ouabain-induced ventricular tachycardia in anesthetized dogs."7.67Bromocriptine treatment of digitalis-induced ventricular tachyarrhythmias: studies in a canine model. ( Benditt, DG; Benson, DW; Detloff, BL; Kao, A; Kriett, JM; Pritzker, MR; Tobler, HG, 1984)
"There is increased awareness about risks and benefits of using domperidone to treat gastroparesis."3.83Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016)
"A central dopaminergic origin has been demonstrated for the bromocriptine-induced tachycardia in conscious, normotensive rats."3.71Central bromocriptine-induced tachycardia is reversed to bradycardia in conscious, deoxycorticosterone acetate-salt hypertensive rats. ( Lahlou, S, 2001)
"These results suggest that in anaesthetised and conscious normotensive rats, the bromocriptine induced tachycardia is not related to a release of adrenaline from the adrenal medulla but could be elicited by central dopamine D-2 receptor stimulation through a possible increase in cardiac sympathetic tone."3.68Central dopaminergic origin of bromocriptine induced tachycardia in normotensive rats. ( Demenge, P; Duarte, GP; Lahlou, S, 1993)
" Because dopaminergic receptor agonists reduce sympathetic outflow, this study assessed effectiveness of the available dopaminergic agonist, bromocriptine, in slowing or terminating ouabain-induced ventricular tachycardia in anesthetized dogs."3.67Bromocriptine treatment of digitalis-induced ventricular tachyarrhythmias: studies in a canine model. ( Benditt, DG; Benson, DW; Detloff, BL; Kao, A; Kriett, JM; Pritzker, MR; Tobler, HG, 1984)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schey, R1
Saadi, M1
Midani, D1
Roberts, AC1
Parupalli, R1
Parkman, HP1
Kao, A1
Kriett, JM1
Tobler, HG1
Detloff, BL1
Pritzker, MR1
Benson, DW1
Benditt, DG1
Lahlou, S2
Duarte, GP1
Demenge, P1

Other Studies

4 other studies available for domperidone and Tachycardia

ArticleYear
Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:12

    Topics: Adult; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Diarrhea; Domperidone; Dopamine An

2016
Bromocriptine treatment of digitalis-induced ventricular tachyarrhythmias: studies in a canine model.
    Journal of the American College of Cardiology, 1984, Volume: 4, Issue:6

    Topics: Animals; Blood Pressure; Bromocriptine; Dogs; Domperidone; Female; Haloperidol; Male; Ouabain; Preme

1984
Central dopaminergic origin of bromocriptine induced tachycardia in normotensive rats.
    Cardiovascular research, 1993, Volume: 27, Issue:11

    Topics: Adrenalectomy; Animals; Blood Pressure; Bromocriptine; Domperidone; Dopamine D2 Receptor Antagonists

1993
Central bromocriptine-induced tachycardia is reversed to bradycardia in conscious, deoxycorticosterone acetate-salt hypertensive rats.
    Pharmacology & toxicology, 2001, Volume: 88, Issue:5

    Topics: Animals; Aorta, Abdominal; Blood Pressure; Bradycardia; Bromocriptine; Desoxycorticosterone; Domperi

2001