domperidone has been researched along with Emesis in 142 studies
Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this randomized, double-blind, phase 3 study, children ages 6 months to 12 years with acute gastroenteritis randomly (1:1) received oral domperidone 0." | 9.30 | Safety and Efficacy of Low-dose Domperidone for Treating Nausea and Vomiting Due to Acute Gastroenteritis in Children. ( Appiani, C; Garces-Sanchez, M; Gupta, R; Hu, P; Leitz, G; Li, Q; Mitha, E, 2019) |
| "Domperidone is an antiemetic that is often prescribed for children with acute gastroenteritis in Japan." | 9.20 | Domperidone with ORT in the treatment of pediatric acute gastroenteritis in Japan: a multicenter, randomized controlled trial. ( Hinotsu, S; Kawakami, K; Kishida, K; Kita, F; Nakahata, T; Sasaki, H; Shimakawa, T; Urushihara, H; Wakazono, Y; Yamauchi, E; Yorifuji, T, 2015) |
| "To compare the efficacy of ondansetron and domperidone for the symptomatic treatment of vomiting in children with AG who have failed ORT." | 9.15 | Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial. ( Arrighini, A; Bertolani, P; Biban, P; Bonati, M; Clavenna, A; Da Dalt, L; Di Pietro, P; Guala, A; Maestro, A; Mannelli, F; Marchetti, F; Messi, G; Pazzaglia, A; Perri, F; Reale, A; Renna, S; Ronfani, L; Rovere, F; Tondelli, MT; Urbino, AF; Valletta, E; Vitale, A; Zangardi, T; Zanon, D, 2011) |
| "We investigated the usefulness of concurrent therapy of granisetron with methylprednisolone sodium for on nausea, vomiting and anorexia induced by chemotherapy, including cisplatin, in patients with oral cancer." | 9.07 | [Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin]. ( Kawashima, T; Miyata, K; Morita, N; Ohmata, T; Sakamoto, T; Wada, T, 1993) |
| " CMF were included in a double-blind comparative study aimed at evaluating the efficacy of 3 different drugs (methylprednisolone (MP), metoclopramide (MTC), and domperidone (DMP) in preventing chemotherapy-induced nausea and vomiting." | 9.06 | Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF. ( Ballatori, E; Basurto, C; del Favero, A; Minotti, V; Roila, F; Tonato, M, 1987) |
| "A prospective randomized double-blind trial comparing the butyrophenone analogue domperidone (D) and the synthetic cannabinoid nabilone (N) in the treatment of cytotoxic-induced emesis was conducted in 38 patients receiving highly emetogenic chemotherapy regimens (70% containing cisplatin)." | 9.06 | Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis. ( Fennelly, JJ; Pomeroy, M; Towers, M, 1986) |
| "A randomized double-blind cross-over study was performed to evaluate the possible anti-emetic effect of the partial opiate antagonist buprenorphine in comparison to domperidone in chemotherapy-induced nausea and vomiting." | 9.06 | Buprenorphine versus domperidone in chemotherapy-induced emesis: a pilot study. ( Dullemond-Westland, AC; Neijt, JP; Nortier, JW; Sitsen, JM, 1986) |
| "The anti-emetic effects of domperidone were evaluated under double-blind conditions in twenty-four patients with acute vomiting randomly assigned to treatment either with 10 mg i." | 9.05 | Double-blind evaluation of domperidone in acute vomiting and dyspeptic disorders. ( Agorastos, I; Goulis, G; Kaprinis, I; Zissis, NP, 1981) |
| "In a double-blind comparison of domperidone 10 mg, domperidone 4 mg, metoclopramide 10 mg and a placebo, 176 adult patients were given an intravenous injection of one of these substances after postoperative vomiting had occurred." | 9.05 | Postoperative vomiting treated with domperidone. A double-blind comparison with metoclopramide and a placebo. ( Boghaert, A; Carron, D; Gallant, J; Stockman, A, 1980) |
| "In a single-blind trial of therapy in 20 patients with idiopathic Parkinson disease, domperidone prevented nausea and vomiting induced by bromocriptine without diminishing beneficial central effects." | 9.05 | Bromocriptine and domperidone in the treatment of Parkinson disease. ( Agid, Y; Illas, A; Lhermitte, F; Quinn, N, 1981) |
| " We wanted to study the effects of the new antiemetic Domperidone on vomiting after either anesthesia." | 9.05 | [Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)]. ( Alon, E; Axhausen, C; Bernoulli, L; Caluori, R; Hossli, G, 1982) |
| "There is increased awareness about risks and benefits of using domperidone to treat gastroparesis." | 7.83 | Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016) |
| "A retrospective chart review was conducted of patients with nausea (N) and vomiting (V) receiving domperidone from 2009 to 2013 under an Investigational New Drug (IND) protocol." | 7.81 | Cardiovascular safety profile and clinical experience with high-dose domperidone therapy for nausea and vomiting. ( Alvarez, A; Cooper, CJ; Gomez, Y; McCallum, RW; Ortiz, A; Sarosiek, I, 2015) |
| "To retrospectively analyze the individual risk factors for radioactive iodine (RAI)-associated nausea and vomiting, and to examine the anti-emetic effect of ramosetron (5-hydroxytryptamine-3 receptor antagonist) in RAI therapy." | 7.80 | Moderate to severe nausea in radioactive iodine (RAI) therapy is associated with the RAI dose per body weight and was not prevented by ramosetron. ( Ando, T; Ikeoka, T; Imaizumi, M; Kawakami, A; Ueki, I; Usa, T, 2014) |
| ") on spontaneous behaviour and the emesis and behavioural change induced by apomorphine (0." | 7.73 | Differential action of domperidone to modify emesis and behaviour induced by apomorphine in the ferret. ( Lau, AH; Ngan, MP; Rudd, JA; Yew, DT, 2005) |
| " In the present studies, therefore, we used Suncus murinus, a species of insectivore capable of emesis, to investigate if the vanilloid receptor agonist resiniferatoxin is capable of modeling the emesis associated with migraine." | 7.73 | Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew). ( Andrews, PL; Cheng, FH; Moreaux, B; Ngan, MP; Rudd, JA; Sam, TS; Wai, MK; Wan, C, 2005) |
| "Our aim was to determine whether domperidone could improve the symptoms of patients with gastroparesis, accelerate gastric emptying, and enhance quality of life." | 7.69 | The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis. ( McCallum, RW; Sarosiek, I; Soykan, I, 1997) |
| "Loperamide, an opiate receptor agonist, commonly used in the treatment of diarrhoea, reliably induced emesis in the ferret, when given subcutaneously." | 7.68 | The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors. ( Andrews, PL; Bhandari, P; Bingham, S, 1992) |
| "Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone." | 7.68 | The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting. ( Lencz, L, 1990) |
| " We designed a comparative controlled study of Sulpiride and Domperidone, against nausea and vomiting during cancer chemotherapy." | 7.67 | [Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986) |
| "Having noticed psychotic traits in some patients showing incoercible vomiting due to antineoplastic drugs we have thought of establishing a therapy with lithium in the days preceding the therapeutic cycle in order to reduce the emetic events." | 7.67 | Sequential therapy with lithium in chemotherapy-induced vomiting. ( Alfano, G; Candido, A; Mango, G; Menichella, G; Rossi, P; Tartaglione, R, 1985) |
