Page last updated: 2024-10-26

domperidone and Nausea

domperidone has been researched along with Nausea in 93 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"In this randomized, double-blind, phase 3 study, children ages 6 months to 12 years with acute gastroenteritis randomly (1:1) received oral domperidone 0."9.30Safety and Efficacy of Low-dose Domperidone for Treating Nausea and Vomiting Due to Acute Gastroenteritis in Children. ( Appiani, C; Garces-Sanchez, M; Gupta, R; Hu, P; Leitz, G; Li, Q; Mitha, E, 2019)
"We investigated the usefulness of concurrent therapy of granisetron with methylprednisolone sodium for on nausea, vomiting and anorexia induced by chemotherapy, including cisplatin, in patients with oral cancer."9.07[Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin]. ( Kawashima, T; Miyata, K; Morita, N; Ohmata, T; Sakamoto, T; Wada, T, 1993)
" CMF were included in a double-blind comparative study aimed at evaluating the efficacy of 3 different drugs (methylprednisolone (MP), metoclopramide (MTC), and domperidone (DMP) in preventing chemotherapy-induced nausea and vomiting."9.06Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF. ( Ballatori, E; Basurto, C; del Favero, A; Minotti, V; Roila, F; Tonato, M, 1987)
"A randomized double-blind cross-over study was performed to evaluate the possible anti-emetic effect of the partial opiate antagonist buprenorphine in comparison to domperidone in chemotherapy-induced nausea and vomiting."9.06Buprenorphine versus domperidone in chemotherapy-induced emesis: a pilot study. ( Dullemond-Westland, AC; Neijt, JP; Nortier, JW; Sitsen, JM, 1986)
"In a single-blind trial of therapy in 20 patients with idiopathic Parkinson disease, domperidone prevented nausea and vomiting induced by bromocriptine without diminishing beneficial central effects."9.05Bromocriptine and domperidone in the treatment of Parkinson disease. ( Agid, Y; Illas, A; Lhermitte, F; Quinn, N, 1981)
"Domperidone improves symptoms of gastroparesis, reducing overall gastroparesis symptom severity and decreasing early satiety, postprandial fullness, and nausea."7.88Therapeutic response to domperidone in gastroparesis: A prospective study using the GCSI-daily diary. ( Heckert, J; Parkman, HP, 2018)
"There is increased awareness about risks and benefits of using domperidone to treat gastroparesis."7.83Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016)
"This retrospective audit demonstrates that domperidone is safe in the treatment of nausea associated with inpatient DHE infusion and headache."7.83Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache. ( Goadsby, PJ; Ito, H; Robbins, NM; Scheinman, MM, 2016)
"A retrospective chart review was conducted of patients with nausea (N) and vomiting (V) receiving domperidone from 2009 to 2013 under an Investigational New Drug (IND) protocol."7.81Cardiovascular safety profile and clinical experience with high-dose domperidone therapy for nausea and vomiting. ( Alvarez, A; Cooper, CJ; Gomez, Y; McCallum, RW; Ortiz, A; Sarosiek, I, 2015)
"To retrospectively analyze the individual risk factors for radioactive iodine (RAI)-associated nausea and vomiting, and to examine the anti-emetic effect of ramosetron (5-hydroxytryptamine-3 receptor antagonist) in RAI therapy."7.80Moderate to severe nausea in radioactive iodine (RAI) therapy is associated with the RAI dose per body weight and was not prevented by ramosetron. ( Ando, T; Ikeoka, T; Imaizumi, M; Kawakami, A; Ueki, I; Usa, T, 2014)
"Our aim was to determine whether domperidone could improve the symptoms of patients with gastroparesis, accelerate gastric emptying, and enhance quality of life."7.69The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis. ( McCallum, RW; Sarosiek, I; Soykan, I, 1997)
"Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone."7.68The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting. ( Lencz, L, 1990)
"Sulpiride, which has been utilized as an antipeptic ulcer and antidepressant in Japan, is one of the dopamine antagonists, and is considered to have anti vomiting activity."7.67[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986)
"At the end of the treatment period, nausea, vomiting and reflux symptoms, adverse events and a global assessment of patients' symptom control were recorded by the investigator."6.67A comparison of controlled release metoclopramide and domperidone in the treatment of nausea and vomiting. ( Miller, AJ; Patel, NH; Roy, P, 1991)
"Droperidol was significantly more effective than domperidone, metoclopramide or placebo in reducing emetic sequelae."6.66Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery. ( Madej, TH; Simpson, KH, 1986)
" High-dose metoclopramide has demonstrated efficacy in small series of patients in the treatment of cisplatin-induced vomiting."6.15Advances in anti-emetic therapy. ( Bakowski, MT, 1984)
"In this randomized, double-blind, phase 3 study, children ages 6 months to 12 years with acute gastroenteritis randomly (1:1) received oral domperidone 0."5.30Safety and Efficacy of Low-dose Domperidone for Treating Nausea and Vomiting Due to Acute Gastroenteritis in Children. ( Appiani, C; Garces-Sanchez, M; Gupta, R; Hu, P; Leitz, G; Li, Q; Mitha, E, 2019)
" The aim of this study was to compare the effectiveness and tolerability of a fixed combination of domperidone and paracetamol (Domperamol; Servier), which has anti-nauseant and anti-emetic activity, with sumatriptan 50 mg in moderate to severe migraine."5.09Comparison of a fixed combination of domperidone and paracetamol (Domperamol) with sumatriptan 50 mg in moderate to severe migraine: a randomised UK primary care study. ( Ball, K; Dowson, A; Haworth, D, 2000)
