domperidone has been researched along with Pregnancy in 81 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone is widely used during pregnancy, although the risks associated with pregnant women have not been adequately evaluated." | 8.02 | Risk of Pregnancy Termination and Congenital Anomalies After Domperidone Exposure: A Study in the EFEMERIS Database. ( Araujo, M; Benevent, J; Damase-Michel, C; Hurault-Delarue, C; Lacroix, I; Sommet, A; Vabre, C, 2021) |
| "Objectives of this experiment were to determine if the domperidone protocol previously used for gestating gilts can also lead to hyperprolactinemia in growing gilts, and to assess the effects of such a protocol on hormonal status, mammary development and gene expression in mammary and pituitary tissue of gilts at puberty." | 8.02 | Hyperprolactinemia using domperidone in prepubertal gilts: Effects on hormonal status, mammary development and mammary and pituitary gene expression. ( Farmer, C; Palin, MF, 2021) |
| " The dopamine receptor antagonist domperidone can increase circulating prolactin concentrations in pigs, but the ideal dose to achieve sustained hyperprolactinemia remains unknown." | 7.91 | Using domperidone to induce and sustain hyperprolactinemia in late-pregnant gilts. ( Farmer, C; Hovey, RC; Mathews, AT, 2019) |
| "The aim of this study is to examine the relationship between domperidone (commonly used off-label for lactation stimulation), ventricular arrhythmia and all-cause mortality during the postpartum period." | 7.83 | The association between domperidone and ventricular arrhythmia in the postpartum period. ( Hanley, GE; Mintzes, B; Morgan, SG; Oberlander, TF; Smolina, K, 2016) |
| "The safety of domperidone in pregnancy remains unknown." | 7.79 | Fetal and neonatal outcomes in women taking domperidone during pregnancy. ( Ahn, HK; Choi, JS; Han, JY; Kim, MY; Koren, G; Nava-Ocampo, AA; Ryu, HM; Yang, JH, 2013) |
| "The influence of Motilium (domperidone) tablet on the increase of human prolactin level was investigated in the first and second trimester of pregnancy, in confinement and menopause." | 7.68 | [Clinico-pharmacological investigation of drugs (domperidone, bromocriptine) influencing human prolactin levels from pregnancy to menopause]. ( Farkas, M, 1993) |
| "On d 90 of gestation, gilts received daily injections of (1) canola oil until d 109 ± 1 of gestation (CTL, n = 18); (2) domperidone (to induce hyperprolactinemia) until d 96 ± 1 of gestation (T7, n = 17) or; (3) domperidone (until d 109 ± 1 of gestation (T20, n = 17)." | 4.31 | Effects of sustained hyperprolactinemia in late gestation on the mammary parenchymal tissue transcriptome of gilts. ( Caron, A; Farmer, C; Palin, MF, 2023) |
| "Domperidone is widely used during pregnancy, although the risks associated with pregnant women have not been adequately evaluated." | 4.02 | Risk of Pregnancy Termination and Congenital Anomalies After Domperidone Exposure: A Study in the EFEMERIS Database. ( Araujo, M; Benevent, J; Damase-Michel, C; Hurault-Delarue, C; Lacroix, I; Sommet, A; Vabre, C, 2021) |
| "Objectives of this experiment were to determine if the domperidone protocol previously used for gestating gilts can also lead to hyperprolactinemia in growing gilts, and to assess the effects of such a protocol on hormonal status, mammary development and gene expression in mammary and pituitary tissue of gilts at puberty." | 4.02 | Hyperprolactinemia using domperidone in prepubertal gilts: Effects on hormonal status, mammary development and mammary and pituitary gene expression. ( Farmer, C; Palin, MF, 2021) |
| " The dopamine receptor antagonist domperidone can increase circulating prolactin concentrations in pigs, but the ideal dose to achieve sustained hyperprolactinemia remains unknown." | 3.91 | Using domperidone to induce and sustain hyperprolactinemia in late-pregnant gilts. ( Farmer, C; Hovey, RC; Mathews, AT, 2019) |
