Page last updated: 2024-10-26

domperidone and Obsessive-Compulsive Disorder

domperidone has been researched along with Obsessive-Compulsive Disorder in 2 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.

Research Excerpts

ExcerptRelevanceReference
"In this report, we describe a case of domperidone withdrawal in a woman with a history of major depressive disorder and obsessive-compulsive disorder (OCD), who experienced a recurrence of these disorders after stopping domperidone."4.12Domperidone Withdrawal in a Nursing Female with Pre-existing Psychiatric Illness: A Case Report. ( Doobay, M; Sharma, S; Sharma, V, 2022)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Sharma, V1
Sharma, S1
Doobay, M1
Perreault, ML1
Seeman, P1
Szechtman, H1

Other Studies

2 other studies available for domperidone and Obsessive-Compulsive Disorder

ArticleYear
Domperidone Withdrawal in a Nursing Female with Pre-existing Psychiatric Illness: A Case Report.
    Current drug safety, 2022, Volume: 17, Issue:3

    Topics: Anxiety Disorders; Comorbidity; Depressive Disorder, Major; Domperidone; Female; Humans; Obsessive-C

2022
Kappa-opioid receptor stimulation quickens pathogenesis of compulsive checking in the quinpirole sensitization model of obsessive-compulsive disorder (OCD).
    Behavioral neuroscience, 2007, Volume: 121, Issue:5

    Topics: Algorithms; Animals; Benzazepines; Benzeneacetamides; Domperidone; Dopamine Agonists; Dopamine Antag

2007