" During 5 days prior to the apomorphine all received Motilium (domperidone, 60 mg/d) to prevent nausea and vomiting."5.09[Apomorphine for treatment of "off-periods" in Parkinson's disease]. ( Kuritzky, A; Melamed, E; Merims, D; Ziv, I; Zoldan, J, 1999)
"Both drugs are effective, but domperidone (3 x 20 mg) is more effective than ondansetron (3 x 8 mg) for the prevention of the delayed nausea and/or vomiting which occur after highly emetogenic chemotherapy (p < 0."5.08Prophylaxis of delayed nausea and vomiting after cancer chemotherapy. ( Borm, JJ; Esseboom, EU; Rojer, RA; Statius van Eps, LW, 1995)
"We investigated the usefulness of concurrent therapy of granisetron with methylprednisolone sodium for on nausea, vomiting and anorexia induced by chemotherapy, including cisplatin, in patients with oral cancer."5.07[Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin]. ( Kawashima, T; Miyata, K; Morita, N; Ohmata, T; Sakamoto, T; Wada, T, 1993)
"A randomized double-blind cross-over study was performed to evaluate the possible anti-emetic effect of the partial opiate antagonist buprenorphine in comparison to domperidone in chemotherapy-induced nausea and vomiting."5.06Buprenorphine versus domperidone in chemotherapy-induced emesis: a pilot study. ( Dullemond-Westland, AC; Neijt, JP; Nortier, JW; Sitsen, JM, 1986)
" CMF were included in a double-blind comparative study aimed at evaluating the efficacy of 3 different drugs (methylprednisolone (MP), metoclopramide (MTC), and domperidone (DMP) in preventing chemotherapy-induced nausea and vomiting."5.06Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF. ( Ballatori, E; Basurto, C; del Favero, A; Minotti, V; Roila, F; Tonato, M, 1987)
"Domperidone was evaluated as an antiemetic in the control of nausea and vomiting associated with the administration of cytotoxic chemotherapy for various malignancies in a paediatric population."5.05Domperidone as an antiemetic in paediatric oncology. ( Mott, MG; O'Meara, A, 1981)
"In a single-blind trial of therapy in 20 patients with idiopathic Parkinson disease, domperidone prevented nausea and vomiting induced by bromocriptine without diminishing beneficial central effects."5.05Bromocriptine and domperidone in the treatment of Parkinson disease. ( Agid, Y; Illas, A; Lhermitte, F; Quinn, N, 1981)
"To evaluate the risk of QT prolongation, ventricular arrhythmias and sudden cardiac death associated with the use of oral domperidone in adults without cancer."4.91[Cardiac adverse effects of domperidone in adult patients: a systematic review]. ( Avila, A; Caraballo, L; Marzi, M; Molina, G; Piskulic, L; Weitz, D, 2015)
"A search of two bibliographic databases, the European Medicines Agency (EMA) website, Micromedex, Lexicomp and reference texts was undertaken for domperidone related reports of QT prolongation, cardiac arrhythmias and/or SCD."4.91Domperidone safety: a mini-review of the science of QT prolongation and clinical implications of recent global regulatory recommendations. ( Buffery, PJ; Strother, RM, 2015)
"In patients with advanced cancer not being treated with chemotherapy or radiation therapy, metoclopramide can be used to reduce nausea and vomiting."4.88[Treatment of nausea and vomiting with prokinetics and neuroleptics in palliative care patients : a review]. ( Alt-Epping, B; Benze, G; Geyer, A; Nauck, F, 2012)
"Risk-minimization measures (RMM), including label revisions were implemented in Europe for domperidone because of evidence of increased incidence of cardiac arrhythmia and sudden cardiac death."3.91Awareness of, and Compliance with, Domperidone Revised Labeling After a Risk-Minimization Activity in Europe. ( Fife, D; Hu, P; Kaplan, S; Oliveria, SA; Phillips, S; Richarz, U; Waller, J, 2019)
"Domperidone is a dopamine antagonist used for the symptomatic management of nausea and vomiting."3.91Impact of Safety Warning on Domperidone Prescribing for Geriatric Patients in South Korea: Analysis of National Insurance Claim Data. ( Han, N; Oh, JM; Rhew, K, 2019)
"Domperidone improves symptoms of gastroparesis, reducing overall gastroparesis symptom severity and decreasing early satiety, postprandial fullness, and nausea."3.88Therapeutic response to domperidone in gastroparesis: A prospective study using the GCSI-daily diary. ( Heckert, J; Parkman, HP, 2018)
"Domperidone, a peripheral D2 dopamine receptor antagonist, has efficacy for treatment of nausea, dyspepsia, and gastroparesis."3.85Domperidone is Commonly Prescribed With QT-Interacting Drugs: Review of a Community-based Practice and a Postmarketing Adverse Drug Event Reporting Database. ( Alexoff, A; Ehrenpreis, ED; Roginsky, G; Smith, DG, 2017)
"There is increased awareness about risks and benefits of using domperidone to treat gastroparesis."3.83Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016)
"This retrospective audit demonstrates that domperidone is safe in the treatment of nausea associated with inpatient DHE infusion and headache."3.83Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache. ( Goadsby, PJ; Ito, H; Robbins, NM; Scheinman, MM, 2016)
"A retrospective chart review was conducted of patients with nausea (N) and vomiting (V) receiving domperidone from 2009 to 2013 under an Investigational New Drug (IND) protocol."3.81Cardiovascular safety profile and clinical experience with high-dose domperidone therapy for nausea and vomiting. ( Alvarez, A; Cooper, CJ; Gomez, Y; McCallum, RW; Ortiz, A; Sarosiek, I, 2015)
"To retrospectively analyze the individual risk factors for radioactive iodine (RAI)-associated nausea and vomiting, and to examine the anti-emetic effect of ramosetron (5-hydroxytryptamine-3 receptor antagonist) in RAI therapy."3.80Moderate to severe nausea in radioactive iodine (RAI) therapy is associated with the RAI dose per body weight and was not prevented by ramosetron. ( Ando, T; Ikeoka, T; Imaizumi, M; Kawakami, A; Ueki, I; Usa, T, 2014)