| "The aim of this study is to examine the relationship between domperidone (commonly used off-label for lactation stimulation), ventricular arrhythmia and all-cause mortality during the postpartum period." | 3.83 | The association between domperidone and ventricular arrhythmia in the postpartum period. ( Hanley, GE; Mintzes, B; Morgan, SG; Oberlander, TF; Smolina, K, 2016) |
| "The safety of domperidone in pregnancy remains unknown." | 3.79 | Fetal and neonatal outcomes in women taking domperidone during pregnancy. ( Ahn, HK; Choi, JS; Han, JY; Kim, MY; Koren, G; Nava-Ocampo, AA; Ryu, HM; Yang, JH, 2013) |
| " We hypothesized that inducing hyperprolactinemia in primiparous gilts during late gestation by administering the dopamine antagonist domperidone (DOM) would increase MG epithelial cell proliferation and differentiation, subsequent milk yield, and piglet growth." | 3.79 | Late gestational hyperprolactinemia accelerates mammary epithelial cell differentiation that leads to increased milk yield. ( Hovey, RC; Manjarin, R; McMicking, HF; Trott, JF; Vanklompenberg, MK, 2013) |
| "1 mg of domperidone/kg of body weight/d; and 3." | 3.69 | Efficacy of domperidone and sulpiride as treatments for fescue toxicosis in horses. ( Cross, DL; Kennedy, SW; Redmond, LM; Strickland, JR, 1994) |
| "We have explored temporal changes in the magnitude of dopamine (DA) interaction (DA tone) at the anterior pituitary lactotrophs related to both the nocturnal and diurnal prolactin (PRL) surges on day 8 of pregnancy, by utilizing a competitive DA D2 antagonist, domperidone (DOM)." | 3.68 | Differential regulation of the nocturnal and diurnal prolactin surges in pregnant rats revealed by dopamine receptor antagonism. ( Mathiasen, JR; Voogt, JL, 1992) |
| "The incidence of dyspepsias and emesis occurring either as accompanying symptoms of gynaecological operations or as independent clinical conditions, therapeutic means for controlling these conditions and the mechanism of action and clinical usefulness of the dopamine antagonist domperidone have been discussed." | 3.67 | Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting. ( Sásdi, A, 1989) |
| " Hyperprolactinaemia produced by treatment with either dopamine antagonists (domperidone or haloperidol) or ovine prolactin was also associated with an impairment of the OT stress response in intact females, whereas domperidone treatment failed to modify the response in ovariectomized (OVX) rats." | 3.67 | Oxytocin responses to stress in lactating and hyperprolactinaemic rats. ( Carter, DA; Lightman, SL, 1987) |
| "Domperidone-treated gilts also received 100 mg of domperidone per os twice daily from days 90 to 93 of gestation." | 2.94 | Effects of sustained hyperprolactinemia in late gestation on mammary development of gilts. ( Caron, A; Cohen, J; Farmer, C; Hovey, RC; Laforest, JP; Palin, MF, 2020) |
| "To investigate the possibility of a dose-response relationship for the use of domperidone in treating insufficient milk supply in mothers of preterm infants, and to quantify the exposure of the breastfed infant to domperidone." | 2.73 | Dose-effect study of domperidone as a galactagogue in preterm mothers with insufficient milk supply, and its transfer into milk. ( Davey, K; Hartmann, PE; Ilett, KF; Page-Sharp, M; Simmer, K; Wan, EW, 2008) |
| "Migraine is a typical "women's disease": the fluctuations of sex hormones, in particular estrogens, during woman's reproductive life show a direct and major influence on migraine course." | 2.42 | [Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies]. ( Airola, G; Allais, G; Benedetto, C; Bosio, A; Ciochetto, D; De Lorenzo, C; Mana, O; Quirico, PE; Terzi, MG, 2003) |
