Page last updated: 2024-10-26

domperidone and Hypotension

domperidone has been researched along with Hypotension in 8 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"To assess the role of spinal dopamine receptors in mediation of hypotension induced by systemic administration of the dopamine D2 receptor agonist, bromocriptine, conscious deoxycorticosterone acetate (DOCA)-salt hypertensive rats were pretreated with either intravenous (i."3.70Hypotensive action of bromocriptine in the DOCA-salt hypertensive rat: contribution of spinal dopamine receptors. ( Duarte, GP; Lahlou, S, 1998)
"Migraine suffers who experience spontaneous syncopes (syncopal migraine) during attacks exhibit a dramatic intolerance to bromocriptine, a dopamine agonist."3.66A new nonvascular interpretation of syncopal migraine. ( Boccuni, M; Bonciani, M; D'Egidio, P; Fanciullacci, M; Sicuteri, F, 1982)
"propranolol treatment."1.28Increase in the hypotensive effect of bromocriptine induced by spinal transection in rats: contribution of spinal dopamine receptors. ( Demenge, P; Lahlou, S, 1992)
"Patients with migraine show a hypersensitivity to dopamine or its agonists."1.27Pharmacological exploration of dopamine hypersensitivity in migraine patients. ( Bès, A; Bessoles, G; Dupui, P; Géraud, G; Güell, A, 1986)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lahlou, S4
Sicuteri, F1
Boccuni, M1
Fanciullacci, M1
D'Egidio, P1
Bonciani, M1
Pollak, P1
Gaio, JM1
Chateau, R1
Duarte, GP1
Demenge, P1
Bès, A1
Dupui, P1
Güell, A1
Bessoles, G1
Géraud, G1
Lahiri, S1
Hsiao, C1
Zhang, R1
Mokashi, A1
Nishino, T1

Other Studies

8 other studies available for domperidone and Hypotension

ArticleYear
Enhanced hypotensive response to intravenous apomorphine in chronic spinalized, conscious rats: role of spinal dopamine D(1) and D(2) receptors.
    Neuroscience letters, 2003, Oct-02, Volume: 349, Issue:2

    Topics: Animals; Apomorphine; Benzazepines; Blood Pressure; Consciousness; Domperidone; Dopamine Agonists; D

2003
A new nonvascular interpretation of syncopal migraine.
    Advances in neurology, 1982, Volume: 33

    Topics: Adolescent; Adult; Blood Pressure; Bromocriptine; Domperidone; Female; Humans; Hypotension; Male; Mi

1982
[Prevention by domperidone of arterial hypotension induced by bromocriptine].
    La Nouvelle presse medicale, 1981, Oct-31, Volume: 10, Issue:39

    Topics: Bromocriptine; Domperidone; Humans; Hypotension; Middle Aged

1981
Involvement of spinal dopamine receptors in mediation of the hypotensive and bradycardic effects of systemic quinpirole in anaesthetised rats.
    European journal of pharmacology, 1998, Jul-24, Volume: 353, Issue:2-3

    Topics: Animals; Bradycardia; Domperidone; Dopamine Agonists; Dose-Response Relationship, Drug; Hypotension;

1998
Hypotensive action of bromocriptine in the DOCA-salt hypertensive rat: contribution of spinal dopamine receptors.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bromocriptine; Desoxycorticosterone;

1998
Increase in the hypotensive effect of bromocriptine induced by spinal transection in rats: contribution of spinal dopamine receptors.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:5

    Topics: Analysis of Variance; Animals; Blood Pressure; Blood-Brain Barrier; Bromocriptine; Domperidone; Hear

1992
Pharmacological exploration of dopamine hypersensitivity in migraine patients.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:3

    Topics: Cerebrovascular Circulation; Domperidone; Dopamine; Headache; Humans; Hypotension; Migraine Disorder

1986
Peripheral chemoreceptors in respiratory oscillations.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:6

    Topics: Animals; Blood Pressure; Carotid Body; Cats; Domperidone; Feedback; Heart Rate; Hypotension; Oxygen;

1985