"Domperidone is a dopamine antagonist that has recently been released in Canada."3.76Domperidone, a new dopamine antagonist. ( Champion, MC; Hartnett, M; Yen, M, 1986)
"Our aim was to determine whether domperidone could improve the symptoms of patients with gastroparesis, accelerate gastric emptying, and enhance quality of life."3.69The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis. ( McCallum, RW; Sarosiek, I; Soykan, I, 1997)
"Antiemetic effect and safety of concurrent administration of ondansetron and other antiemetics (dexamethasone, domperidone and ethyl loflazepate), given for complete suppression of nausea/vomiting, were examined in 46 patients (109 courses) with gynecological cancer receiving single high-dose of cisplatin or carboplatin."3.69[Multi-drug antiemetic treatment and effect of treatment duration of concurrent steroids--for complete control of chemotherapy-induced nausea/vomiting in gynecological cancer]. ( Fujii, T; Kioka, H; Naito, H; Nakata, N; Sawasaki, T; Shigemasa, K; Shiroyama, Y; Tanimoto, H, 1997)
"Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone."3.68The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting. ( Lencz, L, 1990)
"The incidence of dyspepsias and emesis occurring either as accompanying symptoms of gynaecological operations or as independent clinical conditions, therapeutic means for controlling these conditions and the mechanism of action and clinical usefulness of the dopamine antagonist domperidone have been discussed."3.67Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting. ( Sásdi, A, 1989)
"A dose-finding multicenter study was undertaken to evaluate the antiemetic efficacy of domperidone, an antidopaminergic drug, which has been proposed as a suitable alternative to high-dose metoclopramide in the control of cisplatin-induced nausea and vomiting."3.67A pilot study of high-dose domperidone as an antiemetic in patients treated with cisplatin. ( del Favero, A; Franzosi, MG; Pampallona, S; Roila, F; Tognoni, G; Tonato, M, 1985)
"Sulpiride, which has been utilized as an antipeptic ulcer and antidepressant in Japan, is one of the dopamine antagonists, and is considered to have anti vomiting activity."3.67[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986)
"The administration of alfentanil by continuous infusion as supplementation to nitrous oxide for shortlasting anesthesias has been studied in 51 patients."3.66Continuous infusion of alfentanil. ( Booij, LH; Pelgrom, R; Steegers, PA, 1982)
"The antiemetic effect of domperidone against nausea, vomiting, and anorexia induced by antineoplastic agents was compared with that of chlorpromazine."3.66[Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine]. ( Araki, Y; Seita, M; Tamura, K, 1983)
"A recently developed oral serotonergic challenge test consisting of 5-Hydroxytryptophane (5-HTP, 200 mg) combined with carbidopa (CBD, 100 mg + 50 mg) exhibited dose-related neuroendocrine responsiveness and predictable pharmacokinetics."2.75Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron. ( de Kam, ML; Derijk, RH; Jacobs, GE; Kamerling, IM; van Gerven, JM; van Pelt, J; Zitman, FG, 2010)
"At the end of the treatment period, nausea, vomiting and reflux symptoms, adverse events and a global assessment of patients' symptom control were recorded by the investigator."2.67A comparison of controlled release metoclopramide and domperidone in the treatment of nausea and vomiting. ( Miller, AJ; Patel, NH; Roy, P, 1991)
"Droperidol was significantly more effective than domperidone, metoclopramide or placebo in reducing emetic sequelae."2.66Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery. ( Madej, TH; Simpson, KH, 1986)
"Nausea and vomiting are reported in approximately 60% of neoplastic patients treated with doxorubicin used alone at doses greater than or equal to 50 mg/m2 or in combination with other noncisplatin antiblastic agents."2.66A double-blind trial comparing antiemetic efficacy and toxicity of metoclopramide versus methylprednisolone versus domperidone in patients receiving doxorubicin chemotherapy alone or in combination with other antiblastic agents. ( Ballatori, E; Basurto, C; Bracarda, S; Del Favero, A; Roila, F; Tonato, M, 1988)
" It thus provides an excellent safety profile for long-term administration orally in the recommended doses."2.44Domperidone: review of pharmacology and clinical applications in gastroenterology. ( McCallum, RW; Reddymasu, SC; Soykan, I, 2007)
"Functional vomiting is rare and presents with more frequent vomiting episodes."2.44Functional nausea and vomiting. ( Talley, NJ, 2007)
"Nausea and vomiting are common symptoms of migraine, which can be controlled with a variety of anti-emetics including phenothiazines and antihistamines."2.41Anti-emetics. ( MacGregor, EA, 2001)
"Apomorphine is a potent short-acting D1/D2 dopamine agonist administered sub-cutaneously that is used in the treatment of PD."1.35The pragmatic use of apomorphine at the end of life. ( Dewhurst, F; Lee, M; Wood, B, 2009)
" If nicotinamide was given in combination with domperidone, 86% of the patients continued the nicotinamide medication until the end of the treatment period."1.31Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy. ( Bussink, J; Folkes, LK; Kaanders, JH; Stratford, MR; van der Kogel, AJ, 2002)
"Patients with migraine show a hypersensitivity to dopamine or its agonists."1.27Pharmacological exploration of dopamine hypersensitivity in migraine patients. ( Bès, A; Bessoles, G; Dupui, P; Géraud, G; Güell, A, 1986)
"Domperidone was given twice a day for one week."1.27[Effect of combined use of adrenocortical hormones and domperidone as anti-emetics during cisplatin therapy]. ( Hirose, Y; Matsushita, T; Mise, K; Nakanishi, M; Shirosaki, H; Tanaka, T; Yamaoto, T, 1985)