| "Domperidone use was significantly higher in women who were primiparous, gave birth preterm, delivered by caesarean section, had self-perceived low milk supply, and saw a lactation consultant." | 1.91 | Women's experiences with using domperidone as a galactagogue to increase breast milk supply: an australian cross-sectional survey. ( Amir, LH; Grzeskowiak, LE; Keir, A; McBride, GM; Rumbold, AR; Stevenson, R; Zizzo, G, 2023) |
| "The pimozide-treated group showed high prolactin levels measured on day 23, at vaginal opening and at first oestrus." | 1.27 | Involvement of prolactin in the onset of puberty in female rats. ( Aguilar, E; Gonzalez, MD; López, F, 1984) |
| "Bromocriptine treatment in April (seasonal diapause) was followed by a significant reduction in prolactin concentrations and reduced growth rate of joeys belonging to treated females." | 1.27 | Effects of lactation and season on plasma prolactin concentrations and response to bromocriptine during lactation in the Bennett's wallaby (Macropus rufogriseus rufogriseus). ( Curlewis, JD; Loudon, AS; McNeilly, AS; White, AS, 1986) |
| " After a rapid initial decrease radioactivity was eliminated with a half-life of 8-10 hours." | 1.26 | On the pharmacokinetics of domperidone in animals and man II. Tissue distribution, placental and milk transfer of domperidone in the Wistar rat. ( Hendriks, R; Heykants, J; Michiels, M, 1981) |
| "Domperidone is a peripheral antagonist of dopamine which does not cross the blood-brain barrier." | 1.26 | [Domperidone: a new pharmacodynamic agent for exploration of the hypophysis (author's transl)]. ( Bercovici, JP; Besson, G; Caroff, J; Khoury, S; Sudre, Y; Tater, D, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (50.62) | 18.7374 |
| 1990's | 7 (8.64) | 18.2507 |
| 2000's | 5 (6.17) | 29.6817 |
| 2010's | 16 (19.75) | 24.3611 |
| 2020's | 12 (14.81) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, T | 1 |
| Obara, T | 1 |
| Akazawa, M | 1 |
| Noda, A | 1 |
| Oyanagi, G | 1 |
| Morishita, K | 1 |
| Miyakoda, K | 1 |
| Nishigori, H | 1 |
| Kawame, H | 1 |
| Yaegashi, N | 1 |
| Kuriyama, S | 1 |
| Mano, N | 1 |
| Saejueng, K | 1 |
| Nopsopon, T | 1 |
| Wuttikonsammakit, P | 1 |
| Khumbun, W | 1 |
| Pongpirul, K | 1 |
| Palin, MF | 5 |
| Caron, A | 2 |
| Farmer, C | 6 |
| McBride, GM | 1 |
| Stevenson, R | 1 |
| Zizzo, G | 1 |
| Rumbold, AR | 1 |
| Amir, LH | 1 |
| Keir, A | 1 |
| Grzeskowiak, LE | 2 |
| Archana, A | 1 |
| Adhisivam, B | 1 |
| Chaturvedula, L | 1 |
| Subramanian, S | 1 |
| Hovey, RC | 4 |
| Cohen, J | 1 |
| Laforest, JP | 1 |
| Hishinuma, K | 1 |
| Yamane, R | 1 |
| Yokoo, I | 1 |
| Arimoto, T | 1 |
| Takahashi, K | 1 |
| Goto, M | 1 |
| Saito, Y | 1 |
| Nakajima, K | 1 |
| Murashima, A | 1 |
| Hayashi, M | 1 |
| Hurault-Delarue, C | 2 |
| Araujo, M | 2 |
| Vabre, C | 2 |
| Benevent, J | 2 |
| Damase-Michel, C | 2 |
| Lacroix, I | 2 |
| Sommet, A | 1 |
| Mathews, AT | 1 |
| Lacasse, P | 1 |
| Zhao, X | 1 |
| Ollier, S | 1 |
| Choi, JS | 1 |
| Han, JY | 1 |
| Ahn, HK | 1 |
| Ryu, HM | 1 |
| Kim, MY | 1 |
| Yang, JH | 1 |
| Nava-Ocampo, AA | 1 |
| Koren, G | 1 |
| Carvalho-Freitas, MI | 2 |
| Anselmo-Franci, JA | 2 |
| Palermo-Neto, J | 2 |
| Felicio, LF | 2 |
| Furyk, JS | 1 |
| Meek, R | 1 |
| McKenzie, S | 1 |
| Axelsson, PB | 1 |
| Bjerrum, F | 1 |
| Løkkegaard, EC | 1 |
| Dalton, JA | 1 |
| Fielder, AL | 1 |
| VanKlompenberg, MK | 2 |
| Manjarín, R | 2 |
| Donovan, CE | 1 |
| Trott, JF | 2 |
| Smolina, K | 1 |
| Mintzes, B | 1 |
| Hanley, GE | 1 |
| Oberlander, TF | 1 |
| Morgan, SG | 1 |
| Wan, EW | 1 |
| Davey, K | 1 |
| Page-Sharp, M | 1 |
| Hartmann, PE | 1 |
| Simmer, K | 1 |
| Ilett, KF | 1 |
| Mari, G | 1 |
| Morganti, M | 1 |
