Page last updated: 2024-10-26

domperidone and Lung Injury, Acute

domperidone has been researched along with Lung Injury, Acute in 1 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
"Domperidone treatment increased LPS-induced tumor necrosis factor (TNF) and interleukin (IL)-6 production in the bronchoalveolar lavage fluid, without altering tissue damage and the number of immune cells in the lungs and circulation."5.48Repeated Domperidone treatment modulates pulmonary cytokines in LPS-induced acute lung injury in mice. ( Barreto, TR; Costola-de-Souza, C; Felício, LF; Margatho, RO; Palermo-Neto, J; Queiroz-Hazarbassanov, N; Rodrigues, SC; Zager, A, 2018)
"Domperidone treatment increased LPS-induced tumor necrosis factor (TNF) and interleukin (IL)-6 production in the bronchoalveolar lavage fluid, without altering tissue damage and the number of immune cells in the lungs and circulation."1.48Repeated Domperidone treatment modulates pulmonary cytokines in LPS-induced acute lung injury in mice. ( Barreto, TR; Costola-de-Souza, C; Felício, LF; Margatho, RO; Palermo-Neto, J; Queiroz-Hazarbassanov, N; Rodrigues, SC; Zager, A, 2018)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barreto, TR1
Costola-de-Souza, C1
Margatho, RO1
Queiroz-Hazarbassanov, N1
Rodrigues, SC1
Felício, LF1
Palermo-Neto, J1
Zager, A1

Other Studies

1 other study available for domperidone and Lung Injury, Acute

ArticleYear
Repeated Domperidone treatment modulates pulmonary cytokines in LPS-induced acute lung injury in mice.
    International immunopharmacology, 2018, Volume: 56

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Progression; Domperidone; Dopamine

2018