domperidone has been researched along with Headache in 8 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is increased awareness about risks and benefits of using domperidone to treat gastroparesis." | 7.83 | Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016) |
| "To determine the safety of domperidone in the treatment of nausea associated with dihydroergotamine (DHE) infusion and headache." | 7.83 | Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache. ( Goadsby, PJ; Ito, H; Robbins, NM; Scheinman, MM, 2016) |
| "Etiology identification of the stroke included cardiogenic pathology and coagulopathy, but acitretin treatment was considered the likeliest explanation." | 7.71 | Acitretin-associated thrombotic stroke. ( Davani, S; Kantelip, JP; Muret, P; Royer, B; Ziegler, F, 2002) |
| "There is increased awareness about risks and benefits of using domperidone to treat gastroparesis." | 3.83 | Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016) |
| "To determine the safety of domperidone in the treatment of nausea associated with dihydroergotamine (DHE) infusion and headache." | 3.83 | Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache. ( Goadsby, PJ; Ito, H; Robbins, NM; Scheinman, MM, 2016) |
| "Domperidone is a dopamine antagonist that has recently been released in Canada." | 3.76 | Domperidone, a new dopamine antagonist. ( Champion, MC; Hartnett, M; Yen, M, 1986) |
| "Etiology identification of the stroke included cardiogenic pathology and coagulopathy, but acitretin treatment was considered the likeliest explanation." | 3.71 | Acitretin-associated thrombotic stroke. ( Davani, S; Kantelip, JP; Muret, P; Royer, B; Ziegler, F, 2002) |
| "Cephalalgias are divided into four syndromes and the most severe of these, migraine, presents several therapeutic applications." | 2.38 | [Therapy of headache]. ( Cavanna, M, 1989) |
| "Patients with migraine show a hypersensitivity to dopamine or its agonists." | 1.27 | Pharmacological exploration of dopamine hypersensitivity in migraine patients. ( Bès, A; Bessoles, G; Dupui, P; Géraud, G; Güell, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braillon, A | 1 |
| Robbins, NM | 2 |
| Goadsby, PJ | 2 |
| Schey, R | 1 |
| Saadi, M | 1 |
| Midani, D | 1 |
| Roberts, AC | 1 |
| Parupalli, R | 1 |
| Parkman, HP | 1 |
| Ito, H | 1 |
| Scheinman, MM | 1 |
| Royer, B | 1 |
| Ziegler, F | 1 |
| Muret, P | 1 |
| Davani, S | 1 |
| Kantelip, JP | 1 |
| Cavanna, M | 1 |
| Champion, MC | 1 |
| Hartnett, M | 1 |
| Yen, M | 1 |
| Bès, A | 1 |
| Dupui, P | 1 |
| Güell, A | 1 |
| Bessoles, G | 1 |
| Géraud, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oral Domperidone for Relief of Gastrointestinal Disorders in Patients Who Failed Standard Therapy[NCT00761254] | 42 participants (Actual) | Interventional | 2008-08-31 | Terminated (stopped due to PI withdrew due to increased responsibilities in clinical department.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for domperidone and Headache
| Article | Year |
|---|---|
[Therapy of headache].
Topics: Cluster Headache; Dextropropoxyphene; Dihydroergotamine; Domperidone; Ergotamine; Headache; Humans; | 1989 |
Domperidone, a new dopamine antagonist.
Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; Dys | 1986 |
1 trial available for domperidone and Headache
| Article | Year |
|---|---|
Domperidone, a new dopamine antagonist.
Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; Dys | 1986 |
6 other studies available for domperidone and Headache
| Article | Year |
|---|---|
Letter re: Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache.
Topics: Dihydroergotamine; Domperidone; Headache; Humans; Nausea | 2017 |
Author response: Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache.
Topics: Dihydroergotamine; Domperidone; Headache; Humans; Nausea | 2017 |
Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort.
Topics: Adult; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Diarrhea; Domperidone; Dopamine An | 2016 |
Safety of domperidone in treating nausea associated with dihydroergotamine infusion and headache.
Topics: Adolescent; Adult; Aged; Antiemetics; Dihydroergotamine; Domperidone; Female; Headache; Humans; Male | 2016 |
Acitretin-associated thrombotic stroke.
Topics: Acitretin; Analgesics; Anticoagulants; Antiemetics; Dextropropoxyphene; Domperidone; Female; Headach | 2002 |
Pharmacological exploration of dopamine hypersensitivity in migraine patients.
Topics: Cerebrovascular Circulation; Domperidone; Dopamine; Headache; Humans; Hypotension; Migraine Disorder | 1986 |