Research

Studies (93)

TimeframeStudies, this research(%)All Research%
pre-199047 (50.54)18.7374
1990's12 (12.90)18.2507
2000's10 (10.75)29.6817
2010's22 (23.66)24.3611
2020's2 (2.15)2.80

Authors

AuthorsStudies
Monković, I1
Willner, D1
Adam, MA1
Brown, M1
Crenshaw, RR1
Fuller, CE1
Juby, PF1
Luke, GM1
Matiskella, JA1
Montzka, TA1
Rhew, K1
Han, N1
Oh, JM1
Kamath, A1
Rai, KM1
Shreyas, R1
Saxena, PUP1
Banerjee, S1
Yan, XJ1
Xu, P1
Qiu, HY1
Wang, B1
Luo, QQ1
Chen, SL1
Braillon, A1
Robbins, NM2
Goadsby, PJ2
Heckert, J1
Parkman, HP2
Giusti, R1
Mazzotta, M1
Filetti, M1
Daniele, G1
Tsukuura, H2
Ficorella, C1
Porzio, G1
Marchetti, P1
Verna, L1
Leitz, G1
Hu, P2
Appiani, C1
Li, Q1
Mitha, E1
Garces-Sanchez, M1
Gupta, R1
Di Lorenzo, C1
Nurko, S1
Fife, D1
Waller, J1
Kaplan, S1
Phillips, S1
Oliveria, SA1
Richarz, U1
Ikeoka, T1
Ando, T1
Imaizumi, M1
Ueki, I1
Usa, T1
Kawakami, A1
Ramos, L1
Alarcón, O1
Adrian, Z1
Gimeno-García, AZ1
Nicolás-Pérez, D1
Jiménez-Sosa, A1
Quintero, E1
Furyk, JS1
Meek, R1
McKenzie, S1
Shailendra, B1
Shailendra, M1
Manish, J1
Singh, TY1
Priti, T1
Ortiz, A1
Cooper, CJ1
Alvarez, A1
Gomez, Y1
Sarosiek, I2
McCallum, RW3
Marzi, M1
Weitz, D1
Avila, A1
Molina, G1
Caraballo, L1
Piskulic, L1
Buffery, PJ1
Strother, RM1
Ando, Y1
Gyawali, B1
Matsumoto, M1
Sugishita, M1
Honda, K1
Urakawa, H1
Maeda, O1
Hasegawa, Y1
Smith, LA1
Azariah, F1
Lavender, VT1
Stoner, NS1
Bettiol, S1
Ehrenpreis, ED1
Roginsky, G1
Alexoff, A1
Smith, DG1
Schey, R1
Saadi, M1
Midani, D1
Roberts, AC1
Parupalli, R1
Ito, H1
Scheinman, MM1
Jacobs, GE1
Kamerling, IM1
de Kam, ML1
Derijk, RH1
van Pelt, J1
Zitman, FG1
van Gerven, JM1
Dewhurst, F1
Lee, M1
Wood, B1
Festin, M1
Benze, G1
Alt-Epping, B1
Geyer, A1
Nauck, F1
Bussink, J1
Stratford, MR1
van der Kogel, AJ1
Folkes, LK1
Kaanders, JH1
MacGregor, EA1
Reddymasu, SC1
Soykan, I2
Talley, NJ1
Robinson, P1
Bakowski, MT1
Guldager, H1
Jensen, FM1
Andersen, KH1
Arnfred, I1
Clarke, RS1
Spelina, KR1
Gerber, HR1
Pagels, IL1
Valenzuela, JE1
Dooley, CP1
Roussak, JB1
Carey, P1
Parry, H1
Usui, N1
Ogawa, K1
Inagaki, J1
Horikoshi, N1
Inoue, T1
Murakami, M2
Urabe, A1
Saito, T1
Takaku, F1
Araki, Y1
Tamura, K1
Seita, M1
Steegers, PA1
Booij, LH1
Pelgrom, R1
Caruso, U1
D'Iddio, S1
Cravotto, E1
Pesce, S1
Betti, I1
Ruscitto, G1
Ecari, U1
Sabrie, AM1
O'Meara, A1
Mott, MG1
Minobe, T1
Sekine, H1
Torii, T1
Fujiya, T1
Ohtomo, Y1
Bogaert, M1
Quinn, N1
Illas, A1
Lhermitte, F1
Agid, Y1
Esseboom, EU1
Rojer, RA1
Borm, JJ1
Statius van Eps, LW1
Kawashima, T1
Wada, T1
Morita, N1
Ohmata, T1
Miyata, K1
Sakamoto, T1
Rampello, L1
Raffaele, R1
Nicoletti, G1
Le Pira, F1
Vecchio, I1
Malaguarnera, M1
Drago, F1
Fujii, T1
Nakata, N1
Shiroyama, Y1
Sawasaki, T1
Tanimoto, H1
Shigemasa, K1
Kioka, H1
Naito, H1
Zoldan, J1
Merims, D1
Kuritzky, A1
Ziv, I1
Melamed, E1
Dowson, A1
Ball, K1
Haworth, D1
Franchi, F1
Lazzeri, C1
Barletta, G1
Ianni, L1
Mannelli, M1
Polubiec, A1
Krasnopolska-Polanczky, Z1
Duda-Król, W1
Jórasz, I1
Witkowski, J1
Varga, A1
Lovas, J1
Roy, P1
Patel, NH1
Miller, AJ1
Bonuccelli, U1
Nocchiero, A1
Napolitano, A1
Paoletti, AM1
Melis, GB1
Corsini, GU1
Muratorio, A1
Lencz, L1
Williams, CJ1
Davies, C1
Raval, M1
Middleton, J1
Luken, J1
Stone, B1
Sásdi, A1
Cherian, S1
Sachdev, HP1
Puri, RK1
Dodds, LJ1
Madej, TH2
Simpson, KH2
Ota, K1
Dalzell, AM1
Bartlett, H1
Lilleyman, JS1
Champion, MC2
Cunningham, D1
Evans, C1
Gazet, JC1
Ford, H1
Pople, A1
Dearling, J1
Chappell, D1
Coombes, C1
Basurto, C2
Roila, F3
Bracarda, S1
Tonato, M3
Ballatori, E2
Del Favero, A3
Fister, T1
Wilson, S1
Takács, G1
Udvardi, G1
Minotti, V1
Kis Csitári, I1
Dullemond-Westland, AC1
Neijt, JP1
Nortier, JW1
Sitsen, JM1
Hartnett, M1
Yen, M1
Nappi, C1
Colace, G1
Di Renzo, GF1
Taglialatela, M1
Amoroso, S1
Annunziato, L1
Montemagno, U1
Sakata, Y1
Suzuki, H1
Satoh, T1
Kawatsu, S1
Tanabe, K1
Okamoto, K1
Takagi, S1
Komatsu, Y1
Kawakami, K1
Yoshida, Y1
Bès, A1
Dupui, P1
Güell, A1
Bessoles, G1
Géraud, G1
Waldmann, CS1
Verghese, C1
Short, SM1
Goldhill, DR1
Evans, SJ1
Huys, J1
Troch, M1
Bourguignon, RP1
Smets, P1
Shinkai, T1
Saijo, N1
Sawamura, N1
Funaki, U1
Takahashi, S1
Yokoyama, S1
Fujita, J1
Futami, H1
Sasaki, Y1
Shimizu, E1
Cameron, HA1
Reyntjens, AJ1
Lake-Bakaar, G1
Leeser, J1
Bateman, DN1
Tanaka, T1
Nakanishi, M1
Hirose, Y1
Mise, K1
Matsushita, T1
Yamaoto, T1
Shirosaki, H1
Tognoni, G1
Franzosi, MG1
Pampallona, S1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group, Prospective Study to Evaluate the Safety and Efficacy of Domperidone in 6-month-old to 12-year-old Pediatric Subjects With Nausea and Vomiting Due to Acute Gastroenteritis[NCT02699385]Phase 310 participants (Actual)Interventional2015-12-07Terminated (stopped due to Study prematurely terminated upon recommendation of IDMC due to lack of efficacy.)
An Investigational New Drug Program for the Use of Domperidone in the Treatment of Refractory Gastroesophageal Reflux Disease and Other Gastrointestinal Motility Disorders[NCT00777439]75 participants (Anticipated)Interventional2008-10-31Recruiting
Oral Domperidone for Relief of Gastrointestinal Disorders in Patients Who Failed Standard Therapy[NCT00761254]42 participants (Actual)Interventional2008-08-31Terminated (stopped due to PI withdrew due to increased responsibilities in clinical department.)
Does Domperidone, a D2-antagonist Alter Gastric Emptying Rates and Appetite Sensations in Healthy Adults?[NCT01347814]13 participants (Actual)Interventional2008-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