| Merlo, B | 1 |
| Castagnetti, C | 1 |
| Parmeggiani, F | 1 |
| Govoni, N | 1 |
| Galeati, G | 1 |
| Tamanini, C | 1 |
| Campbell-Yeo, ML | 1 |
| Allen, AC | 1 |
| Joseph, KS | 1 |
| Ledwidge, JM | 1 |
| Caddell, K | 1 |
| Allen, VM | 1 |
| Dooley, KC | 1 |
| Maiorka, PC | 1 |
| Festin, M | 1 |
| Duran, MS | 1 |
| Spatz, DL | 1 |
| Jantarasaengaram, S | 1 |
| Sreewapa, P | 1 |
| Cross, DL | 3 |
| Reinemeyer, CR | 1 |
| Prado, JC | 1 |
| Donnell, RL | 1 |
| Bond, KG | 1 |
| Farr, H | 1 |
| Longhofer, SL | 1 |
| McMicking, HF | 1 |
| Allais, G | 1 |
| Bosio, A | 1 |
| Mana, O | 1 |
| Airola, G | 1 |
| Ciochetto, D | 1 |
| Terzi, MG | 1 |
| De Lorenzo, C | 1 |
| Quirico, PE | 1 |
| Benedetto, C | 1 |
| Andrews, ZB | 1 |
| Grattan, DR | 1 |
| van der Steen, M | 1 |
| Du Caju, MV | 1 |
| Van Acker, KJ | 1 |
| Hofmeyr, GJ | 2 |
| van Iddekinge, B | 2 |
| Guldager, H | 1 |
| Jensen, FM | 1 |
| Andersen, KH | 1 |
| Arnfred, I | 1 |
| Levin, G | 1 |
| Fisher, RS | 1 |
| Cann, PA | 1 |
| Read, NW | 1 |
| Holdsworth, CD | 1 |
| Camanni, F | 6 |
| Ghigo, E | 3 |
| Ciccarelli, E | 3 |
| Massara, F | 4 |
| Campagnoli, C | 1 |
| Molinatti, G | 1 |
| Müller, EE | 6 |
| Gonzalez, MD | 1 |
| López, F | 1 |
| Aguilar, E | 1 |
| Hansen, S | 2 |
| Södersten, P | 5 |
| Eneroth, P | 5 |
| Maddern, GJ | 1 |
| Martra, M | 1 |
| Dolfin, GC | 1 |
| Molinatti, GM | 3 |
| Lomas, DE | 1 |
| Keverne, EB | 1 |
| Santià, M | 1 |
| Genazzani, AR | 3 |
| De Leo, V | 3 |
| Michiels, M | 1 |
| Hendriks, R | 1 |
| Heykants, J | 1 |
| Bercovici, JP | 1 |
| Khoury, S | 1 |
| Tater, D | 1 |
| Caroff, J | 1 |
| Sudre, Y | 1 |
| Besson, G | 1 |
| Downing, JW | 2 |
| Brock-Utne, JG | 2 |
| Mankowitz, E | 1 |
| Dimopoulos, GE | 1 |
| Rubin, J | 1 |
| Moshal, MG | 1 |
| Redmond, LM | 2 |
| Strickland, JR | 2 |
| Cecim, M | 1 |
| Fadden, C | 1 |
| Kerr, J | 1 |
| Steger, RW | 1 |
| Bartke, A | 1 |
| Kennedy, SW | 1 |
| Farkas, M | 1 |
| O'Brien, GM | 1 |
| Curlewis, JD | 3 |
| Martin, L | 1 |
| Mathiasen, JR | 1 |
| Voogt, JL | 1 |
| Miola, C | 1 |
| Gandini, G | 1 |
| Rolfini, G | 1 |
| De Rosa, D | 1 |
| Lupi, AM | 1 |
| Petrelli, V | 1 |
| Sásdi, A | 1 |
| Forsberg, G | 2 |
| Haisenleder, DJ | 2 |
| Gala, RR | 2 |
| Lawson, DM | 2 |
| Moy, JA | 1 |
| Crowley, WR | 1 |
| Shyr, SW | 2 |
| Kacsoh, B | 1 |
| Grosvenor, CE | 3 |
| Sondervan-Frank, BS | 2 |
| Loudon, AS | 2 |
| Ravindra, R | 1 |
| Fabri, M | 1 |
| Nazzicone, Q | 1 |
| Galanti, A | 1 |
| Maselli, G | 1 |
| Nappi, C | 1 |
| Colace, G | 1 |
| Di Renzo, GF | 1 |
| Taglialatela, M | 1 |
| Amoroso, S | 1 |
| Annunziato, L | 1 |
| Montemagno, U | 1 |
| Carter, DA | 1 |
| Lightman, SL | 1 |
| Petraglia, F | 2 |
| Sardelli, S | 2 |
| Pieroni, ML | 2 |
| Bruno, G | 1 |
| Gioffrè, WR | 1 |
| D'Antona, N | 2 |
| White, AS | 1 |
| McNeilly, AS | 1 |
| Blott, JA | 1 |
| Waldmann, CS | 1 |
| Verghese, C | 1 |
| Short, SM | 1 |
| Goldhill, DR | 1 |
| Evans, SJ | 1 |
| Johnston, DG | 1 |
| Haigh, J | 1 |
| Prescott, RW | 1 |
| Heaton, A | 1 |
| Kendall-Taylor, P | 1 |
| Baylis, P | 1 |
| Alberti, KG | 1 |
| Rowe, R | 1 |
| Friesen, H | 1 |
| Cook, D | 1 |
| Novelli, A | 1 |
| Massobrio, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Clinical Trial: Use of Domperidone to Increase Milk Production in Mothers With Newborns Hospitalized in Neonatology[NCT03221855] | Early Phase 1 | 30 participants (Actual) | Interventional | 2013-03-31 | Completed | ||
| A Double Blind Placebo Controlled Trial Examining the Effect of Domperidone on the Composition of Breast Milk[NCT00308334] | Phase 2/Phase 3 | 46 participants (Actual) | Interventional | 2003-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for domperidone and Pregnancy
| Article | Year |
|---|---|
[Pharmaceutical treatment of lactation deficiency lacks evidence].
