domperidone has been researched along with Intestinal Diseases in 6 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone has been used as a gastrokinetic and anti-emetic drug within the frames of an intensive care programme in 57 patients with a history of 3-4 days of acute myocardial infarction." | 9.07 | Role of domperidone in improving intestinal activity in acute myocardial infarction patients. ( Lencz, L, 1991) |
| "Indomethacin treatment markedly enhanced inducible nitric oxide synthase and chemokine mRNA expression in the small intestine, but these responses were all significantly attenuated by either domperidone or metoclopramide." | 5.37 | Dopamine D₂-receptor antagonists ameliorate indomethacin-induced small intestinal ulceration in mice by activating α7 nicotinic acetylcholine receptors. ( Amagase, K; Hashimura, H; Iimori, M; Kato, S; Kawahara, R; Takeuchi, K; Yamanaka, N; Yasuda, M, 2011) |
| "Domperidone has been used as a gastrokinetic and anti-emetic drug within the frames of an intensive care programme in 57 patients with a history of 3-4 days of acute myocardial infarction." | 5.07 | Role of domperidone in improving intestinal activity in acute myocardial infarction patients. ( Lencz, L, 1991) |
| "Indomethacin treatment markedly enhanced inducible nitric oxide synthase and chemokine mRNA expression in the small intestine, but these responses were all significantly attenuated by either domperidone or metoclopramide." | 1.37 | Dopamine D₂-receptor antagonists ameliorate indomethacin-induced small intestinal ulceration in mice by activating α7 nicotinic acetylcholine receptors. ( Amagase, K; Hashimura, H; Iimori, M; Kato, S; Kawahara, R; Takeuchi, K; Yamanaka, N; Yasuda, M, 2011) |
| " twice, 30 min before each dosing of dopamine." | 1.32 | Dopamine-induced protection against indomethacin-evoked intestinal lesions in rats--role of anti-intestinal motility mediated by D2 receptors. ( Kato, S; Matsumoto, M; Miyazawa, T; Takeuchi, K, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dias de Castro, F | 1 |
| Rosa, B | 1 |
| Moreira, MJ | 1 |
| Magalhães, J | 1 |
| Cotter, J | 1 |
| Yasuda, M | 1 |
| Kawahara, R | 1 |
| Hashimura, H | 1 |
| Yamanaka, N | 1 |
| Iimori, M | 1 |
| Amagase, K | 1 |
| Kato, S | 2 |
| Takeuchi, K | 2 |
| Miyazawa, T | 1 |
| Matsumoto, M | 1 |
| Lencz, L | 1 |
| Layer, P | 1 |
| Goebell, H | 1 |
| Reynolds, JC | 1 |
1 review available for domperidone and Intestinal Diseases
| Article | Year |
|---|---|
Prokinetic agents: a key in the future of gastroenterology.
Topics: Biomechanical Phenomena; Cisapride; Domperidone; Forecasting; Gastroenterology; Gastroesophageal Ref | 1989 |
1 trial available for domperidone and Intestinal Diseases
| Article | Year |
|---|---|
Role of domperidone in improving intestinal activity in acute myocardial infarction patients.
Topics: Adult; Aged; Aged, 80 and over; Domperidone; Female; Gastrointestinal Motility; Humans; Intestinal D | 1991 |
4 other studies available for domperidone and Intestinal Diseases
| Article | Year |
|---|---|
The role of domperidone in increasing the completion rate of small bowel capsule endoscopy: how should it be used?
Topics: Capsule Endoscopy; Domperidone; Dopamine Antagonists; Female; Humans; Intestinal Diseases; Male | 2015 |
Dopamine D₂-receptor antagonists ameliorate indomethacin-induced small intestinal ulceration in mice by activating α7 nicotinic acetylcholine receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulce | 2011 |
Dopamine-induced protection against indomethacin-evoked intestinal lesions in rats--role of anti-intestinal motility mediated by D2 receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Domperidon | 2003 |
[Therapy of motility disorders of the stomach and small intestine].
Topics: Cisapride; Constipation; Diarrhea; Domperidone; Dumping Syndrome; Gastric Emptying; Gastrointestinal | 1991 |