| "Domperidone was not effective for the symptomatic treatment of vomiting during acute gastroenteritis." | 6.82 | Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial. ( Arrighini, A; Barbi, E; Bertolani, P; Biban, P; Bonati, M; Clavenna, A; Da Dalt, L; Guala, A; Maestro, A; Marchetti, F; Mazzoni, E; Pazzaglia, A; Perri, PF; Reale, A; Renna, S; Ronfani, L; Rovere, F; Urbino, AF; Valletta, E; Vitale, A; Zangardi, T; Zanon, D, 2016) |
| "Cisapride was previously used in the same indication." | 6.74 | Domperidone versus cisapride in the treatment of infant regurgitation and increased acid gastro-oesophageal reflux: a pilot study. ( Advani, N; Alatas, S; Firmansyah, A; Hegar, B; Vandenplas, Y, 2009) |
| "At the end of the treatment period, nausea, vomiting and reflux symptoms, adverse events and a global assessment of patients' symptom control were recorded by the investigator." | 6.67 | A comparison of controlled release metoclopramide and domperidone in the treatment of nausea and vomiting. ( Miller, AJ; Patel, NH; Roy, P, 1991) |
| "Droperidol was significantly more effective than domperidone, metoclopramide or placebo in reducing emetic sequelae." | 6.66 | Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery. ( Madej, TH; Simpson, KH, 1986) |
| " High-dose metoclopramide has demonstrated efficacy in small series of patients in the treatment of cisplatin-induced vomiting." | 6.15 | Advances in anti-emetic therapy. ( Bakowski, MT, 1984) |
| "Domperidone is a commonly prescribed antiemetic drug but its side effects are rarely seen." | 5.40 | Domperidone-induced dystonia: a rare and troublesome complication. ( Bhandari, D; Dhakal, M; Dhakal, OP, 2014) |
| "In this randomized, double-blind, phase 3 study, children ages 6 months to 12 years with acute gastroenteritis randomly (1:1) received oral domperidone 0." | 5.30 | Safety and Efficacy of Low-dose Domperidone for Treating Nausea and Vomiting Due to Acute Gastroenteritis in Children. ( Appiani, C; Garces-Sanchez, M; Gupta, R; Hu, P; Leitz, G; Li, Q; Mitha, E, 2019) |
| "Pretreatment with domperidone inhibited apomorphine-induced kaolin intake." | 5.29 | Pica in rats is analogous to emesis: an animal model in emesis research. ( Hasegawa, S; Matsunaga, T; Morita, M; Takeda, N, 1993) |
| "Apomorphine induced an increase of gastrin levels which peaked at 5 min." | 5.27 | Effects of dopamine receptor antagonists on gastrin and vomiting responses to apomorphine. ( Goiny, M; Uvnäs-Moberg, K, 1987) |
| "Domperidone is an antiemetic that is often prescribed for children with acute gastroenteritis in Japan." | 5.20 | Domperidone with ORT in the treatment of pediatric acute gastroenteritis in Japan: a multicenter, randomized controlled trial. ( Hinotsu, S; Kawakami, K; Kishida, K; Kita, F; Nakahata, T; Sasaki, H; Shimakawa, T; Urushihara, H; Wakazono, Y; Yamauchi, E; Yorifuji, T, 2015) |
| "To compare the efficacy of ondansetron and domperidone for the symptomatic treatment of vomiting in children with AG who have failed ORT." | 5.15 | Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial. ( Arrighini, A; Bertolani, P; Biban, P; Bonati, M; Clavenna, A; Da Dalt, L; Di Pietro, P; Guala, A; Maestro, A; Mannelli, F; Marchetti, F; Messi, G; Pazzaglia, A; Perri, F; Reale, A; Renna, S; Ronfani, L; Rovere, F; Tondelli, MT; Urbino, AF; Valletta, E; Vitale, A; Zangardi, T; Zanon, D, 2011) |
| " During 5 days prior to the apomorphine all received Motilium (domperidone, 60 mg/d) to prevent nausea and vomiting." | 5.09 | [Apomorphine for treatment of "off-periods" in Parkinson's disease]. ( Kuritzky, A; Melamed, E; Merims, D; Ziv, I; Zoldan, J, 1999) |
| "To compare ondansetron and domperidone for treatment of delayed nausea/vomiting (DN/V) following highly emetogenic chemotherapy, after attaining total suppression of emesis on the day of chemotherapy by mean of ondansetron (combined with dexamethasone in the case of cisplatin-treated patients)." | 5.08 | Prophylaxis of delayed nausea and vomiting after cancer chemotherapy. ( Borm, JJ; Esseboom, EU; Rojer, RA; Statius van Eps, LW, 1995) |
| "We investigated the usefulness of concurrent therapy of granisetron with methylprednisolone sodium for on nausea, vomiting and anorexia induced by chemotherapy, including cisplatin, in patients with oral cancer." | 5.07 | [Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin]. ( Kawashima, T; Miyata, K; Morita, N; Ohmata, T; Sakamoto, T; Wada, T, 1993) |
| "A prospective randomized double-blind trial comparing the butyrophenone analogue domperidone (D) and the synthetic cannabinoid nabilone (N) in the treatment of cytotoxic-induced emesis was conducted in 38 patients receiving highly emetogenic chemotherapy regimens (70% containing cisplatin)." | 5.06 | Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis. ( Fennelly, JJ; Pomeroy, M; Towers, M, 1986) |
| " CMF were included in a double-blind comparative study aimed at evaluating the efficacy of 3 different drugs (methylprednisolone (MP), metoclopramide (MTC), and domperidone (DMP) in preventing chemotherapy-induced nausea and vomiting." | 5.06 | Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF. ( Ballatori, E; Basurto, C; del Favero, A; Minotti, V; Roila, F; Tonato, M, 1987) |
| "A randomized double-blind cross-over study was performed to evaluate the possible anti-emetic effect of the partial opiate antagonist buprenorphine in comparison to domperidone in chemotherapy-induced nausea and vomiting." | 5.06 | Buprenorphine versus domperidone in chemotherapy-induced emesis: a pilot study. ( Dullemond-Westland, AC; Neijt, JP; Nortier, JW; Sitsen, JM, 1986) |
| "In a single-blind trial of therapy in 20 patients with idiopathic Parkinson disease, domperidone prevented nausea and vomiting induced by bromocriptine without diminishing beneficial central effects." | 5.05 | Bromocriptine and domperidone in the treatment of Parkinson disease. ( Agid, Y; Illas, A; Lhermitte, F; Quinn, N, 1981) |
| "In a double-blind comparison of domperidone 10 mg, domperidone 4 mg, metoclopramide 10 mg and a placebo, 176 adult patients were given an intravenous injection of one of these substances after postoperative vomiting had occurred." | 5.05 | Postoperative vomiting treated with domperidone. A double-blind comparison with metoclopramide and a placebo. ( Boghaert, A; Carron, D; Gallant, J; Stockman, A, 1980) |
| " Ondansetron revealed the largest effect in comparison to placebo for cessation of vomiting (odds ratio = 0." | 5.05 | Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis. ( Acosta-Reyes, J; Florez, ID; Niño-Serna, LF; Veroniki, AA, 2020) |
| " We wanted to study the effects of the new antiemetic Domperidone on vomiting after either anesthesia." | 5.05 | [Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)]. ( Alon, E; Axhausen, C; Bernoulli, L; Caluori, R; Hossli, G, 1982) |
| "The anti-emetic effects of domperidone were evaluated under double-blind conditions in twenty-four patients with acute vomiting randomly assigned to treatment either with 10 mg i." | 5.05 | Double-blind evaluation of domperidone in acute vomiting and dyspeptic disorders. ( Agorastos, I; Goulis, G; Kaprinis, I; Zissis, NP, 1981) |