Topics: Breast Feeding; Domperidone; Dopamine Antagonists; Evidence-Based Medicine; Female; Humans; Lactatio | 2014 |
Nausea and vomiting in early pregnancy.
Topics: Acupressure; Administration, Oral; Domperidone; Female; Humans; Metoclopramide; Nausea; Phytotherapy | 2009 |
[Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies].
Topics: Abnormalities, Drug-Induced; Acetaminophen; Acupuncture Points; Acupuncture Therapy; Adult; Analgesi | 2003 |
Gastroesophageal reflux disease: an update.
Topics: Antacids; Anti-Ulcer Agents; Bethanechol Compounds; Domperidone; Female; Gastroesophageal Reflux; Hu | 1983 |
Equine fescue toxicosis: signs and solutions.
Topics: Acremonium; Animal Feed; Animals; Body Temperature; Domperidone; Ergot Alkaloids; Ergotism; Estradio | 1995 |
14 trials available for domperidone and Pregnancy
| Article | Year |
|---|---|
Efficacy of Wang Nam Yen herbal tea on human milk production: A randomized controlled trial.
Topics: Adolescent; Adult; Cesarean Section; Domperidone; Female; Galactogogues; Humans; Lactation; Milk, Hu | 2022 |
Oral domperidone versus placebo for enhancing exclusive breastfeeding among post-lower segment cesarean section mothers - a double-blind randomized controlled trial.
Topics: Breast Feeding; Cesarean Section; Cognition; Domperidone; Female; Humans; Infant; Lactation; Pregnan | 2023 |
Effects of sustained hyperprolactinemia in late gestation on mammary development of gilts.
Topics: Animals; Domperidone; Dopamine Antagonists; Drug Administration Schedule; Female; Hyperprolactinemia | 2020 |
Dose-effect study of domperidone as a galactagogue in preterm mothers with insufficient milk supply, and its transfer into milk.
Topics: Breast Feeding; Clinical Protocols; Domperidone; Dopamine Antagonists; Dose-Response Relationship, D | 2008 |
Effect of domperidone on the composition of preterm human breast milk.
Topics: Administration, Oral; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Admi | 2010 |
Effect of domperidone on the composition of preterm human breast milk.
Topics: Administration, Oral; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Admi | 2010 |
Effect of domperidone on the composition of preterm human breast milk.
Topics: Administration, Oral; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Admi | 2010 |
Effect of domperidone on the composition of preterm human breast milk.
Topics: Administration, Oral; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Admi | 2010 |
Effects of domperidone on augmentation of lactation following cesarean delivery at full term.
Topics: Adult; Cesarean Section; Domperidone; Dopamine Antagonists; Double-Blind Method; Drug Administration | 2012 |
Efficacy of domperidone gel in an induced model of fescue toxicosis in periparturient mares.
Topics: Animals; Domperidone; Ergotamines; Ergotism; Female; Festuca; Gels; Gestational Age; Horse Diseases; | 2012 |
[Domperidone and metoclopramide in the prevention of postoperative nausea and vomiting].
Topics: Abortion, Induced; Adolescent; Adult; Clinical Trials as Topic; Domperidone; Double-Blind Method; Fe | 1983 |
Galactorrhoea as side effect of domperidone.
Topics: Adult; Domperidone; Female; Galactorrhea; Humans; Lactation Disorders; Middle Aged; Pregnancy; Prola | 1983 |
Domperidone antagonizes bromoergocriptine--induced nausea and vomiting without affecting its inhibition of prolactin secretion in puerperal women.
Topics: Adult; Bromocriptine; Domperidone; Drug Therapy, Combination; Female; Humans; Hyperprolactinemia; Na | 1987 |
[Use of domperidone in the induction and maintenance of maternal breast feeding].
Topics: Breast Feeding; Domperidone; Female; Humans; Lactation; Pregnancy; Prolactin | 1986 |
Domperidone: secretion in breast milk and effect on puerperal prolactin levels.
Topics: Clinical Trials as Topic; Domperidone; Double-Blind Method; Female; Humans; Lactation; Milk, Human; | 1985 |
The evaluation of domperidone and metoclopramide as antiemetics in day care abortion patients.
Topics: Abortion, Therapeutic; Adolescent; Adult; Anesthesia, General; Anesthesia, Obstetrical; Clinical Tri | 1985 |
Domperidone in defective and insufficient lactation.
Topics: Adult; Clinical Trials as Topic; Domperidone; Double-Blind Method; Female; Humans; Lactation Disorde | 1985 |
62 other studies available for domperidone and Pregnancy
| Article | Year |
|---|---|
Risk of major congenital malformations associated with first-trimester exposure to propulsives: A health administrative database study in Japan.
