domperidone has been researched along with Inflammation in 4 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inflammatory edema was induced by carrageenan in male rats, and hyperprolactinemia was induced by injections of the dopamine receptor antagonist domperidone." | 3.76 | Acute and chronic stress and the inflammatory response in hyperprolactinemic rats. ( Carvalho-Freitas, MI; Cruz-Casallas, PE; Felicio, LF; Malucelli, BE; Nasello, AG; Ochoa-Amaya, JE, 2010) |
| "PRL deficiency accelerated liver carcinogenesis in Prl(-/-) mice of both sexes." | 1.40 | Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice. ( Fox, JG; Hartwell, HJ; Horseman, ND; Petrosky, KY; Rogers, AB, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Li, T | 1 |
| Wang, L | 1 |
| Zhang, L | 2 |
| Li, B | 1 |
| Wang, D | 1 |
| Wang, T | 1 |
| Fu, F | 1 |
| Hartwell, HJ | 1 |
| Petrosky, KY | 1 |
| Fox, JG | 1 |
| Horseman, ND | 1 |
| Rogers, AB | 1 |
| Ochoa-Amaya, JE | 1 |
| Malucelli, BE | 1 |
| Cruz-Casallas, PE | 1 |
| Nasello, AG | 1 |
| Felicio, LF | 1 |
| Carvalho-Freitas, MI | 1 |
4 other studies available for domperidone and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Rotigotine-loaded microspheres exerts the antinociceptive effect via central dopaminergic system.
Topics: Analgesics; Animals; Carrageenan; Corpus Striatum; Disease Models, Animal; Domperidone; Dopamine; Do | 2021 |
Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice.
Topics: Adult; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Domperidone; Female; Humans; Immunity, In | 2014 |
Acute and chronic stress and the inflammatory response in hyperprolactinemic rats.
Topics: Acute Disease; Animals; Carrageenan; Chronic Disease; Cold Temperature; Disease Models, Animal; Domp | 2010 |