domperidone has been researched along with Intraocular Pressure in 5 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone, a dopamine antagonist was found to delay the intraocular pressure (IOP) recovery in rabbit eyes after infusion with hypertonic saline and to lower the IOP of normal cat eyes, indicating that domperidone is an ocular hypotensive agent." | 7.67 | Reduction of intraocular pressure by domperidone. ( Chiou, GC, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Potter, DE | 2 |
| Burke, JA | 1 |
| Chang, FW | 1 |
| Ogidigben, MJ | 1 |
| Heath, AR | 1 |
| Chiou, GC | 2 |
| Chen, YJ | 1 |
| al-Sereiti, MR | 1 |
| Quik, RF | 1 |
| Hedges, A | 1 |
| Turner, P | 1 |
1 trial available for domperidone and Intraocular Pressure
| Article | Year |
|---|---|
Antagonism by domperidone of the ocular hypotensive effect of pergolide.
Topics: Adult; Domperidone; Female; Humans; Intraocular Pressure; Male; Pergolide; Regression Analysis | 1990 |
4 other studies available for domperidone and Intraocular Pressure
| Article | Year |
|---|---|
Ocular hypotensive action of ergoline derivatives in rabbits: effects of sympathectomy and domperidone pretreatment.
Topics: Administration, Topical; Animals; Bromocriptine; Domperidone; Ergolines; Eye; Ganglia, Sympathetic; | 1984 |
Ocular actions of an octahydrobenzo[f]quinoline: Ha117.
Topics: Animals; Aqueous Humor; Cats; Ciliary Body; Cyclic AMP; Domperidone; Dopamine Agents; Electric Stimu | 1993 |
Effects of dopamine agonist, bromocriptine, and some dopamine antagonists on ocular blood flow.
Topics: Animals; Blood Flow Velocity; Bromocriptine; Disease Models, Animal; Domperidone; Dopamine Antagonis | 1992 |
Reduction of intraocular pressure by domperidone.
Topics: Animals; Cats; Domperidone; Female; Intraocular Pressure; Male; Rabbits | 1986 |