Page last updated: 2024-10-26

domperidone and Labor, Premature

domperidone has been researched along with Labor, Premature in 1 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
"To investigate the possibility of a dose-response relationship for the use of domperidone in treating insufficient milk supply in mothers of preterm infants, and to quantify the exposure of the breastfed infant to domperidone."2.73Dose-effect study of domperidone as a galactagogue in preterm mothers with insufficient milk supply, and its transfer into milk. ( Davey, K; Hartmann, PE; Ilett, KF; Page-Sharp, M; Simmer, K; Wan, EW, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wan, EW1
Davey, K1
Page-Sharp, M1
Hartmann, PE1
Simmer, K1
Ilett, KF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Clinical Trial: Use of Domperidone to Increase Milk Production in Mothers With Newborns Hospitalized in Neonatology[NCT03221855]Early Phase 130 participants (Actual)Interventional2013-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for domperidone and Labor, Premature

ArticleYear
Dose-effect study of domperidone as a galactagogue in preterm mothers with insufficient milk supply, and its transfer into milk.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:2

    Topics: Breast Feeding; Clinical Protocols; Domperidone; Dopamine Antagonists; Dose-Response Relationship, D

2008