18 reviews available for domperidone and Nausea

ArticleYear
[Cardiac adverse effects of domperidone in adult patients: a systematic review].
    Revista medica de Chile, 2015, Volume: 143, Issue:1

    Topics: Adult; Antiemetics; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Domperidone; Female; Gastroesophag

2015
Domperidone safety: a mini-review of the science of QT prolongation and clinical implications of recent global regulatory recommendations.
    The New Zealand medical journal, 2015, Jun-12, Volume: 128, Issue:1416

    Topics: Antiemetics; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Death, Sudde

2015
Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy.
    The Cochrane database of systematic reviews, 2015, Nov-12, Issue:11

    Topics: Adult; Antiemetics; Antineoplastic Agents; Cannabinoids; Chlorpromazine; Dizziness; Domperidone; Eup

2015
Nausea and vomiting in early pregnancy.
    BMJ clinical evidence, 2009, Jun-03, Volume: 2009

    Topics: Acupressure; Administration, Oral; Domperidone; Female; Humans; Metoclopramide; Nausea; Phytotherapy

2009
[Treatment of nausea and vomiting with prokinetics and neuroleptics in palliative care patients : a review].
    Schmerz (Berlin, Germany), 2012, Volume: 26, Issue:5

    Topics: Antiemetics; Antipsychotic Agents; Chronic Disease; Domperidone; Dopamine Antagonists; Drug Therapy,

2012
Anti-emetics.
    Current medical research and opinion, 2001, Volume: 17 Suppl 1

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Humans; Metoclopramide; Migraine Disorders; Nausea;

2001
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Domperidone: review of pharmacology and clinical applications in gastroenterology.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:9

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting

2007
Functional nausea and vomiting.
    Australian family physician, 2007, Volume: 36, Issue:9

    Topics: Acute Disease; Antidepressive Agents, Tricyclic; Antiemetics; Chronic Disease; Diagnosis, Differenti

2007
Advances in anti-emetic therapy.
    Cancer treatment reviews, 1984, Volume: 11, Issue:3

    Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Clinical Trials as Topic; Dexamethasone; Do

1984
Nausea and vomiting.
    British journal of anaesthesia, 1984, Volume: 56, Issue:1

    Topics: Analgesics; Anesthetics; Domperidone; Humans; Metoclopramide; Nausea; Phenothiazines; Piperazines; S

1984
Dopamine antagonists in the upper gastrointestinal tract.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 96

    Topics: Diabetic Neuropathies; Digestive System; Domperidone; Dopamine Antagonists; Duodenum; Dyspepsia; Eso

1984
Domperidone-induced acute dystonia and polycystic ovary syndrome.
    Movement disorders : official journal of the Movement Disorder Society, 1991, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Domperidone; Dyskinesia, Drug-Induced; Dystonia; Estrogens; Female; Humans; Nause

1991
Domperidone.
    Indian pediatrics, 1989, Volume: 26, Issue:9

    Topics: Child; Child, Preschool; Domperidone; Gastric Emptying; Humans; Nausea; Vomiting

1989
The control of cancer chemotherapy-induced nausea and vomiting.
    Journal of clinical and hospital pharmacy, 1985, Volume: 10, Issue:2

    Topics: Adrenal Cortex Hormones; Anti-Anxiety Agents; Antiemetics; Antineoplastic Agents; Antipsychotic Agen

1985
[Recent advances in the management of chemotherapy-induced emesis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1

    Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Domperidone; Dronabinol; Drug Therapy,

1986
Domperidone.
    General pharmacology, 1988, Volume: 19, Issue:4

    Topics: Colonic Diseases, Functional; Domperidone; Dyspepsia; Esophagitis, Peptic; Gastrointestinal Motility

1988
Domperidone, a new dopamine antagonist.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1986, Sep-01, Volume: 135, Issue:5

    Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; Dys

1986
[The control of chemotherapy-induced nausea and vomiting].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:7

    Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Chlorpromazine; Cisplatin; Domperidone; Hum

1985

Trials

31 trials available for domperidone and Nausea

ArticleYear
Antiemetics improve the tolerance of polyethylene glycol for colonoscopy preparation: A randomized clinical trial.
    Medicine, 2021, Mar-12, Volume: 100, Issue:10

    Topics: Adult; Aged; Antiemetics; Cathartics; Colon; Colonoscopy; Domperidone; Female; Humans; Incidence; In

