domperidone has been researched along with Parkinson Disease, Secondary in 4 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lisuride is a soluble ergolene derivative with endocrine effects similar to but more potent than those of bromocriptine." | 1.26 | Lisuride in parkinsonism. ( Marsden, CD; Parkes, JD; Schachter, M; Smith, B; Wilson, A, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grimes, JD | 1 |
| Magner, PO | 1 |
| Parkes, JD | 1 |
| Schachter, M | 1 |
| Marsden, CD | 2 |
| Smith, B | 1 |
| Wilson, A | 1 |
| Smith, L | 1 |
| De Salvia, M | 1 |
| Jenner, P | 1 |
| Micheli, F | 1 |
| Gatto, E | 1 |
| Fernández Pardal, M | 1 |
| Paradiso, G | 1 |
4 other studies available for domperidone and Parkinson Disease, Secondary
| Article | Year |
|---|---|
Safety of domperidone in metoclopramide-induced parkinsonism.
Topics: Domperidone; Female; Humans; Metoclopramide; Middle Aged; Parkinson Disease, Secondary | 1984 |
Lisuride in parkinsonism.
Topics: Administration, Oral; Aged; Benzimidazoles; Chorea; Domperidone; Dose-Response Relationship, Drug; D | 1981 |
An appraisal of the antiparkinsonian activity of piribedil in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Oral; Animals; Antiemetics; Antiparkin | 1996 |
[Domperidone and Parkinson disease].
Topics: Domperidone; Female; Humans; Hypotension, Orthostatic; Middle Aged; Parkinson Disease, Secondary | 1988 |