domperidone has been researched along with Neoplasms in 19 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We designed a comparative controlled study of Sulpiride and Domperidone, against nausea and vomiting during cancer chemotherapy." | 7.67 | [Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986) |
| "Severe cardiac arrhythmias occurred in two patients." | 5.27 | Cardiac arrhythmias during cytotoxic chemotherapy: role of domperidone. ( Hamer, J; Hunter, RW; Osborne, RJ; Slevin, ML, 1985) |
| "To compare ondansetron and domperidone for treatment of delayed nausea/vomiting (DN/V) following highly emetogenic chemotherapy, after attaining total suppression of emesis on the day of chemotherapy by mean of ondansetron (combined with dexamethasone in the case of cisplatin-treated patients)." | 5.08 | Prophylaxis of delayed nausea and vomiting after cancer chemotherapy. ( Borm, JJ; Esseboom, EU; Rojer, RA; Statius van Eps, LW, 1995) |
| " We designed a comparative controlled study of Sulpiride and Domperidone, against nausea and vomiting during cancer chemotherapy." | 3.67 | [Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986) |
| "A dose-finding multicenter study was undertaken to evaluate the antiemetic efficacy of domperidone, an antidopaminergic drug, which has been proposed as a suitable alternative to high-dose metoclopramide in the control of cisplatin-induced nausea and vomiting." | 3.67 | A pilot study of high-dose domperidone as an antiemetic in patients treated with cisplatin. ( del Favero, A; Franzosi, MG; Pampallona, S; Roila, F; Tognoni, G; Tonato, M, 1985) |
| "The antiemetic effect of domperidone against nausea, vomiting, and anorexia induced by antineoplastic agents was compared with that of chlorpromazine." | 3.66 | [Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine]. ( Araki, Y; Seita, M; Tamura, K, 1983) |
| "Domperidone was given twice a day for one week." | 1.27 | [Effect of combined use of adrenocortical hormones and domperidone as anti-emetics during cisplatin therapy]. ( Hirose, Y; Matsushita, T; Mise, K; Nakanishi, M; Shirosaki, H; Tanaka, T; Yamaoto, T, 1985) |
| "Severe cardiac arrhythmias occurred in two patients." | 1.27 | Cardiac arrhythmias during cytotoxic chemotherapy: role of domperidone. ( Hamer, J; Hunter, RW; Osborne, RJ; Slevin, ML, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Aoyama, M | 1 |
| Ishikawa, K | 1 |
| Nemoto, S | 1 |
| Hirano, H | 1 |
| Watanabe, N | 1 |
| Osada, H | 1 |
| Watanabe, S | 1 |
| Semba, K | 1 |
| De Bandt, D | 1 |
| Safsaf, S | 1 |
| Bourrion, B | 1 |
| Francois, M | 1 |
| Kamath, A | 1 |
| Rai, KM | 1 |
| Shreyas, R | 1 |
| Saxena, PUP | 1 |
| Banerjee, S | 1 |
| Tsukuura, H | 1 |
| Ando, Y | 1 |
| Gyawali, B | 1 |
| Matsumoto, M | 1 |
| Sugishita, M | 1 |
| Honda, K | 1 |
| Urakawa, H | 1 |
| Maeda, O | 1 |
| Hasegawa, Y | 1 |
| Smith, LA | 1 |
| Azariah, F | 1 |
| Lavender, VT | 1 |
| Stoner, NS | 1 |
| Bettiol, S | 1 |
| Usui, N | 1 |
| Ogawa, K | 1 |
| Inagaki, J | 1 |
| Horikoshi, N | 1 |
| Inoue, T | 1 |
| Murakami, M | 2 |
| Araki, Y | 1 |
| Tamura, K | 1 |
| Seita, M | 1 |
| Warde, P | 1 |
| Cantwell, B | 1 |
| Fennelly, J | 1 |
| Powderly, W | 1 |
| Conroy, R | 1 |
| Ise, T | 1 |
| Ohira, M | 1 |
| Omiya, A | 1 |
| Hirose, M | 1 |
| Shibata, T | 1 |
| Esseboom, EU | 1 |
| Rojer, RA | 1 |
| Borm, JJ | 1 |
| Statius van Eps, LW | 1 |
| Ota, K | 1 |
| Sakata, Y | 1 |
| Suzuki, H | 1 |
| Satoh, T | 1 |
| Kawatsu, S | 1 |
| Tanabe, K | 1 |
| Okamoto, K | 1 |
| Takagi, S | 1 |
| Komatsu, Y | 1 |
| Kawakami, K | 1 |
| Yoshida, Y | 1 |
| Shinkai, T | 1 |
| Saijo, N | 1 |
| Sawamura, N | 1 |
| Funaki, U | 1 |
| Takahashi, S | 1 |
| Yokoyama, S | 1 |
| Fujita, J | 1 |
| Futami, H | 1 |
| Sasaki, Y | 1 |
| Shimizu, E | 1 |
| Tanaka, T | 1 |
| Nakanishi, M | 1 |
| Hirose, Y | 1 |
| Mise, K | 1 |
| Matsushita, T | 1 |
| Yamaoto, T | 1 |
| Shirosaki, H | 1 |
| Tonato, M | 1 |
| Roila, F | 1 |
| del Favero, A | 1 |
| Tognoni, G | 1 |
| Franzosi, MG | 1 |
| Pampallona, S | 1 |
| Osborne, RJ | 1 |
| Slevin, ML | 1 |
| Hunter, RW | 1 |
| Hamer, J | 1 |
4 reviews available for domperidone and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy.