Topics: Abnormalities, Drug-Induced; Databases, Factual; Domperidone; Female; Gastrointestinal Agents; Human | 2022 |
Effects of sustained hyperprolactinemia in late gestation on the mammary parenchymal tissue transcriptome of gilts.
Topics: Animals; Domperidone; Female; Hyperprolactinemia; Lactation; Mammary Glands, Animal; Parenchymal Tis | 2023 |
Women's experiences with using domperidone as a galactagogue to increase breast milk supply: an australian cross-sectional survey.
Topics: Australia; Breast Feeding; Cesarean Section; Cross-Sectional Studies; Domperidone; Dopamine Antagoni | 2023 |
Oral administration of domperidone in the first or third week of lactation: Effects on prolactin concentrations and mammary gene expression in sows and piglet growth.
Topics: Administration, Oral; Animal Feed; Animals; Domperidone; Female; Gene Expression; Lactation; Pregnan | 2023 |
Pregnancy outcome after first trimester exposure to domperidone-An observational cohort study.
Topics: Cohort Studies; Domperidone; Female; Humans; Metoclopramide; Pregnancy; Pregnancy Outcome; Pregnancy | 2021 |
What changes in prescription patterns of antiemetic medications in pregnant women in France?
Topics: Antiemetics; Domperidone; Drug Prescriptions; Female; France; Humans; Pregnancy; Pregnant Women | 2021 |
Risk of Pregnancy Termination and Congenital Anomalies After Domperidone Exposure: A Study in the EFEMERIS Database.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Domperidone; Female; Humans; Infant, Newborn; Pregna | 2021 |
Hyperprolactinemia using domperidone in prepubertal gilts: Effects on hormonal status, mammary development and mammary and pituitary gene expression.
Topics: Animals; Domperidone; Female; Gene Expression; Hyperprolactinemia; Lactation; Mammary Glands, Animal | 2021 |
Providing domperidone throughout lactation enhances sow lactation performance.
Topics: Animals; Diet; Domperidone; Female; Lactation; Milk; Pregnancy; Swine; Weaning | 2021 |
Using domperidone to induce and sustain hyperprolactinemia in late-pregnant gilts.
Topics: Animals; Domperidone; Dose-Response Relationship, Drug; Emulsions; Female; Gestational Age; Hyperpro | 2019 |
Effect of stage of lactation and gestation on milking-induced hormone release in lactating dairy cows.
Topics: Animals; beta-Endorphin; Cattle; Dairying; Domperidone; Dopamine Antagonists; Female; Gestational Ag | 2019 |
Fetal and neonatal outcomes in women taking domperidone during pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Antiemetics; Birth Weight; Domperidone; Female; Fetal Developmen | 2013 |
Prior reproductive experience alters prolactin-induced macrophage responses in pregnant rats.
Topics: Animals; Cells, Cultured; Domperidone; Dopamine D2 Receptor Antagonists; Female; Gravidity; Macropha | 2013 |
Drug treatment of adults with nausea and vomiting in primary care.
Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopra | 2014 |
Factors associated with domperidone use as a galactogogue at an Australian tertiary teaching hospital.
Topics: Adult; Australia; Birth Weight; Breast Feeding; Cohort Studies; Domperidone; Dopamine Antagonists; D | 2015 |
Regulation and localization of vascular endothelial growth factor within the mammary glands during the transition from late gestation to lactation.
Topics: Angiogenesis Inducing Agents; Animals; Aquaporins; Colostrum; Domperidone; Female; Gene Expression; | 2016 |
Domperidone: do not use during pregnancy.
Topics: Antipsychotic Agents; Death, Sudden; Domperidone; Female; Fetus; Heart; Humans; Pregnancy | 2015 |
The association between domperidone and ventricular arrhythmia in the postpartum period.
Topics: Adult; Arrhythmias, Cardiac; British Columbia; Cohort Studies; Domperidone; Dopamine Antagonists; Fe | 2016 |
Administration of sulpiride or domperidone for advancing the first ovulation in deep anestrous mares.
Topics: Anestrus; Animals; Domperidone; Female; Horses; Insemination, Artificial; Luteinizing Hormone; Ovula | 2009 |
Prolactin differentially modulates the macrophage activity of lactating rats: possible role of reproductive experience.
Topics: Animals; Cells, Cultured; Domperidone; Dopamine Antagonists; Female; Lactation; Macrophage Activatio | 2011 |
A mother with glandular hypoplasia and a late preterm infant.
Topics: Adult; Breast; Breast Feeding; Domperidone; Dopamine Antagonists; Female; Humans; Infant, Newborn; I | 2011 |
Late gestational hyperprolactinemia accelerates mammary epithelial cell differentiation that leads to increased milk yield.
Topics: Animals; Cell Differentiation; Cell Proliferation; Domperidone; Dopamine Antagonists; Epithelial Cel | 2013 |
The roles of dopamine and the neurointermediate lobe of the pituitary in the regulation of prolactin secretion during late pregnancy in rats.
