domperidone has been researched along with Hypothermia in 2 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "0 mg/kg, ip) hypothermia was reversed by the central and peripheral administration of the D2 antagonists S-(-)-sulpiride (3." | 3.68 | Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists. ( Michel, AD; Nunes, JL; Sharif, NA; Whiting, RL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Varty, GB | 1 |
| Higgins, GA | 1 |
| Nunes, JL | 1 |
| Sharif, NA | 1 |
| Michel, AD | 1 |
| Whiting, RL | 1 |
2 other studies available for domperidone and Hypothermia
| Article | Year |
|---|---|
Dopamine agonist-induced hypothermia and disruption of prepulse inhibition: evidence for a role of D3 receptors?
Topics: Animals; Body Temperature; Cocaine; Domperidone; Dopamine Agonists; Dopamine Antagonists; Dopamine U | 1998 |
Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Body Temperature | 1991 |