domperidone has been researched along with Experimental Radiation Injuries in 5 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Domperidone pretreatment prevented radiation-induced emesis in all of four dogs tested." | 1.27 | Radiation-induced emesis in the dog: effects of lesions and drugs. ( Briggs, DB; Carpenter, DO; Knox, AP; Strominger, NL, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dubois, A | 2 |
| Jacobus, JP | 1 |
| Grissom, MP | 1 |
| Eng, RR | 2 |
| Conklin, JJ | 2 |
| Danquechin Dorval, E | 1 |
| Mueller, GP | 1 |
| Durakovic, A | 1 |
| Carpenter, DO | 2 |
| Briggs, DB | 2 |
| Strominger, NL | 2 |
| King, GL | 1 |
| Knox, AP | 1 |
5 other studies available for domperidone and Experimental Radiation Injuries
| Article | Year |
|---|---|
Altered gastric emptying and prevention of radiation-induced vomiting in dogs.
Topics: Animals; Cobalt Radioisotopes; Dogs; Domperidone; Gastric Emptying; Male; Radiation Injuries, Experi | 1984 |
Effect of ionizing radiation on gastric secretion and gastric motility in monkeys.
Topics: Animals; beta-Endorphin; Domperidone; Electrophysiology; Endorphins; Fasting; Gastric Emptying; Gast | 1985 |
Mechanisms of radiation-induced emesis in the dog.
Topics: Animals; Dogs; Domperidone; Electrophysiology; Female; Indomethacin; Male; Radiation Injuries, Exper | 1988 |
Characterization of radiation-induced emesis in the ferret.
Topics: Animals; Apomorphine; Carnivora; Cobalt Radioisotopes; Domperidone; Emetics; Ferrets; Gamma Rays; Ma | 1988 |
Radiation-induced emesis in the dog: effects of lesions and drugs.
Topics: Animals; Apomorphine; Cerebral Ventricles; Dogs; Domperidone; Indomethacin; Neurons; Prostaglandins; | 1986 |