domperidone has been researched along with Hypercapnia in 10 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In one series, we simultaneously measured carotid chemoreceptor and ventilatory responses to hypoxia and hypercapnia before and after a saturation dose of intravenous domperidone, a peripheral dopamine (D2) receptor antagonist." | 3.67 | Peripheral and central dopamine receptors in respiratory control. ( Hsiao, C; Lahiri, S; Mokashi, A, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nemati, S | 1 |
| Edwards, BA | 1 |
| Sands, SA | 1 |
| Berger, PJ | 1 |
| Wellman, A | 1 |
| Verghese, GC | 1 |
| Malhotra, A | 1 |
| Butler, JP | 1 |
| Kim, DK | 1 |
| Prabhakar, NR | 1 |
| Kumar, GK | 1 |
| Subramanian, S | 1 |
| Dostal, J | 1 |
| Erokwu, B | 1 |
| Han, F | 1 |
| Dick, TE | 1 |
| Strohl, KP | 1 |
| Tatsumi, K | 1 |
| Pickett, CK | 1 |
| Weil, JV | 1 |
| Osanai, S | 1 |
| Akiba, Y | 1 |
| Fujiuchi, S | 1 |
| Nakano, H | 2 |
| Matsumoto, H | 1 |
| Ohsaki, Y | 1 |
| Kikuchi, K | 1 |
| Lee, SD | 1 |
| Farkas, GA | 1 |
| Javaheri, S | 1 |
| Guerra, LF | 1 |
| McQueen, DS | 1 |
| Evrard, Y | 1 |
| Gordon, BH | 1 |
| Campbell, DB | 1 |
| Hsiao, C | 1 |
| Lahiri, S | 1 |
| Mokashi, A | 1 |
| Kressin, NA | 1 |
| Nielsen, AM | 1 |
| Laravuso, R | 1 |
| Bisgard, GE | 1 |
2 trials available for domperidone and Hypercapnia
| Article | Year |
|---|---|
Depression of peripheral chemosensitivity by a dopaminergic mechanism in patients with obstructive sleep apnoea syndrome.
Topics: Adult; Aged; Chemoreceptor Cells; Domperidone; Dopamine; Dopamine Antagonists; Double-Blind Method; | 1999 |
Effects of domperidone and medroxyprogesterone acetate on ventilation in man.
Topics: Adult; Carotid Body; Chemoreceptor Cells; Domperidone; Double-Blind Method; Drug Interactions; Human | 1990 |
8 other studies available for domperidone and Hypercapnia
| Article | Year |
|---|---|
Model-based characterization of ventilatory stability using spontaneous breathing.
Topics: Animals; Animals, Newborn; Apnea; Carbon Dioxide; Carotid Body; Domperidone; Dopamine Antagonists; D | 2011 |
Acetylcholine release from the carotid body by hypoxia: evidence for the involvement of autoinhibitory receptors.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carotid Body; Domperidone; Dopamine Antagoni | 2004 |
Domperidone and ventilatory behavior: Sprague-Dawley versus Brown Norway rats.
Topics: Animals; Behavior, Animal; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Enzy | 2007 |
Possible role of dopamine in ventilatory acclimatization to high altitude.
Topics: Acclimatization; Altitude; Animals; Body Weight; Cats; Domperidone; Dopamine; Female; Hypercapnia; H | 1995 |
Dopaminergic modulation of ventilation in obese Zucker rats.
Topics: Animals; Body Temperature; Domperidone; Dopamine; Dopamine Antagonists; Haloperidol; Hypercapnia; Hy | 2002 |
Ganglioglomerular nerves influence responsiveness of cat carotid body chemoreceptors to almitrine.
Topics: Action Potentials; Adrenergic Fibers; Almitrine; Animals; Carotid Body; Cats; Chemoreceptor Cells; D | 1989 |
Peripheral and central dopamine receptors in respiratory control.
Topics: Animals; Carotid Body; Cats; Domperidone; Dopamine; Female; Haloperidol; Hypercapnia; Hypoxia; Recep | 1989 |
Domperidone-induced potentiation of ventilatory responses in awake goats.
Topics: Animals; Carotid Body; Denervation; Domperidone; Dopamine Antagonists; Goats; Hypercapnia; Hypoxia; | 1986 |