domperidone has been researched along with Heartburn in 4 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Heartburn: Substernal pain or burning sensation, usually associated with regurgitation of gastric juice into the esophagus.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Among all 8 subjects, 4 reported heartburn after taking lubiprostone, whereas this symptom was not found when subjects received concomitant domperidone." | 5.24 | Impact of lubiprostone on gastric-emptying profile and the possible effect of concomitant domperidone in healthy adults . ( Abe, K; Kimura, S; Kita, H; Miki, A; Okamura, T; Yamamoto, T, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okamura, T | 1 |
| Yamamoto, T | 1 |
| Kimura, S | 1 |
| Miki, A | 1 |
| Abe, K | 1 |
| Kita, H | 1 |
| Ndraha, S | 1 |
| Brock-Utne, JG | 1 |
| Downing, JW | 1 |
| Dimopoulos, GE | 1 |
| Rubin, J | 1 |
| Moshal, MG | 1 |
| Angelini, G | 1 |
| Castagnini, A | 1 |
| Rizzoli, R | 1 |
| Pasini, AF | 1 |
| Lavarini, E | 1 |
| Brocco, G | 1 |
| Scuro, LA | 1 |
3 trials available for domperidone and Heartburn
| Article | Year |
|---|---|
Impact of lubiprostone on gastric-emptying profile and the possible effect of concomitant domperidone in healthy adults
.
Topics: Adult; Antiemetics; Breath Tests; Chloride Channel Agonists; Domperidone; Drug Interactions; Gastric | 2017 |
Combination of PPI with a prokinetic drug in gastroesophageal reflux disease.
Topics: Administration, Oral; Adult; Antiemetics; Domperidone; Double-Blind Method; Drug Synergism; Drug The | 2011 |
Treatment of reflux gastritis: double blind comparison between clebopride and domperidone. A preliminary report.
Topics: Adolescent; Adult; Aged; Antiemetics; Benzamides; Bile Acids and Salts; Domperidone; Double-Blind Me | 1990 |
1 other study available for domperidone and Heartburn
| Article | Year |
|---|---|
Effect of domperidone on lower esophageal sphincter tone in late pregnancy.
Topics: Adolescent; Adult; Anesthesia, Obstetrical; Benzimidazoles; Domperidone; Esophagogastric Junction; F | 1980 |