| "A search of two bibliographic databases, the European Medicines Agency (EMA) website, Micromedex, Lexicomp and reference texts was undertaken for domperidone related reports of QT prolongation, cardiac arrhythmias and/or SCD." | 4.91 | Domperidone safety: a mini-review of the science of QT prolongation and clinical implications of recent global regulatory recommendations. ( Buffery, PJ; Strother, RM, 2015) |
| "To evaluate the risk of QT prolongation, ventricular arrhythmias and sudden cardiac death associated with the use of oral domperidone in adults without cancer." | 4.91 | [Cardiac adverse effects of domperidone in adult patients: a systematic review]. ( Avila, A; Caraballo, L; Marzi, M; Molina, G; Piskulic, L; Weitz, D, 2015) |
| "In patients with advanced cancer not being treated with chemotherapy or radiation therapy, metoclopramide can be used to reduce nausea and vomiting." | 4.88 | [Treatment of nausea and vomiting with prokinetics and neuroleptics in palliative care patients : a review]. ( Alt-Epping, B; Benze, G; Geyer, A; Nauck, F, 2012) |
| "To review the pharmacology, pharmacokinetics, efficacy, and safety of domperidone in the treatment of gastrointestinal motility disorders and emesis." | 4.80 | Domperidone: a peripherally acting dopamine2-receptor antagonist. ( Barone, JA, 1999) |
| "Risk-minimization measures (RMM), including label revisions were implemented in Europe for domperidone because of evidence of increased incidence of cardiac arrhythmia and sudden cardiac death." | 3.91 | Awareness of, and Compliance with, Domperidone Revised Labeling After a Risk-Minimization Activity in Europe. ( Fife, D; Hu, P; Kaplan, S; Oliveria, SA; Phillips, S; Richarz, U; Waller, J, 2019) |
| "Domperidone is a dopamine antagonist used for the symptomatic management of nausea and vomiting." | 3.91 | Impact of Safety Warning on Domperidone Prescribing for Geriatric Patients in South Korea: Analysis of National Insurance Claim Data. ( Han, N; Oh, JM; Rhew, K, 2019) |
| "There is increased awareness about risks and benefits of using domperidone to treat gastroparesis." | 3.83 | Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort. ( Midani, D; Parkman, HP; Parupalli, R; Roberts, AC; Saadi, M; Schey, R, 2016) |
| "A retrospective chart review was conducted of patients with nausea (N) and vomiting (V) receiving domperidone from 2009 to 2013 under an Investigational New Drug (IND) protocol." | 3.81 | Cardiovascular safety profile and clinical experience with high-dose domperidone therapy for nausea and vomiting. ( Alvarez, A; Cooper, CJ; Gomez, Y; McCallum, RW; Ortiz, A; Sarosiek, I, 2015) |
| "To retrospectively analyze the individual risk factors for radioactive iodine (RAI)-associated nausea and vomiting, and to examine the anti-emetic effect of ramosetron (5-hydroxytryptamine-3 receptor antagonist) in RAI therapy." | 3.80 | Moderate to severe nausea in radioactive iodine (RAI) therapy is associated with the RAI dose per body weight and was not prevented by ramosetron. ( Ando, T; Ikeoka, T; Imaizumi, M; Kawakami, A; Ueki, I; Usa, T, 2014) |
| "Domperidone is a dopamine antagonist that has recently been released in Canada." | 3.76 | Domperidone, a new dopamine antagonist. ( Champion, MC; Hartnett, M; Yen, M, 1986) |
| " We performed retrospective study that examined the efficacy of preventive treatment (granisetron+dexamethasone+domperidone) for delayed emesis induced by FOLFOX4 chemotherapy for advanced and recurrent colorectal cancer." | 3.75 | [Efficacy of preventive treatment for delayed emesis induced by FOLFOX4 chemotherapy]. ( Hama, T; Hatake, K; Imada, H; Kamisugi, K; Kawakami, K; Matsusaka, S; Mizunuma, N; Nakamoto, E; Shinozaki, E; Shirai, T; Shouji, D; Suenaga, M; Suzuki, W; Takahashi, G; Yokokawa, T, 2009) |
| " In the present studies, therefore, we used Suncus murinus, a species of insectivore capable of emesis, to investigate if the vanilloid receptor agonist resiniferatoxin is capable of modeling the emesis associated with migraine." | 3.73 | Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew). ( Andrews, PL; Cheng, FH; Moreaux, B; Ngan, MP; Rudd, JA; Sam, TS; Wai, MK; Wan, C, 2005) |
| ") on spontaneous behaviour and the emesis and behavioural change induced by apomorphine (0." | 3.73 | Differential action of domperidone to modify emesis and behaviour induced by apomorphine in the ferret. ( Lau, AH; Ngan, MP; Rudd, JA; Yew, DT, 2005) |
| "Antiemetic effect and safety of concurrent administration of ondansetron and other antiemetics (dexamethasone, domperidone and ethyl loflazepate), given for complete suppression of nausea/vomiting, were examined in 46 patients (109 courses) with gynecological cancer receiving single high-dose of cisplatin or carboplatin." | 3.69 | [Multi-drug antiemetic treatment and effect of treatment duration of concurrent steroids--for complete control of chemotherapy-induced nausea/vomiting in gynecological cancer]. ( Fujii, T; Kioka, H; Naito, H; Nakata, N; Sawasaki, T; Shigemasa, K; Shiroyama, Y; Tanimoto, H, 1997) |
| "Our aim was to determine whether domperidone could improve the symptoms of patients with gastroparesis, accelerate gastric emptying, and enhance quality of life." | 3.69 | The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis. ( McCallum, RW; Sarosiek, I; Soykan, I, 1997) |
| "Loperamide, an opiate receptor agonist, commonly used in the treatment of diarrhoea, reliably induced emesis in the ferret, when given subcutaneously." | 3.68 | The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors. ( Andrews, PL; Bhandari, P; Bingham, S, 1992) |
| "Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone." | 3.68 | The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting. ( Lencz, L, 1990) |
| "Intramuscular injection of xylazine induced dose-dependent vomiting in cats (ED50 = 0." | 3.67 | Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats. ( Hikasa, Y; Ogasawara, S; Takase, K, 1989) |
| "The incidence of dyspepsias and emesis occurring either as accompanying symptoms of gynaecological operations or as independent clinical conditions, therapeutic means for controlling these conditions and the mechanism of action and clinical usefulness of the dopamine antagonist domperidone have been discussed." | 3.67 | Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting. ( Sásdi, A, 1989) |
| " We designed a comparative controlled study of Sulpiride and Domperidone, against nausea and vomiting during cancer chemotherapy." | 3.67 | [Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method]. ( Kawakami, K; Kawatsu, S; Komatsu, Y; Okamoto, K; Sakata, Y; Satoh, T; Suzuki, H; Takagi, S; Tanabe, K; Yoshida, Y, 1986) |
| "A dose-finding multicenter study was undertaken to evaluate the antiemetic efficacy of domperidone, an antidopaminergic drug, which has been proposed as a suitable alternative to high-dose metoclopramide in the control of cisplatin-induced nausea and vomiting." | 3.67 | A pilot study of high-dose domperidone as an antiemetic in patients treated with cisplatin. ( del Favero, A; Franzosi, MG; Pampallona, S; Roila, F; Tognoni, G; Tonato, M, 1985) |
| "Having noticed psychotic traits in some patients showing incoercible vomiting due to antineoplastic drugs we have thought of establishing a therapy with lithium in the days preceding the therapeutic cycle in order to reduce the emetic events." | 3.67 | Sequential therapy with lithium in chemotherapy-induced vomiting. ( Alfano, G; Candido, A; Mango, G; Menichella, G; Rossi, P; Tartaglione, R, 1985) |
