Page last updated: 2024-10-26

domperidone and Syncope

domperidone has been researched along with Syncope in 2 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)

Research Excerpts

ExcerptRelevanceReference
"To study the efficacy of medical treatment for preventing syncopal recurrences in patients affected by tilt-induced neurally mediated syncope, a randomized placebo-treatment prospective study was performed in 30 patients (10 men and 20 women, mean age 42 +/- 21 years) who had syncope reproduced in 2 consecutive head-up tilt-table tests without pharmacologic intervention (n = 20) or during isoproterenol infusion (n = 10)."5.07A controlled trial of acute and long-term medical therapy in tilt-induced neurally mediated syncope. ( Bottoni, N; Brignole, M; Gianfranchi, L; Lolli, G; Menozzi, C; Oddone, D, 1992)
"Migraine suffers who experience spontaneous syncopes (syncopal migraine) during attacks exhibit a dramatic intolerance to bromocriptine, a dopamine agonist."3.66A new nonvascular interpretation of syncopal migraine. ( Boccuni, M; Bonciani, M; D'Egidio, P; Fanciullacci, M; Sicuteri, F, 1982)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sicuteri, F1
Boccuni, M1
Fanciullacci, M1
D'Egidio, P1
Bonciani, M1
Brignole, M1
Menozzi, C1
Gianfranchi, L1
Lolli, G1
Bottoni, N1
Oddone, D1

Trials

1 trial available for domperidone and Syncope

ArticleYear
A controlled trial of acute and long-term medical therapy in tilt-induced neurally mediated syncope.
    The American journal of cardiology, 1992, Aug-01, Volume: 70, Issue:3

    Topics: Adult; Atenolol; Bandages; Dihydroergotamine; Domperidone; Female; Humans; Isoproterenol; Male; Midd

1992

Other Studies

1 other study available for domperidone and Syncope

ArticleYear
A new nonvascular interpretation of syncopal migraine.
    Advances in neurology, 1982, Volume: 33

    Topics: Adolescent; Adult; Blood Pressure; Bromocriptine; Domperidone; Female; Humans; Hypotension; Male; Mi

1982