2021
Safety and Efficacy of Low-dose Domperidone for Treating Nausea and Vomiting Due to Acute Gastroenteritis in Children.
    Journal of pediatric gastroenterology and nutrition, 2019, Volume: 69, Issue:4

    Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Domperidone; Double-Blind

2019
One-day versus two-day cleansing for colon capsule endoscopy: a prospective randomized pilot study.
    Gastroenterologia y hepatologia, 2014, Volume: 37, Issue:3

    Topics: Abdominal Pain; Adult; Aged; Bisacodyl; Capsule Endoscopy; Cathartics; Colon; Dietary Fiber; Domperi

2014
Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Antidepressive Agents, Second-Generation; Antiemetics; Area

2010
Advances in anti-emetic therapy.
    Cancer treatment reviews, 1984, Volume: 11, Issue:3

    Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Clinical Trials as Topic; Dexamethasone; Do

1984
[Domperidone and metoclopramide in the prevention of postoperative nausea and vomiting].
    Ugeskrift for laeger, 1983, Jun-06, Volume: 145, Issue:23

    Topics: Abortion, Induced; Adolescent; Adult; Clinical Trials as Topic; Domperidone; Double-Blind Method; Fe

1983
Nausea and vomiting during spinal anaesthesia. Effect of metoclopramide and domperidone: a double-blind trial.
    Anaesthesia, 1984, Volume: 39, Issue:2

    Topics: Aged; Anesthesia, Spinal; Blood Pressure; Clinical Trials as Topic; Domperidone; Double-Blind Method

1984
[Domperidone as an anti-emetic in antineoplastic chemotherapy].
    Minerva chirurgica, 1981, Jun-15, Volume: 36, Issue:11

    Topics: Aged; Antineoplastic Agents; Benzimidazoles; Clinical Trials as Topic; Domperidone; Female; Gastroin

1981
Domperidone as an antiemetic in paediatric oncology.
    Cancer chemotherapy and pharmacology, 1981, Volume: 6, Issue:2

    Topics: Antiemetics; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; Domperidone;

1981
[The effect of domperidone in the prevention of nausea and vomiting during post-operative recovery period from anesthesia--a double blind study (author's transl)].
    Masui. The Japanese journal of anesthesiology, 1981, Volume: 30, Issue:12

    Topics: Adult; Anesthesia; Clinical Trials as Topic; Domperidone; Double-Blind Method; Female; Humans; Male;

1981
Bromocriptine and domperidone in the treatment of Parkinson disease.
    Neurology, 1981, Volume: 31, Issue:6

    Topics: Benzimidazoles; Bromocriptine; Domperidone; Female; Humans; Levodopa; Male; Middle Aged; Nausea; Par

1981
Prophylaxis of delayed nausea and vomiting after cancer chemotherapy.
    The Netherlands journal of medicine, 1995, Volume: 47, Issue:1

    Topics: Adult; Aged; Chi-Square Distribution; Cisplatin; Domperidone; Double-Blind Method; Female; Humans; M

1995
[Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:13

    Topics: Adult; Aged; Anorexia; Cisplatin; Domperidone; Drug Therapy, Combination; Female; Granisetron; Human

1993
Neurobehavioral syndrome induced by H2-receptor blocker withdrawal: possible role of prolactin.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:1

    Topics: Adult; Anorexia; Antiemetics; Cimetidine; Domperidone; Female; Histamine H2 Antagonists; Humans; Mal

1997
[Apomorphine for treatment of "off-periods" in Parkinson's disease].
    Harefuah, 1999, Nov-15, Volume: 137, Issue:10

    Topics: Aged; Antiparkinson Agents; Apomorphine; Domperidone; Female; Humans; Injections, Subcutaneous; Levo

1999
Comparison of a fixed combination of domperidone and paracetamol (Domperamol) with sumatriptan 50 mg in moderate to severe migraine: a randomised UK primary care study.
    Current medical research and opinion, 2000, Volume: 16, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cost-Benefit Analysis; Cross-Over Studies; Domperido

2000
Centrally mediated effects of bromocriptine on cardiac sympathovagal balance.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:1

    Topics: Adult; Aortic Bodies; Bromocriptine; Dizziness; Domperidone; Dopamine Agonists; Dopamine Antagonists

2001
Evaluation of the antiemetic effect of domperidon in patients treated with cytostatic drugs.
    Therapia Hungarica (English edition), 1992, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Female; Humans

1992
A comparison of controlled release metoclopramide and domperidone in the treatment of nausea and vomiting.
    The British journal of clinical practice, 1991,Winter, Volume: 45, Issue:4

    Topics: Delayed-Action Preparations; Domperidone; Double-Blind Method; Female; Humans; Male; Metoclopramide;

1991
Comparison of starting antiemetic treatment 24 hours before or concurrently with cytotoxic chemotherapy.
    BMJ (Clinical research ed.), 1989, Feb-18, Volume: 298, Issue:6671

    Topics: Administration, Oral; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials a

1989
Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery.
    British journal of anaesthesia, 1986, Volume: 58, Issue:8

    Topics: Abdomen; Adult; Antiemetics; Clinical Trials as Topic; Domperidone; Droperidol; Female; Humans; Hyst

1986
Nabilone: an alternative antiemetic for cancer chemotherapy.
    Archives of disease in childhood, 1986, Volume: 61, Issue:5

    Topics: Adolescent; Antiemetics; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; D

1986
Comparison of antiemetic efficacy of domperidone, metoclopramide, and dexamethasone in patients receiving outpatient chemotherapy regimens.
    British medical journal (Clinical research ed.), 1987, Jul-25, Volume: 295, Issue:6592

    Topics: Adult; Aged; Ambulatory Care; Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Dexameth

1987
A double-blind trial comparing antiemetic efficacy and toxicity of metoclopramide versus methylprednisolone versus domperidone in patients receiving doxorubicin chemotherapy alone or in combination with other antiblastic agents.
    American journal of clinical oncology, 1988, Volume: 11, Issue:5

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Double-Blind Method; Doxor

1988
Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:6

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as To

1987
Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following gynaecological surgery in day cases.
    British journal of anaesthesia, 1986, Volume: 58, Issue:8

    Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Antiemetics; Clinical Trials as Topic; Dila

1986
Buprenorphine versus domperidone in chemotherapy-induced emesis: a pilot study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1986, Volume: 6, Issue:2

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Buprenorphine; Clinical Trials as Topic; Domperidon

1986
Domperidone, a new dopamine antagonist.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1986, Sep-01, Volume: 135, Issue:5

    Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; Dys

1986
Domperidone antagonizes bromoergocriptine--induced nausea and vomiting without affecting its inhibition of prolactin secretion in puerperal women.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:5

    Topics: Adult; Bromocriptine; Domperidone; Drug Therapy, Combination; Female; Humans; Hyperprolactinemia; Na

1987
The evaluation of domperidone and metoclopramide as antiemetics in day care abortion patients.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:3

    Topics: Abortion, Therapeutic; Adolescent; Adult; Anesthesia, General; Anesthesia, Obstetrical; Clinical Tri

1985
High-dose alizapride versus high-dose domperidone: a double-blind comparative study in the management of cis-platinum-induced emesis.
    Current medical research and opinion, 1985, Volume: 9, Issue:6

    Topics: Antiemetics; Cisplatin; Clinical Trials as Topic; Domperidone; Double-Blind Method; Female; Humans;

1985

Other Studies

46 other studies available for domperidone and Nausea

ArticleYear
Substituted benzamides. 1. Potential nondopaminergic antagonists of chemotherapy-induced nausea and emesis.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:8

    Topics: Animals; Antiemetics; Benzamides; Catalepsy; Chemical Phenomena; Chemistry; Cisplatin; Dogs; Dopamin

1988
Impact of Safety Warning on Domperidone Prescribing for Geriatric Patients in South Korea: Analysis of National Insurance Claim Data.
    International journal of environmental research and public health, 2019, 08-20, Volume: 16, Issue:16

    Topics: Aged; Antiemetics; Domperidone; Electrocardiography; Female; Heart Diseases; Humans; Male; Nausea; P

2019
Effect of domperidone, ondansetron, olanzapine-containing antiemetic regimen on QT
    Scientific reports, 2021, 01-11, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Domperidone; Drug Co

2021
Letter re: Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache.
    Neurology, 2017, 05-30, Volume: 88, Issue:22

    Topics: Dihydroergotamine; Domperidone; Headache; Humans; Nausea

2017
Author response: Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache.
    Neurology, 2017, 05-30, Volume: 88, Issue:22

    Topics: Dihydroergotamine; Domperidone; Headache; Humans; Nausea

2017
Therapeutic response to domperidone in gastroparesis: A prospective study using the GCSI-daily diary.
    Neurogastroenterology and motility, 2018, Volume: 30, Issue:1

    Topics: Adult; Antiemetics; Diabetes Complications; Domperidone; Female; Gastric Emptying; Gastroparesis; Hu

2018
Prophylactic use of antiemetics for prevention of opioid-induced nausea and vomiting: a survey about Italian physicians' practice.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019, Volume: 27, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Analgesics, Opioid; Antiemetics; Antipsychotic Agents; Cross-Section

2019
It Is Ok to Be Negative!
    Journal of pediatric gastroenterology and nutrition, 2019, Volume: 69, Issue:4

    Topics: Child; Domperidone; Gastroenteritis; Humans; Nausea; Vomiting

2019
Awareness of, and Compliance with, Domperidone Revised Labeling After a Risk-Minimization Activity in Europe.
    Clinical drug investigation, 2019, Volume: 39, Issue:11

    Topics: Adult; Antiemetics; Arrhythmias, Cardiac; Cardiac Conduction System Disease; Cross-Sectional Studies

2019
Moderate to severe nausea in radioactive iodine (RAI) therapy is associated with the RAI dose per body weight and was not prevented by ramosetron.
    Endocrine, 2014, Volume: 46, Issue:1

    Topics: Adenoma; Adult; Aged; Antiemetics; Benzimidazoles; Domperidone; Dose-Response Relationship, Radiatio

2014
Drug treatment of adults with nausea and vomiting in primary care.
    BMJ (Clinical research ed.), 2014, Aug-07, Volume: 349

    Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopra

2014
Design and Optimization of Domperidone Fast Dissolving Tablet Using Central Composite Design.
    Current drug delivery, 2015, Volume: 12, Issue:6

    Topics: Animals; Antiemetics; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Citric Acid; Domperi

2015
Cardiovascular safety profile and clinical experience with high-dose domperidone therapy for nausea and vomiting.
    The American journal of the medical sciences, 2015, Volume: 349, Issue:5

    Topics: Adult; Cardiotoxicity; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Mon

2015
Prophylactic Use of Antiemetics for Prevention of Opioid-Induced Nausea and Vomiting: A Questionnaire Survey among Japanese Physicians.
    Journal of palliative medicine, 2015, Volume: 18, Issue:11

    Topics: Analgesics, Opioid; Antiemetics; Benzodiazepines; Chemoprevention; Domperidone; Health Care Surveys;

2015
Domperidone is Commonly Prescribed With QT-Interacting Drugs: Review of a Community-based Practice and a Postmarketing Adverse Drug Event Reporting Database.
    Journal of clinical gastroenterology, 2017, Volume: 51, Issue:1

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antiemetics; Domperidone; D

2017
Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:12

    Topics: Adult; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Diarrhea; Domperidone; Dopamine An

2016
Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache.
    Neurology, 2016, Dec-13, Volume: 87, Issue:24

    Topics: Adolescent; Adult; Aged; Antiemetics; Dihydroergotamine; Domperidone; Female; Headache; Humans; Male

2016
Domperidone and sudden death. Cardiac rhythm disorders: QT interval prolongation.
    Prescrire international, 2008, Volume: 17, Issue:94

    Topics: Antiemetics; Arrhythmias, Cardiac; Canada; Death, Sudden, Cardiac; Domperidone; Humans; Long QT Synd

2008
The pragmatic use of apomorphine at the end of life.
    Palliative medicine, 2009, Volume: 23, Issue:8

    Topics: Aged; Antiemetics; Antiparkinson Agents; Apomorphine; Blinking; Deglutition Disorders; Domperidone;

