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domperidone and Multiple Sclerosis, Relapsing-Remitting

domperidone has been researched along with Multiple Sclerosis, Relapsing-Remitting in 1 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Multiple Sclerosis, Relapsing-Remitting: The most common clinical variant of MULTIPLE SCLEROSIS, characterized by recurrent acute exacerbations of neurologic dysfunction followed by partial or complete recovery. Common clinical manifestations include loss of visual (see OPTIC NEURITIS), motor, sensory, or bladder function. Acute episodes of demyelination may occur at any site in the central nervous system, and commonly involve the optic nerves, spinal cord, brain stem, and cerebellum. (Adams et al., Principles of Neurology, 6th ed, pp903-914)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koch, MW1
Liu, WQ1
Camara-Lemarroy, C1
Zhang, Y1
Pike, GB1
Metz, L1
Yong, VW1

Trials

1 trial available for domperidone and Multiple Sclerosis, Relapsing-Remitting

ArticleYear
Domperidone-induced elevation of serum prolactin levels and immune response in multiple sclerosis.
    Journal of neuroimmunology, 2019, 09-15, Volume: 334

    Topics: Adult; Biomarkers; Domperidone; Dopamine Antagonists; Female; Follow-Up Studies; Humans; Immunity, C

2019