| "The antiemetic effect of domperidone against nausea, vomiting, and anorexia induced by antineoplastic agents was compared with that of chlorpromazine." | 3.66 | [Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine]. ( Araki, Y; Seita, M; Tamura, K, 1983) |
| "Domperidone is a peripheral dopamine-2 receptor antagonist with prokinetic and antiemetic properties." | 3.01 | Drugs in Focus: Domperidone. ( Assa, A; Benninga, M; Borrelli, O; Broekaert, IJ; Carpi, FJM; Deganello Saccomani, M; Dolinsek, J; Homan, M; Mas, E; Miele, E; Puoti, MG; Thomson, M; Tzivinikos, C, 2023) |
| "Domperidone was not effective for the symptomatic treatment of vomiting during acute gastroenteritis." | 2.82 | Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial. ( Arrighini, A; Barbi, E; Bertolani, P; Biban, P; Bonati, M; Clavenna, A; Da Dalt, L; Guala, A; Maestro, A; Marchetti, F; Mazzoni, E; Pazzaglia, A; Perri, PF; Reale, A; Renna, S; Ronfani, L; Rovere, F; Urbino, AF; Valletta, E; Vitale, A; Zangardi, T; Zanon, D, 2016) |
| "A recently developed oral serotonergic challenge test consisting of 5-Hydroxytryptophane (5-HTP, 200 mg) combined with carbidopa (CBD, 100 mg + 50 mg) exhibited dose-related neuroendocrine responsiveness and predictable pharmacokinetics." | 2.75 | Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron. ( de Kam, ML; Derijk, RH; Jacobs, GE; Kamerling, IM; van Gerven, JM; van Pelt, J; Zitman, FG, 2010) |
| "Cisapride was previously used in the same indication." | 2.74 | Domperidone versus cisapride in the treatment of infant regurgitation and increased acid gastro-oesophageal reflux: a pilot study. ( Advani, N; Alatas, S; Firmansyah, A; Hegar, B; Vandenplas, Y, 2009) |
| "At the end of the treatment period, nausea, vomiting and reflux symptoms, adverse events and a global assessment of patients' symptom control were recorded by the investigator." | 2.67 | A comparison of controlled release metoclopramide and domperidone in the treatment of nausea and vomiting. ( Miller, AJ; Patel, NH; Roy, P, 1991) |
| "Droperidol was significantly more effective than domperidone, metoclopramide or placebo in reducing emetic sequelae." | 2.66 | Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery. ( Madej, TH; Simpson, KH, 1986) |
| "Functional vomiting is rare and presents with more frequent vomiting episodes." | 2.44 | Functional nausea and vomiting. ( Talley, NJ, 2007) |
| "Domperidone is a dopamine-2 receptor antagonist." | 2.44 | Domperidone: review of pharmacology and clinical applications in gastroenterology. ( McCallum, RW; Reddymasu, SC; Soykan, I, 2007) |
| "Nausea and vomiting are common symptoms of migraine, which can be controlled with a variety of anti-emetics including phenothiazines and antihistamines." | 2.41 | Anti-emetics. ( MacGregor, EA, 2001) |
| "Domperidone is a commonly prescribed antiemetic drug but its side effects are rarely seen." | 1.40 | Domperidone-induced dystonia: a rare and troublesome complication. ( Bhandari, D; Dhakal, M; Dhakal, OP, 2014) |
| "Antiemetics are not included for treatment of vomiting associated with acute gastroenteritis (AGE) in children by standard guidelines." | 1.33 | Antiemetics for children with gastroenteritis: off-label but still on in clinical practice. ( Albano, F; Bruzzese, E; De Marco, G; Spagnuolo, MI, 2006) |
| " A next group of 87 patients received 60 mg/kg nicotinamide in combination with domperidone." | 1.31 | Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy. ( Bussink, J; Folkes, LK; Kaanders, JH; Stratford, MR; van der Kogel, AJ, 2002) |
| "Domperidone did not inhibit these cytotoxic agents-induced emeses." | 1.29 | The effects of orally administered Y-25130, a selective serotonin3-receptor antagonist, on chemotherapeutic agent-induced emesis. ( Fukuda, T; Haga, K; Inaba, K; Morimoto, Y; Setoguchi, M; Shoji, H, 1993) |
| "Pretreatment with domperidone inhibited apomorphine-induced kaolin intake." | 1.29 | Pica in rats is analogous to emesis: an animal model in emesis research. ( Hasegawa, S; Matsunaga, T; Morita, M; Takeda, N, 1993) |
| "Vomiting was secondary to an obstruction in the antrum of the stomach caused by a mass consisting of alginate." | 1.27 | Increased vomiting induced by an antiemetic drug. ( Degenhart, HJ; den Ouden, WJ; Luyendijk, I; Sinaasappel, M, 1984) |
| "Domperidone is an effective antiemetic for children receiving cytotoxic therapy." | 1.27 | Continuous ECG monitoring of children with cancer receiving domperidone. ( Campbell, RW; Craft, AW; Hunter, AS; Nobbs, J; Pritchard-Jones, K; Ratcliffe, JM, 1986) |
| "The emetic and catalepsy-inducing actions of buflomedil were studied in dog and mice." | 1.27 | [Emetic and catalepsy-inducing actions of buflomedil]. ( Hashimoto, T; Koda, H; Kuriyama, K, 1988) |
| "Domperidone pretreatment prevented radiation-induced emesis in all of four dogs tested." | 1.27 | Radiation-induced emesis in the dog: effects of lesions and drugs. ( Briggs, DB; Carpenter, DO; Knox, AP; Strominger, NL, 1986) |
| "Apomorphine was about 30 times more potent in inducing gastric relaxation when applied intracerebroventricularly (i." | 1.27 | Influence of peripheral and central administration of apomorphine and morphine on intragastric pressure in the dog. ( Blancquaert, JP; Lefebvre, RA; Willems, JL, 1985) |
| "Domperidone was given twice a day for one week." | 1.27 | [Effect of combined use of adrenocortical hormones and domperidone as anti-emetics during cisplatin therapy]. ( Hirose, Y; Matsushita, T; Mise, K; Nakanishi, M; Shirosaki, H; Tanaka, T; Yamaoto, T, 1985) |
| "Apomorphine induced an increase of gastrin levels which peaked at 5 min." | 1.27 | Effects of dopamine receptor antagonists on gastrin and vomiting responses to apomorphine. ( Goiny, M; Uvnäs-Moberg, K, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 82 (57.75) | 18.7374 |
| 1990's | 19 (13.38) | 18.2507 |
| 2000's | 12 (8.45) | 29.6817 |
| 2010's | 26 (18.31) | 24.3611 |
| 2020's | 3 (2.11) | 2.80 |
| Authors | Studies |
|---|---|
| Puoti, MG | 1 |
| Assa, A | 1 |
| Benninga, M | 1 |
| Broekaert, IJ | 1 |
| Carpi, FJM | 1 |
| Deganello Saccomani, M | 1 |
| Dolinsek, J | 1 |
| Homan, M | 1 |
| Mas, E | 1 |
| Miele, E | 1 |
| Tzivinikos, C | 1 |
| Thomson, M | 1 |
| Borrelli, O | 1 |
| Rhew, K | 1 |
| Han, N | 1 |
| Oh, JM | 1 |
| Niño-Serna, LF | 1 |
| Acosta-Reyes, J | 1 |
| Veroniki, AA | 1 |
| Florez, ID | 1 |
| Yan, XJ | 1 |
| Xu, P | 1 |
| Qiu, HY | 1 |
| Wang, B | 2 |
| Luo, QQ | 1 |
| Chen, SL | 1 |
| Giusti, R | 1 |
| Mazzotta, M | 1 |
| Filetti, M | 1 |
| Daniele, G | 1 |
| Tsukuura, H | 2 |
| Ficorella, C | 1 |
| Porzio, G | 1 |
| Marchetti, P | 1 |
| Verna, L | 1 |
| Leitz, G | 1 |
| Hu, P | 2 |
| Appiani, C | 1 |
| Li, Q | 1 |
| Mitha, E | 1 |
| Garces-Sanchez, M | 1 |
| Gupta, R | 1 |
| Di Lorenzo, C | 1 |
| Nurko, S | 1 |
| Fife, D | 1 |
| Waller, J | 1 |
| Kaplan, S | 1 |
| Phillips, S | 1 |
| Oliveria, SA | 1 |
| Richarz, U | 1 |
| Ikeoka, T | 1 |
| Ando, T | 1 |
| Imaizumi, M | 1 |
| Ueki, I | 1 |
| Usa, T | 1 |
| Kawakami, A | 1 |
| Ramos, L | 1 |
| Alarcón, O | 1 |
| Adrian, Z | 1 |
| Gimeno-García, AZ | 1 |
| Nicolás-Pérez, D | 1 |
| Jiménez-Sosa, A | 1 |
