domperidone has been researched along with Galactorrhea in 9 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
Galactorrhea: Excessive or inappropriate LACTATION in females or males, and not necessarily related to PREGNANCY. Galactorrhea can occur either unilaterally or bilaterally, and be profuse or sparse. Its most common cause is HYPERPROLACTINEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Galactorrhea is a well-known side effect of domperidone, and is usually associated with hyperprolactinemia." | 7.81 | Euprolactinemic galactorrhea secondary to domperidone treatment. ( Berberoglu, M; Demir, AM; Kansu, A; Kuloglu, Z, 2015) |
| " Galactorrhea is a well-known side effect of domperidone, and is usually associated with hyperprolactinemia." | 3.81 | Euprolactinemic galactorrhea secondary to domperidone treatment. ( Berberoglu, M; Demir, AM; Kansu, A; Kuloglu, Z, 2015) |
| "The response to domperidone (a dopamine blocking agent) of serum prolactin (PRL) levels was compared in 3 patients with amenorrhea-galactorrhea without evidence of a pituitary tumor, 23 patients with prolactinomas (10 cases with histologic confirmation), 7 patients with histologically verified large nonfunctioning pituitary adenomas with normal or moderately elevated basal PRL levels, and 6 patients with histologically verified craniopharyngiomas (3 with normal basal PRL levels and 3 with elevated PRL levels)." | 3.67 | Dysfunction of dopaminergic regulation of prolactin in patients with functioning and nonfunctioning pituitary adenomas and craniopharyngiomas. ( Cornejo, J; Garza-Flores, J; Martinez-Campos, A; Velasco, F, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Demir, AM | 1 |
| Kuloglu, Z | 1 |
| Berberoglu, M | 1 |
| Kansu, A | 1 |
| De, S | 1 |
| Taylor, CM | 1 |
| Edwards, L | 1 |
| van der Steen, M | 1 |
| Du Caju, MV | 1 |
| Van Acker, KJ | 1 |
| Cann, PA | 1 |
| Read, NW | 1 |
| Holdsworth, CD | 1 |
| Maddern, GJ | 1 |
| Nijhawan, S | 1 |
| Rai, RR | 1 |
| Sharma, CM | 1 |
| Johnston, DG | 1 |
| Haigh, J | 1 |
| Prescott, RW | 1 |
| Heaton, A | 1 |
| Kendall-Taylor, P | 1 |
| Baylis, P | 1 |
| Alberti, KG | 1 |
| Rowe, R | 1 |
| Friesen, H | 1 |
| Cook, D | 1 |
| Martinez-Campos, A | 1 |
| Cornejo, J | 1 |
| Garza-Flores, J | 1 |
| Velasco, F | 1 |
1 trial available for domperidone and Galactorrhea
| Article | Year |
|---|---|
Galactorrhoea as side effect of domperidone.
Topics: Adult; Domperidone; Female; Galactorrhea; Humans; Lactation Disorders; Middle Aged; Pregnancy; Prola | 1983 |
8 other studies available for domperidone and Galactorrhea
| Article | Year |
|---|---|
Euprolactinemic galactorrhea secondary to domperidone treatment.
Topics: Adolescent; Antiemetics; Domperidone; Female; Galactorrhea; Gastroesophageal Reflux; Humans; Hyperpr | 2015 |
Domperidone toxicity in an infant on maintenance haemodialysis.
Topics: Domperidone; Dopamine Antagonists; Galactorrhea; Humans; Hyperprolactinemia; Infant; Kidney Failure, | 2007 |
Hyperprolactinaemia in a patient with cystic fibrosis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antiemetics; Cystic Fibrosis; Domperidone; Drug Combination | 2007 |
Gynecomastia in a male infant given domperidone.
Topics: Domperidone; Female; Galactorrhea; Gynecomastia; Humans; Infant; Male; Pregnancy; Vomiting | 1982 |
Galactorrhoea due to domperidone.
Topics: Adult; Domperidone; Female; Galactorrhea; Gastroesophageal Reflux; Humans; Lactation Disorders; Preg | 1983 |
Domperidone induced galactorrhea.
Topics: Adolescent; Domperidone; Dyspepsia; Female; Galactorrhea; Humans | 1991 |
Prolactin secretion and biological activity in females with galactorrhoea and normal circulating prolactin concentrations at rest.
Topics: Adult; Animals; Biological Assay; Domperidone; Female; Galactorrhea; Humans; Insulin; Lactation Diso | 1985 |
Dysfunction of dopaminergic regulation of prolactin in patients with functioning and nonfunctioning pituitary adenomas and craniopharyngiomas.
Topics: Adenoma; Adolescent; Adult; Amenorrhea; Craniopharyngioma; Domperidone; Dopamine; Female; Galactorrh | 1985 |