2009
Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2002, Volume: 63, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma; Domperidone; Dose Fractionation, Radiatio

2002
Dosage and drug interactions of domperidone.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:4

    Topics: Antiemetics; Domperidone; Dopamine Antagonists; Drug Interactions; Drug Labeling; Gastrointestinal D

2008
Cardiac arrest after treatment with intravenous domperidone.
    British medical journal (Clinical research ed.), 1984, Dec-08, Volume: 289, Issue:6458

    Topics: Adult; Domperidone; Female; Heart Arrest; Humans; Middle Aged; Nausea; Vomiting

1984
[Domperidone suppositories treatment for nausea and vomiting during cancer chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Domperidone; Female; Humans; Male; Middle Aged; Naus

1984
[Gastrointestinal disturbance by cancer chemotherapy--recent progress in antiemetic regimens].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:9 Suppl

    Topics: Adult; Aged; Animals; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Domper

1984
[Effects of domperidone suppository against adverse reactions in digestive organs induced by cancer chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 2

    Topics: Adult; Aged; Anorexia; Antineoplastic Agents; Domperidone; Female; Hodgkin Disease; Humans; Leukemia

1984
[Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents; Chlorpromazine; Domperidone; Female; Humans; Male; Middle Aged;

1983
Continuous infusion of alfentanil.
    Acta anaesthesiologica Belgica, 1982, Volume: 33, Issue:2

    Topics: Adult; Alfentanil; Anesthesia; Blood Pressure; Domperidone; Droperidol; Female; Fentanyl; Heart Rate

1982
[Nausea and vomiting: pharmacologic aspects].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1982, Volume: 44, Issue:3-4

    Topics: Animals; Antiemetics; Dogs; Domperidone; Humans; Nausea; Receptors, Dopamine; Vomiting

1982
The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:6

    Topics: Abdominal Pain; Administration, Oral; Adult; Aged; Antiemetics; Domperidone; Dopamine Antagonists; E

1997
[Multi-drug antiemetic treatment and effect of treatment duration of concurrent steroids--for complete control of chemotherapy-induced nausea/vomiting in gynecological cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:15

    Topics: Administration, Oral; Adult; Aged; Anti-Anxiety Agents; Antiemetics; Antineoplastic Combined Chemoth

1997
Radiation-induced emesis: a prospective observational multicenter Italian trial. The Italian Group for Antiemetic Research in Radiotherapy.
    International journal of radiation oncology, biology, physics, 1999, Jun-01, Volume: 44, Issue:3

    Topics: Adult; Antiemetics; Domperidone; Drug Administration Schedule; Female; Humans; Incidence; Indoles; M

1999
Some possible gynaecological indications for peripheral antidopamine therapy.
    Therapia Hungarica (English edition), 1992, Volume: 40, Issue:1

    Topics: Adult; Climacteric; Domperidone; Drug Evaluation; Dyspepsia; Female; Gastrointestinal Diseases; Huma

1992
The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting.
    Therapia Hungarica (English edition), 1990, Volume: 38, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Dimenhydrinate; Domperidone; Femal

1990
Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting.
    Therapia Hungarica (English edition), 1989, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Aged; Domperidone; Dyspepsia; Female; Genital Diseases, Female; Humans; Hyperemes

1989
Use of Motilium in the perioperative period from the aspect of the anaesthesiologist.
    Therapia Hungarica (English edition), 1988, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Domperidone; Female; Humans; Middle Aged; Nausea; Preanesthetic Medication; Vomit

1988
Domperidone: an alternative to metoclopramide.
    Drug and therapeutics bulletin, 1988, Jul-25, Volume: 26, Issue:15

    Topics: Acute Disease; Adolescent; Adult; Child; Domperidone; Humans; Metoclopramide; Nausea; Vomiting

1988
Domperidone.
    The Australian nurses' journal. Royal Australian Nursing Federation, 1988, Volume: 18, Issue:3

    Topics: Domperidone; Humans; Nausea; Vomiting

1988
Effect of domperidone on postoperative vomiting and dyspepsia aggravated by operation.
    Therapia Hungarica (English edition), 1988, Volume: 36, Issue:3

    Topics: Adult; Domperidone; Dyspepsia; Female; Humans; Middle Aged; Nausea; Postoperative Complications; Pre

1988
Dopamine antagonist domperidone (Motilium) in everyday clinical practice.
    Therapia Hungarica (English edition), 1988, Volume: 36, Issue:4

    Topics: Adult; Aged; Domperidone; Dyspepsia; Female; Humans; Male; Middle Aged; Nausea; Vomiting

1988
Use of peripheral dopamine receptor antagonist in gynaecology in certain borderline cases.
    Therapia Hungarica (English edition), 1987, Volume: 35, Issue:1

    Topics: Climacteric; Domperidone; Dyspepsia; Female; Gastrointestinal Diseases; Humans; Migraine Disorders;

1987
[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Drug Evaluation; Female; H

1986
Pharmacological exploration of dopamine hypersensitivity in migraine patients.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:3

    Topics: Cerebrovascular Circulation; Domperidone; Dopamine; Headache; Humans; Hypotension; Migraine Disorder

1986
Cardiac arrest after treatment with intravenous domperidone.
    British medical journal (Clinical research ed.), 1985, Jan-12, Volume: 290, Issue:6462

    Topics: Antineoplastic Agents; Domperidone; Heart Arrest; Humans; Nausea

1985
Domperidone.
    British medical journal (Clinical research ed.), 1985, Jan-19, Volume: 290, Issue:6463

    Topics: Domperidone; Humans; Nausea; Parkinson Disease

1985
[Effect of combined use of adrenocortical hormones and domperidone as anti-emetics during cisplatin therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Cisplatin; Domperidone; Drug Therapy, Combination; Esophageal Neoplas

1985
A pilot study of high-dose domperidone as an antiemetic in patients treated with cisplatin.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:7

    Topics: Adolescent; Adult; Aged; Cisplatin; Domperidone; Female; Humans; Infusions, Parenteral; Male; Middle

1985