domperidone has been researched along with Obesity in 2 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to investigate dopaminergic activity in two types of human obesity, childhood- and adult-onset, we have studied the responses of plasma TSH and prolactin to domperidone, a dopamine receptor antagonist, in 12 patients obese since early childhood, 12 patients with adult-onset obesity, and in 12 lean controls." | 3.67 | Evidence for differing dopaminergic activity in childhood- or adult-onset obesity. ( Baldini, M; Cantalamessa, L; Catania, A; Orsatti, A; Venegoni, E; Zanussi, C, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakano, H | 1 |
| Lee, SD | 1 |
| Farkas, GA | 1 |
| Catania, A | 1 |
| Cantalamessa, L | 1 |
| Venegoni, E | 1 |
| Orsatti, A | 1 |
| Baldini, M | 1 |
| Zanussi, C | 1 |
2 other studies available for domperidone and Obesity
| Article | Year |
|---|---|
Dopaminergic modulation of ventilation in obese Zucker rats.
Topics: Animals; Body Temperature; Domperidone; Dopamine; Dopamine Antagonists; Haloperidol; Hypercapnia; Hy | 2002 |
Evidence for differing dopaminergic activity in childhood- or adult-onset obesity.
Topics: Adolescent; Adult; Age Factors; Domperidone; Dopamine; Estradiol; Female; Humans; Middle Aged; Obesi | 1985 |