domperidone has been researched along with Hyperoxia in 7 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Hyperoxia: An abnormal increase in the amount of oxygen in the tissues and organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have studied the ventilatory responses to transient hyperoxia in two groups of patients (n = 10) anaesthetized with isoflurane (0." | 9.08 | Effect of domperidone on the ventilatory response to transient hyperoxia in patients anaesthetized with isoflurane. ( Drummond, GB; Foo, IT; Warren, PM, 1997) |
| " Exposure to moderate and severe hypoxia as well as to hyperoxia and injection of domperidone, a potent peripheral ventilatory stimulant, revealed that the presence of transgenic or rhEpo extensively increased the hypoxic ventilatory response in female mice compared with their corresponding male siblings." | 3.75 | Sex-dependent regulation of hypoxic ventilation in mice and humans is mediated by erythropoietin. ( Gassmann, M; Lundby, C; Soliz, J; Soulage, C; Thomsen, JJ, 2009) |
| " Peripheral chemoreceptor effects on ventilation were evaluated by exposing animals to hyperoxia (Dejours test) and domperidone, a peripheral ventilatory stimulant drug directly affecting the carotid sinus nerve discharge." | 3.74 | Ventilatory responses to acute and chronic hypoxia are altered in female but not male Paskin-deficient mice. ( Borter, E; Gassmann, M; Soliz, J; Soulage, C; van Patot, MT, 2008) |
| "Domperidone caused an increase in CSN activity at all O2 levels in adults (P < 0." | 1.29 | Effects of domperidone on neonatal and adult carotid chemoreceptors in the cat. ( Bamford, OS; Carroll, JL; Fitzgerald, RS; Sterni, LM; Tomares, SM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soliz, J | 2 |
| Soulage, C | 2 |
| Borter, E | 1 |
| van Patot, MT | 1 |
| Gassmann, M | 2 |
| Thomsen, JJ | 1 |
| Lundby, C | 1 |
| Batuca, JR | 1 |
| Monteiro, TC | 1 |
| Monteiro, EC | 1 |
| Tomares, SM | 1 |
| Bamford, OS | 1 |
| Sterni, LM | 1 |
| Fitzgerald, RS | 1 |
| Carroll, JL | 1 |
| Foo, IT | 1 |
| Warren, PM | 1 |
| Drummond, GB | 1 |
| Huey, KA | 1 |
| Brown, IP | 1 |
| Jordan, MC | 1 |
| Powell, FL | 1 |
| Nakano, H | 1 |
| Lee, SD | 1 |
| Farkas, GA | 1 |
1 trial available for domperidone and Hyperoxia
| Article | Year |
|---|---|
Effect of domperidone on the ventilatory response to transient hyperoxia in patients anaesthetized with isoflurane.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Chemoreceptor Cells; Domperidone; Dopamine Antagon | 1997 |
6 other studies available for domperidone and Hyperoxia
| Article | Year |
|---|---|
Ventilatory responses to acute and chronic hypoxia are altered in female but not male Paskin-deficient mice.
Topics: Acclimatization; Acute Disease; Animals; Body Temperature; Carotid Body; Chronic Disease; Disease Mo | 2008 |
Sex-dependent regulation of hypoxic ventilation in mice and humans is mediated by erythropoietin.
Topics: Adaptation, Physiological; Adult; Animals; Brain Stem; Catecholamines; Disease Models, Animal; Dompe | 2009 |
Contribution of dopamine D2 receptors for the cAMP levels at the carotid body.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carotid Body; Colforsin; Cyclic AMP; Domperidone; Dopamine; Fe | 2003 |
Effects of domperidone on neonatal and adult carotid chemoreceptors in the cat.
Topics: Animals; Carbon Dioxide; Carotid Body; Carotid Sinus; Cats; Domperidone; Dopamine Antagonists; Elect | 1994 |
Changes in dopamine D(2)-receptor modulation of the hypoxic ventilatory response with chronic hypoxia.
Topics: Animals; Carbon Dioxide; Carotid Body; Central Nervous System; Domperidone; Dopamine Antagonists; Do | 2000 |
Dopaminergic modulation of ventilation in obese Zucker rats.
Topics: Animals; Body Temperature; Domperidone; Dopamine; Dopamine Antagonists; Haloperidol; Hypercapnia; Hy | 2002 |