Topics: Adult; Antiemetics; Antineoplastic Agents; Cannabinoids; Chlorpromazine; Dizziness; Domperidone; Eup | 2015 |
[Recent advances in the management of chemotherapy-induced emesis].
Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Domperidone; Dronabinol; Drug Therapy, | 1986 |
[The control of chemotherapy-induced nausea and vomiting].
Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Chlorpromazine; Cisplatin; Domperidone; Hum | 1985 |
2 trials available for domperidone and Neoplasms
| Article | Year |
|---|---|
[Clinical evaluation of antiemetics for vomiting due to cancer chemotherapy in children].
Topics: Adolescent; Antiemetics; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; D | 1982 |
Prophylaxis of delayed nausea and vomiting after cancer chemotherapy.
Topics: Adult; Aged; Chi-Square Distribution; Cisplatin; Domperidone; Double-Blind Method; Female; Humans; M | 1995 |
13 other studies available for domperidone and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Lonidamine and domperidone inhibit expansion of transformed cell areas by modulating motility of surrounding nontransformed cells.
Topics: Animals; Antineoplastic Agents; Domperidone; Drug Screening Assays, Antitumor; Epithelial Cells; Ind | 2022 |
The evolution of anti-emetic prescriptions in primary care, between 2006 and 2016.
Topics: Antiemetics; Domperidone; Drug Prescriptions; Humans; Neoplasms; Prescriptions; Primary Health Care | 2021 |
Effect of domperidone, ondansetron, olanzapine-containing antiemetic regimen on QT
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Domperidone; Drug Co | 2021 |
Prophylactic Use of Antiemetics for Prevention of Opioid-Induced Nausea and Vomiting: A Questionnaire Survey among Japanese Physicians.
Topics: Analgesics, Opioid; Antiemetics; Benzodiazepines; Chemoprevention; Domperidone; Health Care Surveys; | 2015 |
[Domperidone suppositories treatment for nausea and vomiting during cancer chemotherapy].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Domperidone; Female; Humans; Male; Middle Aged; Naus | 1984 |
[Gastrointestinal disturbance by cancer chemotherapy--recent progress in antiemetic regimens].
Topics: Adult; Aged; Animals; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Domper | 1984 |
[Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine].
Topics: Adult; Aged; Antineoplastic Agents; Chlorpromazine; Domperidone; Female; Humans; Male; Middle Aged; | 1983 |
Alleviation of chemotherapy induced emesis by oral lorazepam and domperidone.
Topics: Adult; Antineoplastic Agents; Domperidone; Drug Therapy, Combination; Female; Humans; Lorazepam; Mal | 1983 |
[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Drug Evaluation; Female; H | 1986 |
[Effect of combined use of adrenocortical hormones and domperidone as anti-emetics during cisplatin therapy].
Topics: Adult; Aged; Breast Neoplasms; Cisplatin; Domperidone; Drug Therapy, Combination; Esophageal Neoplas | 1985 |
A pilot study of high-dose domperidone as an antiemetic in patients treated with cisplatin.
Topics: Adolescent; Adult; Aged; Cisplatin; Domperidone; Female; Humans; Infusions, Parenteral; Male; Middle | 1985 |
Cardiac arrhythmias during cytotoxic chemotherapy: role of domperidone.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Cisplat | 1985 |