domperidone has been researched along with Sialorrhea in 1 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Sialorrhea: Increased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with domperidone (1 or 2 mg/kg body weight) or the ablation of the area postrema (AP) abolished the gastric motor response and salivary secretion induced by the administration of apomorphine." | 1.32 | Area postrema mediates gastric motor response induced by apomorphine in rats. ( Kobashi, M; Koga, T; Matsuo, R; Mizutani, M; Tsukamoto, G, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koga, T | 1 |
| Kobashi, M | 1 |
| Mizutani, M | 1 |
| Tsukamoto, G | 1 |
| Matsuo, R | 1 |
1 other study available for domperidone and Sialorrhea
| Article | Year |
|---|---|
Area postrema mediates gastric motor response induced by apomorphine in rats.
Topics: Animals; Apomorphine; Area Postrema; Autonomic Nervous System; Domperidone; Dopamine Antagonists; Do | 2003 |