domperidone has been researched along with Postoperative Complications in 27 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind comparison of domperidone 10 mg, domperidone 4 mg, metoclopramide 10 mg and a placebo, 176 adult patients were given an intravenous injection of one of these substances after postoperative vomiting had occurred." | 9.05 | Postoperative vomiting treated with domperidone. A double-blind comparison with metoclopramide and a placebo. ( Boghaert, A; Carron, D; Gallant, J; Stockman, A, 1980) |
| " We wanted to study the effects of the new antiemetic Domperidone on vomiting after either anesthesia." | 9.05 | [Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)]. ( Alon, E; Axhausen, C; Bernoulli, L; Caluori, R; Hossli, G, 1982) |
| "Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone." | 7.68 | The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting. ( Lencz, L, 1990) |
| "Droperidol was significantly more effective than domperidone, metoclopramide or placebo in reducing emetic sequelae." | 6.66 | Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery. ( Madej, TH; Simpson, KH, 1986) |
| "In a double-blind comparison of domperidone 10 mg, domperidone 4 mg, metoclopramide 10 mg and a placebo, 176 adult patients were given an intravenous injection of one of these substances after postoperative vomiting had occurred." | 5.05 | Postoperative vomiting treated with domperidone. A double-blind comparison with metoclopramide and a placebo. ( Boghaert, A; Carron, D; Gallant, J; Stockman, A, 1980) |
| " We wanted to study the effects of the new antiemetic Domperidone on vomiting after either anesthesia." | 5.05 | [Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)]. ( Alon, E; Axhausen, C; Bernoulli, L; Caluori, R; Hossli, G, 1982) |
| " These pharmacological differences have clinical relevance: metoclopramide and domperidon could not consistently prove efficacy in functional dyspepsia and GORD." | 4.79 | [Pharmacologic and clinical differentiation of prokinetic drugs]. ( Greving, I; May, B, 1996) |
| "Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone." | 3.68 | The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting. ( Lencz, L, 1990) |
| "The incidence of dyspepsias and emesis occurring either as accompanying symptoms of gynaecological operations or as independent clinical conditions, therapeutic means for controlling these conditions and the mechanism of action and clinical usefulness of the dopamine antagonist domperidone have been discussed." | 3.67 | Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting. ( Sásdi, A, 1989) |
| "The administration of alfentanil by continuous infusion as supplementation to nitrous oxide for shortlasting anesthesias has been studied in 51 patients." | 3.66 | Continuous infusion of alfentanil. ( Booij, LH; Pelgrom, R; Steegers, PA, 1982) |
| "Droperidol was significantly more effective than domperidone, metoclopramide or placebo in reducing emetic sequelae." | 2.66 | Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery. ( Madej, TH; Simpson, KH, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (62.96) | 18.7374 |
| 1990's | 4 (14.81) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Heidinger, M | 1 |
| Gorkiewicz, G | 1 |
| Freisinger, O | 1 |
| Brcic, I | 1 |
| Zhang, XF | 1 |
| Yin, GZ | 1 |
| Liu, QG | 1 |
| Liu, XM | 1 |
| Wang, B | 1 |
| Yu, L | 1 |
| Liu, SN | 1 |
| Cui, HY | 1 |
| Lv, Y | 1 |
| Nantasupha, C | 1 |
| Ruengkhachorn, I | 1 |
| Ruangvutilert, P | 1 |
| Muresan, M | 1 |
| Young, P | 1 |
| Finn, BC | 1 |
| Bruetman, JE | 1 |
| Trimarchi, H | 1 |
| Nasr, VG | 1 |
| Bitar, MA | 1 |
| Chehade, JM | 1 |
| Dagher, WI | 1 |
| Baraka, AS | 1 |
| Palazzo, MG | 1 |
| Strunin, L | 1 |
| Guldager, H | 1 |
| Jensen, FM | 1 |
| Andersen, KH | 1 |
| Arnfred, I | 1 |
| Spelina, KR | 1 |
| Gerber, HR | 1 |
| Pagels, IL | 1 |
| Schneider, JA | 1 |
| Bauer, H | 1 |
| Doenicke, A | 1 |
| Steegers, PA | 1 |
| Booij, LH | 1 |
| Pelgrom, R | 1 |
| Boghaert, A | 1 |
| Carron, D | 1 |
| Gallant, J | 1 |
| Stockman, A | 1 |
| van Leeuwen, L | 2 |
| Helmers, JH | 2 |
| Minobe, T | 1 |
| Sekine, H | 1 |
| Torii, T | 1 |
| Fujiya, T | 1 |
| Ohtomo, Y | 1 |
| Alon, E | 1 |
| Caluori, R | 1 |
| Bernoulli, L | 1 |
| Axhausen, C | 1 |
| Hossli, G | 1 |
| May, B | 1 |
| Greving, I | 1 |
| Gerring, EL | 1 |
| King, JN | 1 |
| Jian, R | 1 |
| Varga, A | 1 |
| Lovas, J | 1 |
| Lencz, L | 1 |
| Sásdi, A | 1 |
| Madej, TH | 2 |
| Simpson, KH | 2 |
| Takács, G | 1 |
| Horváth, I | 1 |
| Waldmann, CS | 1 |
| Verghese, C | 1 |
| Short, SM | 1 |
| Goldhill, DR | 1 |
| Evans, SJ | 1 |
4 reviews available for domperidone and Postoperative Complications
| Article | Year |
|---|---|
[Gastroesophageal reflux as a cause of night sweating].
Topics: Adult; Aged; Anti-Ulcer Agents; Cholestyramine Resin; Diagnosis, Differential; Domperidone; Female; | 2007 |
Anaesthesia and emesis. II: Prevention and management.
