domperidone has been researched along with Irritable Bowel Syndrome in 2 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin attenuated the visceral allodynia and increased gut permeability in animal IBS models." | 7.91 | Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats. ( Kumei, S; Miyagishi, S; Nozu, R; Nozu, T; Okumura, T; Takakusaki, K, 2019) |
| "Metformin attenuated the visceral allodynia and increased gut permeability in animal IBS models." | 3.91 | Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats. ( Kumei, S; Miyagishi, S; Nozu, R; Nozu, T; Okumura, T; Takakusaki, K, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Madisch, A | 1 |
| Vinson, BR | 1 |
| Abdel-Aziz, H | 1 |
| Kelber, O | 1 |
| Nieber, K | 1 |
| Kraft, K | 1 |
| Storr, M | 1 |
| Nozu, T | 1 |
| Miyagishi, S | 1 |
| Kumei, S | 1 |
| Nozu, R | 1 |
| Takakusaki, K | 1 |
| Okumura, T | 1 |
1 review available for domperidone and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Modulation of gastrointestinal motility beyond metoclopramide and domperidone : Pharmacological and clinical evidence for phytotherapy in functional gastrointestinal disorders.
Topics: Domperidone; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Irritable Bowel Syndrome; | 2017 |
1 other study available for domperidone and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats.
Topics: AMP-Activated Protein Kinases; Animals; Colon; Disease Models, Animal; Domperidone; Dopamine Antagon | 2019 |