| Quintero, E | 1 |
| Dhakal, OP | 1 |
| Dhakal, M | 1 |
| Bhandari, D | 1 |
| Zhang, XF | 1 |
| Yin, GZ | 1 |
| Liu, QG | 1 |
| Liu, XM | 1 |
| Yu, L | 1 |
| Liu, SN | 1 |
| Cui, HY | 1 |
| Lv, Y | 1 |
| Furyk, JS | 1 |
| Meek, R | 1 |
| McKenzie, S | 1 |
| Ortiz, A | 1 |
| Cooper, CJ | 1 |
| Alvarez, A | 1 |
| Gomez, Y | 1 |
| Sarosiek, I | 2 |
| McCallum, RW | 4 |
| Marzi, M | 1 |
| Weitz, D | 1 |
| Avila, A | 1 |
| Molina, G | 1 |
| Caraballo, L | 1 |
| Piskulic, L | 1 |
| Buffery, PJ | 1 |
| Strother, RM | 1 |
| Ando, Y | 1 |
| Gyawali, B | 1 |
| Matsumoto, M | 1 |
| Sugishita, M | 1 |
| Honda, K | 1 |
| Urakawa, H | 1 |
| Maeda, O | 1 |
| Hasegawa, Y | 1 |
| Smith, LA | 1 |
| Azariah, F | 1 |
| Lavender, VT | 1 |
| Stoner, NS | 1 |
| Bettiol, S | 1 |
| Lewis, K | 1 |
| Alqahtani, Z | 1 |
| Mcintyre, L | 1 |
| Almenawer, S | 1 |
| Alshamsi, F | 1 |
| Rhodes, A | 1 |
| Evans, L | 1 |
| Angus, DC | 1 |
| Alhazzani, W | 1 |
| Schey, R | 1 |
| Saadi, M | 1 |
| Midani, D | 1 |
| Roberts, AC | 1 |
| Parupalli, R | 1 |
| Parkman, HP | 1 |
| Marchetti, F | 2 |
| Bonati, M | 2 |
| Maestro, A | 2 |
| Zanon, D | 2 |
| Rovere, F | 2 |
| Arrighini, A | 2 |
| Barbi, E | 1 |
| Bertolani, P | 2 |
| Biban, P | 2 |
| Da Dalt, L | 2 |
| Guala, A | 2 |
| Mazzoni, E | 1 |
| Pazzaglia, A | 2 |
| Perri, PF | 1 |
| Reale, A | 2 |
| Renna, S | 2 |
| Urbino, AF | 2 |
| Valletta, E | 2 |
| Vitale, A | 2 |
| Zangardi, T | 2 |
| Clavenna, A | 2 |
| Ronfani, L | 2 |
| Jacobs, GE | 1 |
| Kamerling, IM | 1 |
| de Kam, ML | 1 |
| Derijk, RH | 1 |
| van Pelt, J | 1 |
| Zitman, FG | 1 |
| van Gerven, JM | 1 |
| Hegar, B | 1 |
| Alatas, S | 1 |
| Advani, N | 1 |
| Firmansyah, A | 1 |
| Vandenplas, Y | 1 |
| Yokokawa, T | 1 |
| Matsusaka, S | 1 |
| Shouji, D | 1 |
| Imada, H | 1 |
| Nakamoto, E | 1 |
| Kamisugi, K | 1 |
| Suzuki, W | 1 |
| Shirai, T | 1 |
| Takahashi, G | 1 |
| Kawakami, K | 3 |
| Shinozaki, E | 1 |
| Suenaga, M | 1 |
| Mizunuma, N | 1 |
| Hatake, K | 1 |
| Hama, T | 1 |
| Di Pietro, P | 1 |
| Mannelli, F | 1 |
| Messi, G | 1 |
| Perri, F | 1 |
| Tondelli, MT | 1 |
| Festin, M | 1 |
| Kita, F | 1 |
| Hinotsu, S | 1 |
| Yorifuji, T | 1 |
| Urushihara, H | 1 |
| Shimakawa, T | 1 |
| Kishida, K | 1 |
| Wakazono, Y | 1 |
| Yamauchi, E | 1 |
| Sasaki, H | 1 |
| Nakahata, T | 1 |
| Pinto, TF | 1 |
| Rocha, R | 1 |
| Paula, CA | 1 |
| de Jesus, RP | 1 |
| Pozzi, M | 1 |
| Strazzer, S | 1 |
| Locatelli, F | 1 |
| Galbiati, S | 1 |
| Formica, F | 1 |
| Maestri, L | 1 |
| Clementi, E | 1 |
| Radice, S | 1 |
| Scott, B | 1 |
| Benze, G | 1 |
| Alt-Epping, B | 1 |
| Geyer, A | 1 |
| Nauck, F | 1 |
| Segula, D | 1 |
| Mwandiambira, V | 1 |
| Howson, W | 1 |
| Allain, TJ | 1 |
| Bussink, J | 1 |
| Stratford, MR | 1 |
| van der Kogel, AJ | 1 |
| Folkes, LK | 1 |
| Kaanders, JH | 1 |
| MacGregor, EA | 1 |
| Cheng, FH | 1 |
| Andrews, PL | 2 |
| Moreaux, B | 1 |
| Ngan, MP | 2 |
| Rudd, JA | 2 |
| Sam, TS | 1 |
| Wai, MK | 1 |
| Wan, C | 1 |
| Lau, AH | 1 |
| Yew, DT | 1 |
| Albano, F | 1 |
| Bruzzese, E | 1 |
| Spagnuolo, MI | 1 |
| De Marco, G | 1 |
| Reddymasu, SC | 1 |
| Soykan, I | 2 |
| Talley, NJ | 1 |
| Robinson, P | 1 |
| Bakowski, MT | 1 |
| Joss, RA | 1 |
| Goldhirsch, A | 1 |
| Brunner, KW | 1 |
| Galeazzi, RL | 1 |
| van der Steen, M | 1 |
| Du Caju, MV | 1 |
| Van Acker, KJ | 1 |
| Casteels-Van Daele, M | 1 |
| Dobosz-Cyklis, R | 1 |
| Van de Casseye, W | 1 |
| Verbeeck, P | 1 |
| Wijndaele, L | 1 |
| Palazzo, MG | 1 |
| Strunin, L | 1 |
| Giaccone, G | 1 |
| Bertetto, O | 1 |
| Calciati, A | 1 |
| Di Paolo, N | 1 |
| De Mia, M | 1 |
| Gaggiotti, E | 1 |
| Baggerman, C | 1 |
| Sinaasappel, M | 1 |
| den Ouden, WJ | 1 |
| Luyendijk, I | 1 |
| Degenhart, HJ | 1 |
| Guldager, H | 1 |
| Jensen, FM | 1 |
| Andersen, KH | 1 |
| Arnfred, I | 1 |
| Clarke, RS | 1 |
| Dubois, A | 2 |
| Jacobus, JP | 1 |
| Grissom, MP | 1 |
| Eng, RR | 2 |
| Conklin, JJ | 2 |
| Spelina, KR | 1 |
| Gerber, HR | 1 |
| Pagels, IL | 1 |
| Valenzuela, JE | 1 |
| Dooley, CP | 1 |
| Weaving, A | 1 |
| Bezwoda, WR | 1 |
| Derman, DP | 1 |
| Roussak, JB | 1 |
| Carey, P | 1 |
| Parry, H | 1 |
| Usui, N | 1 |
| Ogawa, K | 1 |
| Inagaki, J | 1 |
| Horikoshi, N | 1 |
| Inoue, T | 1 |
| Urabe, A | 1 |
| Saito, T | 2 |
| Takaku, F | 1 |
| Araki, Y | 1 |
| Tamura, K | 1 |
| Seita, M | 1 |
| Warde, P | 1 |
| Cantwell, B | 1 |
| Fennelly, J | 1 |
| Powderly, W | 1 |
| Conroy, R | 1 |
| Ise, T | 1 |
| Ohira, M | 1 |
| Omiya, A | 1 |
| Hirose, M | 1 |
| Shibata, T | 1 |
| Boghaert, A | 1 |
| Carron, D | 1 |
| Gallant, J | 1 |
| Stockman, A | 1 |
| van Leeuwen, L | 2 |
| Helmers, JH | 2 |
| Agorastos, I | 1 |
| Zissis, NP | 1 |
| Kaprinis, I | 1 |
| Goulis, G | 1 |
| Caruso, U | 1 |
| D'Iddio, S | 1 |
| Cravotto, E | 1 |
| Pesce, S | 1 |
| Betti, I | 1 |
| Ruscitto, G | 1 |
| Ecari, U | 1 |
| Sabrie, AM | 1 |
| Minobe, T | 1 |
| Sekine, H | 1 |
| Torii, T | 1 |
| Fujiya, T | 1 |
| Ohtomo, Y | 1 |
| Alon, E | 1 |
| Caluori, R | 1 |
| Bernoulli, L | 1 |
| Axhausen, C | 1 |
| Hossli, G | 1 |
| Tauber, A | 1 |
| Eschar, J | 1 |
| Labatto, S | 1 |
| van den Broek, PJ | 1 |
| Henny, FC | 1 |
| van Dijk, JG | 1 |
| Bogaert, M | 1 |
| Quinn, N | 1 |
| Illas, A | 1 |
| Lhermitte, F | 1 |
| Agid, Y | 1 |
| Gnauen, H | 1 |
| Esseboom, EU | 1 |
| Rojer, RA | 1 |
| Borm, JJ | 1 |
| Statius van Eps, LW | 1 |
| Olver, IN | 1 |
| Laidlaw, CR | 1 |
| Matthews, JP | 1 |
| Bishop, JF | 1 |
| Hayes, AM | 1 |
| Wolf, M | 1 |
| Toner, GC | 1 |
| Haga, K | 1 |
| Inaba, K | 1 |
| Shoji, H | 1 |
| Morimoto, Y | 1 |
| Fukuda, T | 1 |
| Setoguchi, M | 1 |
| Kawashima, T | 1 |
| Wada, T | 1 |
| Morita, N | 1 |
| Ohmata, T | 1 |
| Miyata, K | 1 |
| Sakamoto, T | 1 |
| Carella, G | 1 |
| Marra, L | 1 |
| Takeda, N | 1 |
| Hasegawa, S | 1 |
| Morita, M | 1 |
| Matsunaga, T | 1 |
| Iwanaga, Y | 1 |
| Miyashita, N | 1 |
| Morikawa, K | 1 |
| Itoh, Z | 1 |
| Rampello, L | 1 |
| Raffaele, R | 1 |
| Nicoletti, G | 1 |
| Le Pira, F | 1 |
| Vecchio, I | 1 |
| Malaguarnera, M | 1 |
| Drago, F | 1 |
| Fujii, T | 1 |
| Nakata, N | 1 |
| Shiroyama, Y | 1 |
| Sawasaki, T | 1 |
| Tanimoto, H | 1 |
| Shigemasa, K | 1 |
| Kioka, H | 1 |
| Naito, H | 1 |
| Barone, JA | 1 |
| Zoldan, J | 1 |
| Merims, D | 1 |
| Kuritzky, A | 1 |
| Ziv, I | 1 |
| Melamed, E | 1 |
| Lefebvre, RA | 2 |
| Willems, JL | 2 |
| Bhandari, P | 1 |
| Bingham, S | 1 |
| Polubiec, A | 1 |
| Krasnopolska-Polanczky, Z | 1 |
| Duda-Król, W | 1 |
| Jórasz, I | 1 |
| Witkowski, J | 1 |
| Varga, A | 1 |
| Lovas, J | 1 |
| Roy, P | 1 |
| Patel, NH | 1 |
| Miller, AJ | 1 |
| Bonuccelli, U | 1 |
| Nocchiero, A | 1 |
| Napolitano, A | 1 |
| Paoletti, AM | 1 |
| Melis, GB | 1 |
| Corsini, GU | 1 |
| Muratorio, A | 1 |
| Lencz, L | 1 |
| Williams, CJ | 1 |
| Davies, C | 1 |
| Raval, M | 1 |
| Middleton, J | 1 |
| Luken, J | 1 |
| Stone, B | 1 |
| Lang, IM | 1 |
| Marvig, J | 1 |
| Hikasa, Y | 1 |
| Takase, K | 1 |
| Ogasawara, S | 1 |
| Sásdi, A | 1 |
| Cherian, S | 1 |
| Sachdev, HP | 1 |
| Puri, RK | 1 |
| Dodds, LJ | 1 |
| Osborne, RJ | 1 |
| Slevin, ML | 1 |
| Hunter, RW | 1 |
| Hamer, J | 1 |
| Goiny, M | 1 |
| Uvnäs-Moberg, K | 1 |
| Madej, TH | 2 |
| Simpson, KH | 2 |
| Murakami, M | 1 |
| Ota, K | 1 |
| Dalzell, AM | 1 |
| Bartlett, H | 1 |
| Lilleyman, JS | 1 |
| Pomeroy, M | 1 |
