Page last updated: 2024-10-26

domperidone and Peptic Ulcer

domperidone has been researched along with Peptic Ulcer in 3 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Research Excerpts

ExcerptRelevanceReference
"Dyspepsia affects one in four Australians; of those who present in general practice, the majority will have functional or non-ulcer dyspepsia, with no structural explanation for their symptoms."2.39Modern management of dyspepsia. ( Talley, NJ, 1996)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Muraoka, T1
Talley, NJ1
Friedman, G1

Reviews

1 review available for domperidone and Peptic Ulcer

ArticleYear
Modern management of dyspepsia.
    Australian family physician, 1996, Volume: 25, Issue:1

    Topics: Adult; Aged; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bismuth; Child; C

1996

Other Studies

2 other studies available for domperidone and Peptic Ulcer

ArticleYear
[A study on the effects of clinical drugs on lower esophageal sphincter pressure. Particularly on the relation with clinical drugs].
    Nihon Ika Daigaku zasshi, 1983, Volume: 50, Issue:2

    Topics: Alkalies; Calcium Channel Blockers; Domperidone; Esophagitis; Esophagogastric Junction; Histamine H2

1983
New drugs in gastroenterology.
    The Mount Sinai journal of medicine, New York, 1985, Volume: 52, Issue:6

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antidiarrheals; Colit

1985