Topics: Anesthesia; Antiemetics; Butyrophenones; Domperidone; Histamine H1 Antagonists; Humans; Metocloprami | 1984 |
[Pharmacologic and clinical differentiation of prokinetic drugs].
Topics: Adult; Antiemetics; Child; Cisapride; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; D | 1996 |
[Disorders of gastric emptying].
Topics: Cisapride; Diabetes Complications; Domperidone; Dyspepsia; Gastric Emptying; Gastroesophageal Reflux | 1992 |
13 trials available for domperidone and Postoperative Complications
| Article | Year |
|---|---|
Effect of conventional diet schedule, early feeding and early feeding plus domperidone on postcesarean diet tolerance: A randomized controlled trial.
Topics: Adult; Antiemetics; Cesarean Section; Diet; Domperidone; Feeding Behavior; Female; Humans; Ileus; Po | 2016 |
[Domperidone and metoclopramide in the prevention of postoperative nausea and vomiting].
Topics: Abortion, Induced; Adolescent; Adult; Clinical Trials as Topic; Domperidone; Double-Blind Method; Fe | 1983 |
Nausea and vomiting during spinal anaesthesia. Effect of metoclopramide and domperidone: a double-blind trial.
Topics: Aged; Anesthesia, Spinal; Blood Pressure; Clinical Trials as Topic; Domperidone; Double-Blind Method | 1984 |
[Influence of domperidone and metoclopramide on serum gastrin levels and gastric acid secretion (author's transl)].
Topics: Adult; Antiemetics; Benzimidazoles; Domperidone; Gastric Acid; Gastrins; Gastrointestinal Motility; | 1981 |
Postoperative vomiting treated with domperidone. A double-blind comparison with metoclopramide and a placebo.
Topics: Adult; Aged; Antiemetics; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double-Blind Method | 1980 |
The efficacy of Domperidone (R 33812) in the treatment of postoperative vomiting. A double-blind study with a placebo.
Topics: Adolescent; Adult; Aged; Antiemetics; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double- | 1980 |
[The effect of domperidone in the prevention of nausea and vomiting during post-operative recovery period from anesthesia--a double blind study (author's transl)].
Topics: Adult; Anesthesia; Clinical Trials as Topic; Domperidone; Double-Blind Method; Female; Humans; Male; | 1981 |
[Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)].
Topics: Adult; Aged; Anesthesia; Domperidone; Ether; Ethyl Ethers; Female; Humans; Male; Middle Aged; Postop | 1982 |
Cisapride in the prophylaxis of equine post operative ileus.
Topics: Animals; Antiemetics; Cholinergic Agents; Cisapride; Domperidone; Dose-Response Relationship, Drug; | 1989 |
Domperidone (R 33 812) as an antiemetic in the treatment of postoperative vomiting. A double blind comparison between two different dosages (4 mg and 10 mg).
Topics: Adolescent; Adult; Aged; Antiemetics; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double- | 1979 |
Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery.
Topics: Abdomen; Adult; Antiemetics; Clinical Trials as Topic; Domperidone; Droperidol; Female; Humans; Hyst | 1986 |
Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following gynaecological surgery in day cases.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Antiemetics; Clinical Trials as Topic; Dila | 1986 |
The evaluation of domperidone and metoclopramide as antiemetics in day care abortion patients.
Topics: Abortion, Therapeutic; Adolescent; Adult; Anesthesia, General; Anesthesia, Obstetrical; Clinical Tri | 1985 |
10 other studies available for domperidone and Postoperative Complications
| Article | Year |
|---|---|
Ulcerative reflux esophagitis associated with Clostridium ventriculi following hiatoplasty - is antibiotic treatment necessary? A case report.
Topics: Aged; Anti-Bacterial Agents; Antiemetics; Clostridium; Clostridium Infections; Domperidone; Esophagi | 2020 |
Does Braun enteroenterostomy reduce delayed gastric emptying after pancreaticoduodenectomy?
Topics: Abdominal Abscess; Acupuncture; Anastomotic Leak; Antiemetics; Domperidone; Enterostomy; Erythromyci | 2014 |
Successful relactation--a case history.
Topics: Adrenal Cortex Hormones; Adult; Anti-Infective Agents; Breast Feeding; Breast Milk Expression; Careg | 2011 |
Postoperative severe uvular edema following tonsillectomy in a child with a history of obstructive sleep apnea.
Topics: Adenoids; Antiemetics; Catheter Ablation; Domperidone; Edema; Enzyme Inhibitors; Humans; Infant; Mal | 2008 |
Continuous infusion of alfentanil.
Topics: Adult; Alfentanil; Anesthesia; Blood Pressure; Domperidone; Droperidol; Female; Fentanyl; Heart Rate | 1982 |
Some possible gynaecological indications for peripheral antidopamine therapy.
Topics: Adult; Climacteric; Domperidone; Drug Evaluation; Dyspepsia; Female; Gastrointestinal Diseases; Huma | 1992 |
The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Dimenhydrinate; Domperidone; Femal | 1990 |
Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting.
Topics: Adolescent; Adult; Aged; Domperidone; Dyspepsia; Female; Genital Diseases, Female; Humans; Hyperemes | 1989 |
Effect of domperidone on postoperative vomiting and dyspepsia aggravated by operation.
Topics: Adult; Domperidone; Dyspepsia; Female; Humans; Middle Aged; Nausea; Postoperative Complications; Pre | 1988 |
Observations with dopamine antagonist domperidone (Motilium) in controlling postoperative dyspepsias and vomiting.
Topics: Abdomen; Adult; Aged; Domperidone; Dyspepsia; Female; Humans; Male; Middle Aged; Postoperative Compl | 1987 |