Topics: Animals; Domperidone; Dopamine; Dopamine Antagonists; Drinking; Female; Litter Size; Parturition; Pi | 2004 |
Gynecomastia in a male infant given domperidone.
Topics: Domperidone; Female; Galactorrhea; Gynecomastia; Humans; Infant; Male; Pregnancy; Vomiting | 1982 |
Domperidone and lactation.
Topics: Domperidone; Female; Humans; Lactation; Pregnancy; Stimulation, Chemical | 1983 |
Defective regulation of prolactin secretion after successful removal of prolactinomas.
Topics: Adenoma; Adult; Domperidone; Female; Humans; Male; Nomifensine; Pituitary Neoplasms; Pregnancy; Prol | 1983 |
Involvement of prolactin in the onset of puberty in female rats.
Topics: Adrenal Glands; Animals; Body Weight; Bromocriptine; Domperidone; Estrus; Female; Luteinizing Hormon | 1984 |
Mechanisms regulating hormone release and the duration of dioestrus in the lactating rat.
Topics: Animals; Bromocriptine; Diestrus; Domperidone; Estrus; Female; Lactation; Luteinizing Hormone; Pregn | 1983 |
Inhibition of sexual behaviour in lactating rats.
Topics: Animals; Bromocriptine; Castration; Dihydrotestosterone; Domperidone; Estradiol; Female; Lactation; | 1983 |
Galactorrhoea due to domperidone.
Topics: Adult; Domperidone; Female; Galactorrhea; Gastroesophageal Reflux; Humans; Lactation Disorders; Preg | 1983 |
Suckling and serum prolactin and LH concentrations in lactating rats.
Topics: Animals; Domperidone; Female; Lactation; Luteinizing Hormone; Pregnancy; Prolactin; Rats; Rats, Inbr | 1984 |
Reciprocal pattern of the TSH and PRL responses to dopamine receptor blockade in women with physiological or pathological hyperprolactinaemia.
Topics: Adolescent; Adult; Domperidone; Female; Humans; Pituitary Neoplasms; Postpartum Period; Pregnancy; P | 1983 |
Role of the vomeronasal organ and prolactin in the acceleration of puberty in female mice.
Topics: Animals; Bromocriptine; Domperidone; Estrus; Female; Mice; Mice, Inbred Strains; Nasal Septum; Phero | 1982 |
Impaired prolactin responsiveness to dopamine antagonists in acromegaly.
Topics: Acromegaly; Adolescent; Adult; Domperidone; Dopamine Antagonists; Female; Growth Hormone; Humans; Ma | 1982 |
Tests of prolactin secretion in the diagnosis of hyperprolactinemic states: nomifensine and domperidone.
Topics: Adenoma; Adult; Benzimidazoles; Domperidone; Female; Humans; Isoquinolines; Male; Menstruation; Midd | 1981 |
On the pharmacokinetics of domperidone in animals and man II. Tissue distribution, placental and milk transfer of domperidone in the Wistar rat.
Topics: Administration, Oral; Animals; Antiemetics; Benzimidazoles; Domperidone; Female; Injections, Intrave | 1981 |
[Domperidone: a new pharmacodynamic agent for exploration of the hypophysis (author's transl)].
Topics: Benzimidazoles; Domperidone; Female; Growth Hormone; Humans; Male; Piperidines; Pituitary Diseases; | 1981 |
Two new drugs improve anesthetic management in obstetrics.
Topics: Anesthesia, Obstetrical; Benzimidazoles; Domperidone; Etomidate; Female; Humans; Imidazoles; Piperid | 1981 |
Effect of domperidone on lower esophageal sphincter tone in late pregnancy.
Topics: Adolescent; Adult; Anesthesia, Obstetrical; Benzimidazoles; Domperidone; Esophagogastric Junction; F | 1980 |
Infertility in transgenic mice overexpressing the bovine growth hormone gene: disruption of the neuroendocrine control of prolactin secretion during pregnancy.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Cattle; Domperidone; Dop | 1995 |
Efficacy of domperidone and sulpiride as treatments for fescue toxicosis in horses.
Topics: Animal Feed; Animals; Animals, Newborn; Body Weight; Domperidone; Estradiol; Female; Foodborne Disea | 1994 |
[Clinico-pharmacological investigation of drugs (domperidone, bromocriptine) influencing human prolactin levels from pregnancy to menopause].
Topics: Bromocriptine; Domperidone; Estradiol; Female; Follicle Stimulating Hormone; Humans; Labor, Obstetri | 1993 |
A heterologous assay for measuring prolactin in pituitary extracts and plasma from Australian flying foxes (genus Pteropus).