| Fennelly, JJ | 1 |
| Towers, M | 1 |
| Champion, MC | 2 |
| Ratcliffe, JM | 1 |
| Nobbs, J | 1 |
| Campbell, RW | 1 |
| Hunter, AS | 1 |
| Pritchard-Jones, K | 1 |
| Craft, AW | 1 |
| Danquechin Dorval, E | 1 |
| Mueller, GP | 1 |
| Durakovic, A | 1 |
| Carpenter, DO | 2 |
| Briggs, DB | 2 |
| Strominger, NL | 2 |
| Fister, T | 1 |
| Wilson, S | 1 |
| Takács, G | 1 |
| Porkoláb, E | 1 |
| Koda, H | 1 |
| Hashimoto, T | 1 |
| Kuriyama, K | 1 |
| Udvardi, G | 1 |
| Roila, F | 2 |
| Tonato, M | 2 |
| Basurto, C | 1 |
| Minotti, V | 1 |
| Ballatori, E | 1 |
| del Favero, A | 2 |
| Miner, WD | 1 |
| Sanger, GJ | 1 |
| Turner, DH | 1 |
| Fabri, M | 1 |
| Nazzicone, Q | 1 |
| Galanti, A | 1 |
| Maselli, G | 1 |
| King, GL | 1 |
| Horváth, I | 1 |
| Dullemond-Westland, AC | 1 |
| Neijt, JP | 1 |
| Nortier, JW | 1 |
| Sitsen, JM | 1 |
| Hartnett, M | 1 |
| Yen, M | 1 |
| Nappi, C | 1 |
| Colace, G | 1 |
| Di Renzo, GF | 1 |
| Taglialatela, M | 1 |
| Amoroso, S | 1 |
| Annunziato, L | 1 |
| Montemagno, U | 1 |
| Cordts, RE | 1 |
| Yochmowitz, MG | 1 |
| Hardy, KA | 1 |
| Shafrir, Y | 1 |
| Levy, Y | 1 |
| Steinherz, R | 1 |
| Sakata, Y | 1 |
| Suzuki, H | 1 |
| Satoh, T | 1 |
| Kawatsu, S | 1 |
| Tanabe, K | 1 |
| Okamoto, K | 1 |
| Takagi, S | 1 |
| Komatsu, Y | 1 |
| Yoshida, Y | 1 |
| Knox, AP | 1 |
| Biasini, A | 1 |
| Alberti, A | 1 |
| Waldmann, CS | 1 |
| Verghese, C | 1 |
| Short, SM | 1 |
| Goldhill, DR | 1 |
| Evans, SJ | 1 |
| Huys, J | 1 |
| Troch, M | 1 |
| Bourguignon, RP | 1 |
| Smets, P | 1 |
| Shinkai, T | 1 |
| Saijo, N | 1 |
| Sawamura, N | 1 |
| Funaki, U | 1 |
| Takahashi, S | 1 |
| Yokoyama, S | 1 |
| Fujita, J | 1 |
| Futami, H | 1 |
| Sasaki, Y | 1 |
| Shimizu, E | 1 |
| Critchley, P | 1 |
| Langdon, N | 1 |
| Parkes, JD | 1 |
| Quinn, NP | 1 |
| Shindler, JS | 1 |
| Marsden, CD | 1 |
| Lee, KY | 1 |
| Park, HJ | 1 |
| Chey, WY | 1 |
| Blancquaert, JP | 1 |
| Tanaka, T | 1 |
| Nakanishi, M | 1 |
| Hirose, Y | 1 |
| Mise, K | 1 |
| Matsushita, T | 1 |
| Yamaoto, T | 1 |
| Shirosaki, H | 1 |
| Tognoni, G | 1 |
| Franzosi, MG | 1 |
| Pampallona, S | 1 |
| Candido, A | 1 |
| Rossi, P | 1 |
| Tartaglione, R | 1 |
| Alfano, G | 1 |
| Menichella, G | 1 |
| Mango, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group, Prospective Study to Evaluate the Safety and Efficacy of Domperidone in 6-month-old to 12-year-old Pediatric Subjects With Nausea and Vomiting Due to Acute Gastroenteritis[NCT02699385] | Phase 3 | 10 participants (Actual) | Interventional | 2015-12-07 | Terminated (stopped due to Study prematurely terminated upon recommendation of IDMC due to lack of efficacy.) | ||
| Oral Ondansetron vs Domperidone for Symptomatic Treatment of Vomiting During Acute Gastroenteritis in Children: Multicentre Randomized Controlled Trial[NCT01257672] | Phase 3 | 356 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| An Investigational New Drug Program for the Use of Domperidone in the Treatment of Refractory Gastroesophageal Reflux Disease and Other Gastrointestinal Motility Disorders[NCT00777439] | 75 participants (Anticipated) | Interventional | 2008-10-31 | Recruiting | |||
| Oral Domperidone for Relief of Gastrointestinal Disorders in Patients Who Failed Standard Therapy[NCT00761254] | 42 participants (Actual) | Interventional | 2008-08-31 | Terminated (stopped due to PI withdrew due to increased responsibilities in clinical department.) | |||
| Does Domperidone, a D2-antagonist Alter Gastric Emptying Rates and Appetite Sensations in Healthy Adults?[NCT01347814] | 13 participants (Actual) | Interventional | 2008-02-29 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
24 reviews available for domperidone and Emesis
| Article | Year |
|---|---|
Drugs in Focus: Domperidone.
Topics: Antiemetics; Child; Domperidone; Gastrointestinal Agents; Gastrointestinal Diseases; Humans; Infant; | 2023 |
Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis.
Topics: Acute Disease; Antiemetics; Child; Child, Preschool; Dexamethasone; Diarrhea; Dimenhydrinate; Domper | 2020 |
[Cardiac adverse effects of domperidone in adult patients: a systematic review].
Topics: Adult; Antiemetics; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Domperidone; Female; Gastroesophag | 2015 |
Domperidone safety: a mini-review of the science of QT prolongation and clinical implications of recent global regulatory recommendations.
Topics: Antiemetics; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Death, Sudde | 2015 |
Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy.
Topics: Adult; Antiemetics; Antineoplastic Agents; Cannabinoids; Chlorpromazine; Dizziness; Domperidone; Eup | 2015 |
The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials.
Topics: Chi-Square Distribution; Critical Illness; Diarrhea; Domperidone; Dopamine Antagonists; Enteral Nutr | 2016 |
Nausea and vomiting in early pregnancy.
Topics: Acupressure; Administration, Oral; Domperidone; Female; Humans; Metoclopramide; Nausea; Phytotherapy | 2009 |
Question 2. How effective is domperidone at reducing symptoms of gastro-oesophageal reflux in infants?
Topics: Antiemetics; Domperidone; Evidence-Based Medicine; Gastroesophageal Reflux; Humans; Infant; Male; Pa | 2012 |
[Treatment of nausea and vomiting with prokinetics and neuroleptics in palliative care patients : a review].
Topics: Antiemetics; Antipsychotic Agents; Chronic Disease; Domperidone; Dopamine Antagonists; Drug Therapy, | 2012 |
Anti-emetics.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Humans; Metoclopramide; Migraine Disorders; Nausea; | 2001 |
Domperidone: review of pharmacology and clinical applications in gastroenterology.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting | 2007 |
Domperidone: review of pharmacology and clinical applications in gastroenterology.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting | 2007 |
Domperidone: review of pharmacology and clinical applications in gastroenterology.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting | 2007 |
Domperidone: review of pharmacology and clinical applications in gastroenterology.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting | 2007 |
Domperidone: review of pharmacology and clinical applications in gastroenterology.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting | 2007 |
Domperidone: review of pharmacology and clinical applications in gastroenterology.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting | 2007 |
Domperidone: review of pharmacology and clinical applications in gastroenterology.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting | 2007 |
Domperidone: review of pharmacology and clinical applications in gastroenterology.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting | 2007 |
Domperidone: review of pharmacology and clinical applications in gastroenterology.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Gastrointestinal Diseases; Humans; Nausea; Vomiting | 2007 |
Functional nausea and vomiting.
Topics: Acute Disease; Antidepressive Agents, Tricyclic; Antiemetics; Chronic Disease; Diagnosis, Differenti | 2007 |
Advances in anti-emetic therapy.
Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Clinical Trials as Topic; Dexamethasone; Do | 1984 |
Anaesthesia and emesis. II: Prevention and management.
