Page last updated: 2024-10-26

domperidone and Swine Diseases

domperidone has been researched along with Swine Diseases in 2 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Swine Diseases: Diseases of domestic swine and of the wild boar of the genus Sus.

Research Excerpts

ExcerptRelevanceReference
"Objectives of this experiment were to determine if the domperidone protocol previously used for gestating gilts can also lead to hyperprolactinemia in growing gilts, and to assess the effects of such a protocol on hormonal status, mammary development and gene expression in mammary and pituitary tissue of gilts at puberty."8.02Hyperprolactinemia using domperidone in prepubertal gilts: Effects on hormonal status, mammary development and mammary and pituitary gene expression. ( Farmer, C; Palin, MF, 2021)
"Objectives of this experiment were to determine if the domperidone protocol previously used for gestating gilts can also lead to hyperprolactinemia in growing gilts, and to assess the effects of such a protocol on hormonal status, mammary development and gene expression in mammary and pituitary tissue of gilts at puberty."4.02Hyperprolactinemia using domperidone in prepubertal gilts: Effects on hormonal status, mammary development and mammary and pituitary gene expression. ( Farmer, C; Palin, MF, 2021)
" We hypothesized that inducing hyperprolactinemia in primiparous gilts during late gestation by administering the dopamine antagonist domperidone (DOM) would increase MG epithelial cell proliferation and differentiation, subsequent milk yield, and piglet growth."3.79Late gestational hyperprolactinemia accelerates mammary epithelial cell differentiation that leads to increased milk yield. ( Hovey, RC; Manjarin, R; McMicking, HF; Trott, JF; Vanklompenberg, MK, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Farmer, C1
Palin, MF1
Vanklompenberg, MK1
Manjarin, R1
Trott, JF1
McMicking, HF1
Hovey, RC1

Other Studies

2 other studies available for domperidone and Swine Diseases

ArticleYear
Hyperprolactinemia using domperidone in prepubertal gilts: Effects on hormonal status, mammary development and mammary and pituitary gene expression.
    Domestic animal endocrinology, 2021, Volume: 76

    Topics: Animals; Domperidone; Female; Gene Expression; Hyperprolactinemia; Lactation; Mammary Glands, Animal

2021
Late gestational hyperprolactinemia accelerates mammary epithelial cell differentiation that leads to increased milk yield.
    Journal of animal science, 2013, Volume: 91, Issue:3

    Topics: Animals; Cell Differentiation; Cell Proliferation; Domperidone; Dopamine Antagonists; Epithelial Cel

2013