domperidone has been researched along with Stomach Ulcer in 15 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of domperidone, a peripheral dopamine receptor antagonist, has been studied in the aspirin, phenylbutazone and reserpine induced gastric ulcers in rats." | 7.67 | Effect of domperidone on experimentally induced gastric ulcers in rats. ( Ageel, AM; Al-Khamis, KI; Parmar, NS; Tariq, M, 1986) |
| " The aim of this study was to examine the effects of dopamine receptor agonists and antagonists on gastric acid secretion and gastroduodenal ulcer formation induced by cysteamine injection in rats." | 3.67 | [Effects of dopamine receptor agonists and antagonists on an experimental ulcer system induced by cysteamine in rats--dopaminergic mechanism vs pathogenesis of peptic ulceration]. ( Kondoh, Y, 1988) |
| "The effect of domperidone, a peripheral dopamine receptor antagonist, has been studied in the aspirin, phenylbutazone and reserpine induced gastric ulcers in rats." | 3.67 | Effect of domperidone on experimentally induced gastric ulcers in rats. ( Ageel, AM; Al-Khamis, KI; Parmar, NS; Tariq, M, 1986) |
| "A single dose of the dopamine agonists L-dopa, bromocriptine or apomorphine produced a protective effect by significantly shortening of the length of stomach ulcerations." | 3.67 | The role of dopamine in the formation of gastric ulcers in rats. ( Aleksić, J; Geber, J; Gjuris, V; Ivanović, D; Marović, A; Reić, P; Sikirić, P; Suchanek, E, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (80.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lux, G | 1 |
| Rösch, W | 1 |
| Hernandez, DE | 1 |
| Adcock, JW | 1 |
| Orlando, RC | 1 |
| Patrick, KS | 1 |
| Nemeroff, CB | 1 |
| Prange, AJ | 1 |
| Schneider, JA | 1 |
| Bauer, H | 1 |
| Doenicke, A | 1 |
| Heinkelein, J | 1 |
| Grabarević, Z | 1 |
| Rotkvić, I | 2 |
| Sikirić, P | 3 |
| Seiwerth, S | 1 |
| Dzaja, P | 1 |
| Perić, J | 1 |
| Kos, J | 1 |
| Guidobono, F | 1 |
| Pagani, F | 1 |
| Sibilia, V | 1 |
| Soglian, A | 1 |
| Rapetti, D | 1 |
| Netti, C | 1 |
| Jian, R | 1 |
| Kondoh, Y | 1 |
| Willis, GL | 1 |
| Sleeman, M | 1 |
| Brodie, G | 1 |
| Smith, GC | 1 |
| Fukumoto, S | 1 |
| Amano, Y | 1 |
| Fukuda, R | 1 |
| Gobaru, Y | 1 |
| Adachi, K | 1 |
| Ashizawa, N | 1 |
| Yoshida, H | 1 |
| Watanabe, M | 1 |
| Shimada, Y | 1 |
| Glavin, GB | 1 |
| Dugani, AM | 1 |
| Geber, J | 2 |
| Ivanović, D | 2 |
| Suchanek, E | 2 |
| Gjuris, V | 2 |
| Tućan-Foretić, M | 1 |
| Mise, S | 1 |
| Cvitanović, B | 1 |
| Parmar, NS | 1 |
| Tariq, M | 1 |
| Ageel, AM | 1 |
| Al-Khamis, KI | 1 |
| Drago, F | 1 |
| Continella, G | 1 |
| Conforto, G | 1 |
| Scapagnini, U | 1 |
| Aleksić, J | 1 |
| Reić, P | 1 |
| Marović, A | 1 |
2 reviews available for domperidone and Stomach Ulcer
| Article | Year |
|---|---|
[Conservative treatment of gastric ulcer].
Topics: Aluminum; Antacids; Anti-Ulcer Agents; Benzimidazoles; Carbenoxolone; Domperidone; Gefarnate; Glycyr | 1980 |
[Disorders of gastric emptying].
Topics: Cisapride; Diabetes Complications; Domperidone; Dyspepsia; Gastric Emptying; Gastroesophageal Reflux | 1992 |
1 trial available for domperidone and Stomach Ulcer
| Article | Year |
|---|---|
[Influence of domperidone and metoclopramide on serum gastrin levels and gastric acid secretion (author's transl)].
Topics: Adult; Antiemetics; Benzimidazoles; Domperidone; Gastric Acid; Gastrins; Gastrointestinal Motility; | 1981 |
12 other studies available for domperidone and Stomach Ulcer
| Article | Year |
|---|---|
Prevention of stress-induced gastric ulcers by dopamine agonists in the rat.
Topics: Animals; Apomorphine; Dextroamphetamine; Domperidone; Dopamine; Male; Methylphenidate; Rats; Rats, I | 1984 |
[Gastritis, stomach ulcer, reflux diseases. Motility effective therapy with Motilium].
Topics: Adult; Domperidone; Duodenal Ulcer; Esophagitis, Peptic; Female; Gastritis; Gastroesophageal Reflux; | 1982 |
Brain-mediated protective interactions of histaminergic H2 and dopaminergic systems in rats.
Topics: Animals; Apomorphine; Bromocriptine; Cimetidine; Domperidone; Dopamine Agonists; Dopamine Antagonist | 1997 |
The role of sensory neurons in the antiulcer effect of centrally injected amylin in rat.
Topics: Adrenergic alpha-Antagonists; Amyloid; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; | 2000 |
[Effects of dopamine receptor agonists and antagonists on an experimental ulcer system induced by cysteamine in rats--dopaminergic mechanism vs pathogenesis of peptic ulceration].
Topics: Animals; Cysteamine; Domperidone; Dopamine; Duodenal Ulcer; Male; Rats; Rats, Inbred Strains; Recept | 1988 |
Observations on dopamine receptor antagonists and gastric ulceration associated with experimental anorexia cachexia.
Topics: Animals; Anorexia; Cachexia; Carcinoma 256, Walker; Domperidone; Dopamine; Dopamine Antagonists; Dri | 1988 |
Gastric emptying in deformed stomach.
Topics: Acetaminophen; Adult; Aged; Domperidone; Female; Gastric Acid; Gastric Emptying; Humans; Male; Middl | 1987 |
Effects of dopamine agonists and antagonists on gastric acid secretion and stress responses in rats.
Topics: Animals; Corticosterone; Domperidone; Dopamine; Dopamine Antagonists; Gastric Juice; Immobilization; | 1987 |
Dopamine antagonists induce gastric lesions in rats.
Topics: Animals; Bromocriptine; Domperidone; Dopamine Antagonists; Female; Haloperidol; Levodopa; Male; Meto | 1986 |
Effect of domperidone on experimentally induced gastric ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Domperidone; Female; Gastric Mucosa; Male; Phenylbutazone; Rats | 1986 |
Prolactin inhibits the development of stress-induced ulcers in the rat.
Topics: Animals; Domperidone; Haloperidol; Indomethacin; Kidney; Male; Pituitary Gland, Anterior; Prolactin; | 1985 |
The role of dopamine in the formation of gastric ulcers in rats.
Topics: Animals; Apomorphine; Bromocriptine; Domperidone; Dopamine; Female; Haloperidol; Levodopa; Male; Rat | 1985 |