domperidone has been researched along with Pituitary Diseases in 5 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Pituitary Diseases: Disorders involving either the ADENOHYPOPHYSIS or the NEUROHYPOPHYSIS. These diseases usually manifest as hypersecretion or hyposecretion of PITUITARY HORMONES. Neoplastic pituitary masses can also cause compression of the OPTIC CHIASM and other adjacent structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifteen normal menstruating women in the early follicular phase of their menstrual cycle, fifteen patients with prolactin secreting adenomas, two patients with a suprahypophysial lesion and an hyperprolactinemia, underwent a dopamine infusion (4 micrograms/kg/mn for four hours and an orally administration of domperidone (40 mg)." | 3.66 | [Kinetics of prolactinemia after withdrawal of dopamine perfusion and during the administration of domperidone. Normal and hyperprolactinemic subjects (prolactinomas and suprahypophyseal lesions)]. ( Bercovici, JP; Besson, G; Caroff, J; Khoury, S; Tater, D, 1983) |
| "Domperidone is a peripheral antagonist of dopamine which does not cross the blood-brain barrier." | 1.26 | [Domperidone: a new pharmacodynamic agent for exploration of the hypophysis (author's transl)]. ( Bercovici, JP; Besson, G; Caroff, J; Khoury, S; Sudre, Y; Tater, D, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beech, J | 1 |
| McFarlane, D | 1 |
| Lindborg, S | 1 |
| Sojka, JE | 2 |
| Boston, RC | 1 |
| Miller, MA | 1 |
| Pardo, ID | 1 |
| Jackson, LP | 1 |
| Moore, GE | 1 |
| Bercovici, JP | 2 |
| Khoury, S | 2 |
| Tater, D | 2 |
| Besson, G | 2 |
| Caroff, J | 2 |
| Webb, CB | 1 |
| Thominet, JL | 1 |
| Barowsky, H | 1 |
| Berelowitz, M | 1 |
| Frohman, LA | 1 |
| Sudre, Y | 1 |
5 other studies available for domperidone and Pituitary Diseases
| Article | Year |
|---|---|
α-Melanocyte--stimulating hormone and adrenocorticotropin concentrations in response to thyrotropin-releasing hormone and comparison with adrenocorticotropin concentration after domperidone administration in healthy horses and horses with pituitary pars i
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Domperidone; Dopamine Antagonists; Hormones; Horse | 2011 |
Correlation of pituitary histomorphometry with adrenocorticotrophic hormone response to domperidone administration in the diagnosis of equine pituitary pars intermedia dysfunction.
Topics: Adrenocorticotropic Hormone; Animals; Domperidone; Dopamine Antagonists; Female; Horse Diseases; Hor | 2008 |
[Kinetics of prolactinemia after withdrawal of dopamine perfusion and during the administration of domperidone. Normal and hyperprolactinemic subjects (prolactinomas and suprahypophyseal lesions)].
Topics: Adenoma; Adult; Domperidone; Dopamine; Female; Follicular Phase; Humans; Kinetics; Pituitary Disease | 1983 |
Evidence for lactotroph dopamine resistance in idiopathic hyperprolactinemia.
Topics: Adult; Bromocriptine; Domperidone; Dopamine; Dopamine Antagonists; Drug Resistance; Female; Humans; | 1983 |
[Domperidone: a new pharmacodynamic agent for exploration of the hypophysis (author's transl)].
Topics: Benzimidazoles; Domperidone; Female; Growth Hormone; Humans; Male; Piperidines; Pituitary Diseases; | 1981 |