Topics: Animals; Bromocriptine; Chiroptera; Domperidone; Dopamine Agonists; Dopamine Antagonists; Female; La | 1996 |
Differential regulation of the nocturnal and diurnal prolactin surges in pregnant rats revealed by dopamine receptor antagonism.
Topics: Animals; Circadian Rhythm; Domperidone; Dopamine D2 Receptor Antagonists; Female; Kinetics; Pregnanc | 1992 |
Long-term follow-up of 'cured' prolactinoma patients after successful adenomectomy.
Topics: Adenoma; Adrenalectomy; Adult; Domperidone; Dopamine Antagonists; Female; Follow-Up Studies; Humans; | 1990 |
[Hypogalactia: therapeutic possibilities].
Topics: Administration, Oral; Adult; Domperidone; Female; Humans; Lactation; Lactation Disorders; Metoclopra | 1989 |
Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting.
Topics: Adolescent; Adult; Aged; Domperidone; Dyspepsia; Female; Genital Diseases, Female; Humans; Hyperemes | 1989 |
Naloxone stimulates sexual behaviour in lactating rats.
Topics: Adrenalectomy; Animals; beta-Endorphin; Cervix Uteri; Domperidone; Endorphins; Estradiol; Female; La | 1987 |
A comparison of the effects of suckling or transient dopamine antagonism on thyrotropin-releasing hormone and suckling induced prolactin release in lactating rats.
Topics: Animals; Domperidone; Dopamine Antagonists; Ergolines; Female; Lactation; Physical Stimulation; Preg | 1986 |
The effect of transient dopamine antagonism on thyrotropin-releasing hormone-induced prolactin release in pregnant rats.
Topics: Animals; Bromocriptine; Domperidone; Dopamine Antagonists; Female; Pituitary Gland, Anterior; Pregna | 1986 |
Evidence for stimulatory noradrenergic and inhibitory dopaminergic regulation of oxytocin release in the lactating rat.
Topics: Animals; Bromocriptine; Domperidone; Dopamine; Female; Hydroxydopamines; Hypothalamus; Kinetics; Lac | 1987 |
[Promoting lactation with the aid of drugs].
Topics: Chlorpromazine; Cimetidine; Domperidone; Female; Humans; Lactation; Medroxyprogesterone; Metoclopram | 1987 |
Experimental manipulations of prolactin following removal of pouch young or bromocriptine treatment during lactational quiescence in the Bennett's wallaby.
Topics: Animals; Bromocriptine; Domperidone; Female; Lactation; Macropodidae; Marsupialia; Pregnancy; Proges | 1988 |
Soluble and polymerized tubulin levels in the anterior pituitary lobe of the lactating rat during suckling.
Topics: Animals; Bromocriptine; Colchicine; Domperidone; Female; Kinetics; Lactation; Macromolecular Substan | 1988 |
[Use of estrogens in post-coital contraception. Our case material of 243 cases].
Topics: Adolescent; Adult; Contraceptives, Postcoital; Contraceptives, Postcoital, Hormonal; Domperidone; Es | 1988 |
[Promotion of lactation with pharmaceutic agents].
Topics: Chemical Phenomena; Chemistry; Domperidone; Female; Humans; Lactation; Pregnancy | 1987 |
Oxytocin responses to stress in lactating and hyperprolactinaemic rats.
Topics: Animals; Domperidone; Estradiol; Female; Haloperidol; Hyperprolactinemia; Lactation; Oxytocin; Pregn | 1987 |
Effects of lactation and season on plasma prolactin concentrations and response to bromocriptine during lactation in the Bennett's wallaby (Macropus rufogriseus rufogriseus).
Topics: Animals; Bromocriptine; Domperidone; Embryo Implantation, Delayed; Female; Lactation; Macropodidae; | 1986 |
Histidyl-proline-diketopiperazine (cyclo-his-pro) inhibits the suckling- and domperidone-induced transformation of prolactin in the lactating rat.
Topics: Animals; Domperidone; Dopamine; Female; Lactation; Peptides, Cyclic; Piperazines; Pituitary Gland, A | 1985 |
Prolactin secretion and biological activity in females with galactorrhoea and normal circulating prolactin concentrations at rest.
Topics: Adult; Animals; Biological Assay; Domperidone; Female; Galactorrhea; Humans; Insulin; Lactation Diso | 1985 |
Prolactin and thyrotropin response to blockade of dopamine synthesis by monoiodotyrosine in subjects with postpartum and pathological hyperprolactinemia.
Topics: Adenoma; Adult; Animals; Binding, Competitive; Domperidone; Dopamine; Female; Humans; In Vitro Techn | 1985 |
Role of the uterine cervix in inhibition of sexual behaviour in lactating rats.
Topics: Anesthesia, Local; Animals; Castration; Cervix Uteri; Domperidone; Estradiol; Female; Lactation; Phy | 1985 |