Topics: Anesthesia; Antiemetics; Butyrophenones; Domperidone; Histamine H1 Antagonists; Humans; Metocloprami | 1984 |
Nausea and vomiting.
Topics: Analgesics; Anesthetics; Domperidone; Humans; Metoclopramide; Nausea; Phenothiazines; Piperazines; S | 1984 |
Dopamine antagonists in the upper gastrointestinal tract.
Topics: Diabetic Neuropathies; Digestive System; Domperidone; Dopamine Antagonists; Duodenum; Dyspepsia; Eso | 1984 |
Domperidone: a peripherally acting dopamine2-receptor antagonist.
Topics: Animals; Data Collection; Diabetes Mellitus; Domperidone; Dopamine Antagonists; Drug Interactions; G | 1999 |
Domperidone: a peripherally acting dopamine2-receptor antagonist.
Topics: Animals; Data Collection; Diabetes Mellitus; Domperidone; Dopamine Antagonists; Drug Interactions; G | 1999 |
Domperidone: a peripherally acting dopamine2-receptor antagonist.
Topics: Animals; Data Collection; Diabetes Mellitus; Domperidone; Dopamine Antagonists; Drug Interactions; G | 1999 |
Domperidone: a peripherally acting dopamine2-receptor antagonist.
Topics: Animals; Data Collection; Diabetes Mellitus; Domperidone; Dopamine Antagonists; Drug Interactions; G | 1999 |
Domperidone-induced acute dystonia and polycystic ovary syndrome.
Topics: Adolescent; Adult; Domperidone; Dyskinesia, Drug-Induced; Dystonia; Estrogens; Female; Humans; Nause | 1991 |
Domperidone.
Topics: Child; Child, Preschool; Domperidone; Gastric Emptying; Humans; Nausea; Vomiting | 1989 |
The control of cancer chemotherapy-induced nausea and vomiting.
Topics: Adrenal Cortex Hormones; Anti-Anxiety Agents; Antiemetics; Antineoplastic Agents; Antipsychotic Agen | 1985 |
[Recent advances in the management of chemotherapy-induced emesis].
Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Domperidone; Dronabinol; Drug Therapy, | 1986 |
Domperidone.
Topics: Colonic Diseases, Functional; Domperidone; Dyspepsia; Esophagitis, Peptic; Gastrointestinal Motility | 1988 |
Domperidone, a new dopamine antagonist.
Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; Dys | 1986 |
[The control of chemotherapy-induced nausea and vomiting].
Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Chlorpromazine; Cisplatin; Domperidone; Hum | 1985 |
38 trials available for domperidone and Emesis
| Article | Year |
|---|---|
Antiemetics improve the tolerance of polyethylene glycol for colonoscopy preparation: A randomized clinical trial.
Topics: Adult; Aged; Antiemetics; Cathartics; Colon; Colonoscopy; Domperidone; Female; Humans; Incidence; In | 2021 |
Safety and Efficacy of Low-dose Domperidone for Treating Nausea and Vomiting Due to Acute Gastroenteritis in Children.
Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Domperidone; Double-Blind | 2019 |
One-day versus two-day cleansing for colon capsule endoscopy: a prospective randomized pilot study.
Topics: Abdominal Pain; Adult; Aged; Bisacodyl; Capsule Endoscopy; Cathartics; Colon; Dietary Fiber; Domperi | 2014 |
Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial.
Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Domperidone; Double-Blind | 2016 |
Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Antidepressive Agents, Second-Generation; Antiemetics; Area | 2010 |
Domperidone versus cisapride in the treatment of infant regurgitation and increased acid gastro-oesophageal reflux: a pilot study.
Topics: Antiemetics; Cardiovascular System; Cisapride; Domperidone; Electrocardiography; Esophageal pH Monit | 2009 |
Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial.
Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Clinical Protocols; Dompe | 2011 |
Domperidone with ORT in the treatment of pediatric acute gastroenteritis in Japan: a multicenter, randomized controlled trial.
Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Domperidone; Drug Therapy | 2015 |
Advances in anti-emetic therapy.
Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Clinical Trials as Topic; Dexamethasone; Do | 1984 |
[Domperidone and metoclopramide in the prevention of postoperative nausea and vomiting].
Topics: Abortion, Induced; Adolescent; Adult; Clinical Trials as Topic; Domperidone; Double-Blind Method; Fe | 1983 |
Nausea and vomiting during spinal anaesthesia. Effect of metoclopramide and domperidone: a double-blind trial.
Topics: Aged; Anesthesia, Spinal; Blood Pressure; Clinical Trials as Topic; Domperidone; Double-Blind Method | 1984 |
[Clinical evaluation of antiemetics for vomiting due to cancer chemotherapy in children].
Topics: Adolescent; Antiemetics; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; D | 1982 |
Postoperative vomiting treated with domperidone. A double-blind comparison with metoclopramide and a placebo.
Topics: Adult; Aged; Antiemetics; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double-Blind Method | 1980 |
The efficacy of Domperidone (R 33812) in the treatment of postoperative vomiting. A double-blind study with a placebo.
Topics: Adolescent; Adult; Aged; Antiemetics; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double- | 1980 |
Double-blind evaluation of domperidone in acute vomiting and dyspeptic disorders.
Topics: Aged; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double-Blind Method; Dyspepsia; Female; | 1981 |
[Domperidone as an anti-emetic in antineoplastic chemotherapy].
Topics: Aged; Antineoplastic Agents; Benzimidazoles; Clinical Trials as Topic; Domperidone; Female; Gastroin | 1981 |
[The effect of domperidone in the prevention of nausea and vomiting during post-operative recovery period from anesthesia--a double blind study (author's transl)].
Topics: Adult; Anesthesia; Clinical Trials as Topic; Domperidone; Double-Blind Method; Female; Humans; Male; | 1981 |
[Domperidone after ether anaesthesia. Prevention of postoperative hyperemesis (author's transl)].
Topics: Adult; Aged; Anesthesia; Domperidone; Ether; Ethyl Ethers; Female; Humans; Male; Middle Aged; Postop | 1982 |
Bromocriptine and domperidone in the treatment of Parkinson disease.
Topics: Benzimidazoles; Bromocriptine; Domperidone; Female; Humans; Levodopa; Male; Middle Aged; Nausea; Par | 1981 |
Prophylaxis of delayed nausea and vomiting after cancer chemotherapy.
Topics: Adult; Aged; Chi-Square Distribution; Cisplatin; Domperidone; Double-Blind Method; Female; Humans; M | 1995 |
A randomised double blind crossover study of domperidone and prochlorperazine suppositories for controlling emesis in outpatients receiving chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Diarrhea; Domperidone; Double-Blind Method; Female; Humans; Male | 1994 |
[Clinical effects of granisetron and methylprednisolone against nausea, vomiting and anorexia induced by cisplatin].
Topics: Adult; Aged; Anorexia; Cisplatin; Domperidone; Drug Therapy, Combination; Female; Granisetron; Human | 1993 |
Neurobehavioral syndrome induced by H2-receptor blocker withdrawal: possible role of prolactin.
Topics: Adult; Anorexia; Antiemetics; Cimetidine; Domperidone; Female; Histamine H2 Antagonists; Humans; Mal | 1997 |
[Apomorphine for treatment of "off-periods" in Parkinson's disease].
Topics: Aged; Antiparkinson Agents; Apomorphine; Domperidone; Female; Humans; Injections, Subcutaneous; Levo | 1999 |
Domperidone (R 33 812) as an antiemetic in the treatment of postoperative vomiting. A double blind comparison between two different dosages (4 mg and 10 mg).
Topics: Adolescent; Adult; Aged; Antiemetics; Benzimidazoles; Clinical Trials as Topic; Domperidone; Double- | 1979 |
Evaluation of the antiemetic effect of domperidon in patients treated with cytostatic drugs.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Female; Humans | 1992 |
A comparison of controlled release metoclopramide and domperidone in the treatment of nausea and vomiting.
Topics: Delayed-Action Preparations; Domperidone; Double-Blind Method; Female; Humans; Male; Metoclopramide; | 1991 |
Comparison of starting antiemetic treatment 24 hours before or concurrently with cytotoxic chemotherapy.
Topics: Administration, Oral; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials a | 1989 |
Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery.
Topics: Abdomen; Adult; Antiemetics; Clinical Trials as Topic; Domperidone; Droperidol; Female; Humans; Hyst | 1986 |
Nabilone: an alternative antiemetic for cancer chemotherapy.
Topics: Adolescent; Antiemetics; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; D | 1986 |
Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Domperidone; Double-Blind Method; Dronabinol; Drug | 1986 |
Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as To | 1987 |
Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following gynaecological surgery in day cases.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Antiemetics; Clinical Trials as Topic; Dila | 1986 |
Buprenorphine versus domperidone in chemotherapy-induced emesis: a pilot study.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Buprenorphine; Clinical Trials as Topic; Domperidon | 1986 |
Domperidone, a new dopamine antagonist.
