Page last updated: 2024-10-26

domperidone and Liver Cirrhosis

domperidone has been researched along with Liver Cirrhosis in 4 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"The phenomenon of sudden cardiac death is usually related to the worsening of existing heart conditions leading to ventricular arrhythmia (VA)."1.42A case of sudden cardiac death following Domperidone self-medication. ( De Leo, D; Fais, P; Gottardo, R; Laposata, C; Lockwood, R; Vermiglio, E, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deng, JJ1
Fan, HM1
Zhang, AM1
Xie, M1
Tan, XH1
Fais, P1
Vermiglio, E1
Laposata, C1
Lockwood, R1
Gottardo, R1
De Leo, D1
Braillon, A1
Capron-Chivrac, D1
Valla, D1
Lee, SS1
Capron, JP1
Lebrec, D1
Sauerbruch, T1

Trials

1 trial available for domperidone and Liver Cirrhosis

ArticleYear
[Efficacy controlled observation on acupuncture and western medicine for gastrointestinal dysmotility in liver cirrhosis].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2013, Volume: 33, Issue:5

    Topics: Acupuncture Therapy; Adult; Aged; Domperidone; Female; Gastrointestinal Motility; Humans; Liver Cirr

2013

Other Studies

3 other studies available for domperidone and Liver Cirrhosis

ArticleYear
A case of sudden cardiac death following Domperidone self-medication.
    Forensic science international, 2015, Volume: 254

    Topics: Alcoholism; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Domperidone; Female; Gastrointestinal Agen

2015
Domperidone-induced increase in lower oesophageal sphincter pressure does not affect azygos blood flow in patients with cirrhosis.
    Scandinavian journal of gastroenterology, 1986, Volume: 21, Issue:9

    Topics: Domperidone; Esophageal and Gastric Varices; Esophagogastric Junction; Gastrointestinal Hemorrhage;

1986
[Commentary on an abstract. Effects of metoclopramide and domperidone on azygous venous blood flow in patients with cirrhosis and portal hypertension].
    Zeitschrift fur Gastroenterologie, 1987, Volume: 25, Issue:9

    Topics: Azygos Vein; Domperidone; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Liver Circul

1987