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domperidone and Hypergonadotropic Hypogonadism

domperidone has been researched along with Hypergonadotropic Hypogonadism in 1 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
"In order to test whether prolactin response to challenge with TRH and domperidone, dopamine receptor antagonist, is diagnostic for idiopathic hypothalamic hypogonadism (IHH) we studied 8 normal controls, 9 subjects with delayed sexual development and 6 patients with IHH."7.67The prolactin response to TRH and domperidone does not differentiate male hypothalamic hypogonadism and constitutional delay of puberty. ( Djordjević, A; Kendereski, A; Manojlović, D; Mićić, D; Mićić, J; Milosević, Z; Nesović, M; Popović, V; Radmanović, S, 1987)
"In order to test whether prolactin response to challenge with TRH and domperidone, dopamine receptor antagonist, is diagnostic for idiopathic hypothalamic hypogonadism (IHH) we studied 8 normal controls, 9 subjects with delayed sexual development and 6 patients with IHH."3.67The prolactin response to TRH and domperidone does not differentiate male hypothalamic hypogonadism and constitutional delay of puberty. ( Djordjević, A; Kendereski, A; Manojlović, D; Mićić, D; Mićić, J; Milosević, Z; Nesović, M; Popović, V; Radmanović, S, 1987)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Popović, V1
Milosević, Z1
Mićić, D1
Nesović, M1
Radmanović, S1
Kendereski, A1
Djordjević, A1
Manojlović, D1
Mićić, J1

Other Studies

1 other study available for domperidone and Hypergonadotropic Hypogonadism

ArticleYear
The prolactin response to TRH and domperidone does not differentiate male hypothalamic hypogonadism and constitutional delay of puberty.
    Experimental and clinical endocrinology, 1987, Volume: 89, Issue:2

    Topics: Adolescent; Adult; Diagnosis, Differential; Domperidone; Gonadotropin-Releasing Hormone; Humans; Hyp

1987