Page last updated: 2024-10-26

domperidone and Sleep Apnea, Obstructive

domperidone has been researched along with Sleep Apnea, Obstructive in 3 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

Research Excerpts

ExcerptRelevanceReference
"Pharmacological treatment of obstructive sleep apnea with a combination of pseudoephedrine and domperidone."1.36Pharmacological treatment of obstructive sleep apnea with a combination of pseudoephedrine and domperidone. ( Gooley, TA; Kapur, VK; Larrain, A; Pope, CE, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Larrain, A1
Kapur, VK1
Gooley, TA1
Pope, CE1
Strohl, KP1
Nasr, VG1
Bitar, MA1
Chehade, JM1
Dagher, WI1
Baraka, AS1

Other Studies

3 other studies available for domperidone and Sleep Apnea, Obstructive

ArticleYear
Pharmacological treatment of obstructive sleep apnea with a combination of pseudoephedrine and domperidone.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2010, Apr-15, Volume: 6, Issue:2

    Topics: Adult; Aged; Antiemetics; Bronchodilator Agents; Domperidone; Drug Therapy, Combination; Female; Fol

2010
Drug trials for obstructive sleep apnea.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2010, Apr-15, Volume: 6, Issue:2

    Topics: Animals; Antiemetics; Bronchodilator Agents; Clinical Trials as Topic; Domperidone; Drug Therapy, Co

2010
Postoperative severe uvular edema following tonsillectomy in a child with a history of obstructive sleep apnea.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:7

    Topics: Adenoids; Antiemetics; Catheter Ablation; Domperidone; Edema; Enzyme Inhibitors; Humans; Infant; Mal

2008