Page last updated: 2024-10-26

domperidone and Muscle Relaxation

domperidone has been researched along with Muscle Relaxation in 8 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, C1
Qian, W1
Hou, X1
Sahyoun, HA1
Costall, B2
Naylor, RJ2
Tan, CC1
Brock-Utne, JG1
Lefebvre, RA1
Willems, JL1
Yamauchi, M1
Kobayashi, Y1
Hattori, K1
Yamada, K1
Nakase, A1
Lombardi, DM1
Grous, M1
Fine, CF1
Barone, FC1
Fowler, PJ1
Phyall, WB1
Rush, JA1
Ormsbee, HS1
Schuurkes, JA1
Helsen, LF1
Van Nueten, JM1

Trials

1 trial available for domperidone and Muscle Relaxation

ArticleYear
Domperidone antagonizes the relaxant effect atropine on the lower esophageal sphincter.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:12

    Topics: Adult; Antiemetics; Atropine; Benzimidazoles; Domperidone; Esophagogastric Junction; Gastroesophagea

1980

Other Studies

7 other studies available for domperidone and Muscle Relaxation

ArticleYear
Effect of four medications associated with gastrointestinal motility on Oddi sphincter in the rabbit.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2009, Volume: 9, Issue:5

    Topics: Animals; Carbachol; Domperidone; Gastrointestinal Agents; Gastrointestinal Motility; Indoles; Male;

2009
On the ability of domperidone to selectively inhibit catecholamine-induced relaxation of circular smooth muscle of guinea-pig stomach.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:1

    Topics: Animals; Catecholamines; Domperidone; Dopamine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Mal

1982
Neuronally mediated contraction responses of guinea-pig stomach smooth muscle preparations: modification by benzamide derivatives does not reflect a dopamine antagonist action.
    European journal of pharmacology, 1984, Jun-15, Volume: 102, Issue:1

    Topics: Animals; Benzamides; Domperidone; Electric Stimulation; Guinea Pigs; Haloperidol; In Vitro Technique

1984
Gastric relaxation by morphine, apomorphine and fentanyl in the conscious dog.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 242, Issue:2

    Topics: Animals; Apomorphine; Benzimidazoles; Dogs; Domperidone; Fentanyl; Haloperidol; Morphine; Muscle Con

1979
Dopamine-induced relaxation in human pulmonary arteries.
    Experientia, 1989, Feb-15, Volume: 45, Issue:2

    Topics: Aged; Dinoprost; Domperidone; Dopamine; Female; Fluphenazine; Haloperidol; Humans; Male; Middle Aged

1989
DA1 receptor mediates dopamine-induced relaxation of opossum lower esophageal sphincter in vitro.
    Gastroenterology, 1986, Volume: 91, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Aporphines; Benzaz

1986
A comparative study on the effects of domperidone, metoclopramide, clebopride and trimebutine on the gastro-duodenal preparation of the guinea pig.
    Japanese journal of pharmacology, 1985, Volume: 39, Issue:2

    Topics: Animals; Benzamides; Benzoates; Domperidone; Drug Antagonism; Duodenum; Female; Gastrointestinal Mot

1985