Topics: Administration, Oral; Adult; Child; Clinical Trials as Topic; Domperidone; Dopamine Antagonists; Dys | 1986 |
Domperidone antagonizes bromoergocriptine--induced nausea and vomiting without affecting its inhibition of prolactin secretion in puerperal women.
Topics: Adult; Bromocriptine; Domperidone; Drug Therapy, Combination; Female; Humans; Hyperprolactinemia; Na | 1987 |
The evaluation of domperidone and metoclopramide as antiemetics in day care abortion patients.
Topics: Abortion, Therapeutic; Adolescent; Adult; Anesthesia, General; Anesthesia, Obstetrical; Clinical Tri | 1985 |
High-dose alizapride versus high-dose domperidone: a double-blind comparative study in the management of cis-platinum-induced emesis.
Topics: Antiemetics; Cisplatin; Clinical Trials as Topic; Domperidone; Double-Blind Method; Female; Humans; | 1985 |
82 other studies available for domperidone and Emesis
| Article | Year |
|---|---|
Impact of Safety Warning on Domperidone Prescribing for Geriatric Patients in South Korea: Analysis of National Insurance Claim Data.
Topics: Aged; Antiemetics; Domperidone; Electrocardiography; Female; Heart Diseases; Humans; Male; Nausea; P | 2019 |
Prophylactic use of antiemetics for prevention of opioid-induced nausea and vomiting: a survey about Italian physicians' practice.
Topics: Adrenal Cortex Hormones; Adult; Analgesics, Opioid; Antiemetics; Antipsychotic Agents; Cross-Section | 2019 |
It Is Ok to Be Negative!
Topics: Child; Domperidone; Gastroenteritis; Humans; Nausea; Vomiting | 2019 |
Awareness of, and Compliance with, Domperidone Revised Labeling After a Risk-Minimization Activity in Europe.
Topics: Adult; Antiemetics; Arrhythmias, Cardiac; Cardiac Conduction System Disease; Cross-Sectional Studies | 2019 |
Moderate to severe nausea in radioactive iodine (RAI) therapy is associated with the RAI dose per body weight and was not prevented by ramosetron.
Topics: Adenoma; Adult; Aged; Antiemetics; Benzimidazoles; Domperidone; Dose-Response Relationship, Radiatio | 2014 |
Domperidone-induced dystonia: a rare and troublesome complication.
Topics: Adolescent; Antiemetics; Domperidone; Dystonia; Humans; Male; Vomiting | 2014 |
Does Braun enteroenterostomy reduce delayed gastric emptying after pancreaticoduodenectomy?
Topics: Abdominal Abscess; Acupuncture; Anastomotic Leak; Antiemetics; Domperidone; Enterostomy; Erythromyci | 2014 |
Drug treatment of adults with nausea and vomiting in primary care.
Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopra | 2014 |
Cardiovascular safety profile and clinical experience with high-dose domperidone therapy for nausea and vomiting.
Topics: Adult; Cardiotoxicity; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Mon | 2015 |
Prophylactic Use of Antiemetics for Prevention of Opioid-Induced Nausea and Vomiting: A Questionnaire Survey among Japanese Physicians.
Topics: Analgesics, Opioid; Antiemetics; Benzodiazepines; Chemoprevention; Domperidone; Health Care Surveys; | 2015 |
Domperidone to Treat Symptoms of Gastroparesis: Benefits and Side Effects from a Large Single-Center Cohort.
Topics: Adult; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Diarrhea; Domperidone; Dopamine An | 2016 |
Domperidone and sudden death. Cardiac rhythm disorders: QT interval prolongation.
Topics: Antiemetics; Arrhythmias, Cardiac; Canada; Death, Sudden, Cardiac; Domperidone; Humans; Long QT Synd | 2008 |
[Efficacy of preventive treatment for delayed emesis induced by FOLFOX4 chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dexamethasone; Do | 2009 |
Tolerance to enteral nutrition therapy in traumatic brain injury patients.
Topics: Adult; Aged; Antiemetics; Brain Injuries; Cross-Sectional Studies; Domperidone; Enteral Nutrition; E | 2012 |
Case series: paradoxical action of domperidone leads to increased vomiting.
Topics: Child; Child, Preschool; Domperidone; Enteral Nutrition; Female; Humans; Infant; Male; Vomiting | 2013 |
Case report--the 46 year old man with a 5 month history of vomiting.
Topics: Antiemetics; Diabetes Mellitus, Type 2; Diagnosis, Differential; Domperidone; Gastroparesis; Humans; | 2011 |
Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma; Domperidone; Dose Fractionation, Radiatio | 2002 |
Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew).
Topics: Animals; Antiemetics; Butanols; Capsaicin; Cyclooxygenase Inhibitors; Dihydroergotamine; Diphenhydra | 2005 |
Differential action of domperidone to modify emesis and behaviour induced by apomorphine in the ferret.
Topics: Animals; Antiemetics; Antiparkinson Agents; Apomorphine; Behavior, Animal; Domperidone; Ferrets; Hab | 2005 |
Antiemetics for children with gastroenteritis: off-label but still on in clinical practice.
Topics: Acute Disease; Administration, Rectal; Antiemetics; Child, Preschool; Domperidone; Gastroenteritis; | 2006 |
Dosage and drug interactions of domperidone.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Drug Interactions; Drug Labeling; Gastrointestinal D | 2008 |
Extrapyramidal reactions due to domperidone.
Topics: Adult; Antiemetics; Basal Ganglia Diseases; Benzimidazoles; Domperidone; Female; Humans; Infant; Mal | 1980 |
Sudden death in cancer patient on high-dose domperidone.
Topics: Aged; Carcinoma, Squamous Cell; Death, Sudden; Domperidone; Esophageal Neoplasms; Humans; Male; Vomi | 1982 |
Gynecomastia in a male infant given domperidone.
Topics: Domperidone; Female; Galactorrhea; Gynecomastia; Humans; Infant; Male; Pregnancy; Vomiting | 1982 |
Refusal of further cancer chemotherapy due to antiemetic drug.
Topics: Antineoplastic Agents; Child; Domperidone; Drug Therapy, Combination; Dystonia; Female; Humans; Pati | 1984 |
Two sudden deaths during prophylactic antiemetic treatment with high doses of domperidone and methylprednisolone.
Topics: Cisplatin; Death, Sudden; Domperidone; Drug Therapy, Combination; Humans; Methylprednisolone; Middle | 1984 |
[Metadoxine in the treatment of vomiting in uremic patients under dialysis treatment].
Topics: Adolescent; Adult; Aged; Domperidone; Drug Combinations; Humans; Middle Aged; Pyridoxine; Pyrrolidin | 1984 |
[Pharmacotherapy of emesis caused by cytostatic agents].
Topics: Antiemetics; Antineoplastic Agents; Domperidone; Dronabinol; Humans; Metoclopramide; Phenothiazines; | 1982 |
Increased vomiting induced by an antiemetic drug.
Topics: Alginates; Aluminum Hydroxide; Antacids; Bezoars; Bicarbonates; Domperidone; Drug Combinations; Huma | 1984 |
Altered gastric emptying and prevention of radiation-induced vomiting in dogs.
Topics: Animals; Cobalt Radioisotopes; Dogs; Domperidone; Gastric Emptying; Male; Radiation Injuries, Experi | 1984 |
Seizures after antiemetic treatment with high dose domperidone: report of four cases.
Topics: Adult; Blood Glucose; Calcium; Cisplatin; Domperidone; Epilepsy, Tonic-Clonic; Humans; Magnesium; Po | 1984 |
Cardiac arrest after treatment with intravenous domperidone.
Topics: Adult; Domperidone; Female; Heart Arrest; Humans; Middle Aged; Nausea; Vomiting | 1984 |
[Domperidone suppositories treatment for nausea and vomiting during cancer chemotherapy].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Domperidone; Female; Humans; Male; Middle Aged; Naus | 1984 |
[Effects of domperidone suppository against adverse reactions in digestive organs induced by cancer chemotherapy].
Topics: Adult; Aged; Anorexia; Antineoplastic Agents; Domperidone; Female; Hodgkin Disease; Humans; Leukemia | 1984 |
[Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine].
Topics: Adult; Aged; Antineoplastic Agents; Chlorpromazine; Domperidone; Female; Humans; Male; Middle Aged; | 1983 |
Alleviation of chemotherapy induced emesis by oral lorazepam and domperidone.
Topics: Adult; Antineoplastic Agents; Domperidone; Drug Therapy, Combination; Female; Humans; Lorazepam; Mal | 1983 |
[Domperidone (Motilium)].
Topics: Adolescent; Adult; Domperidone; Humans; Vomiting | 1982 |
[Pharmacotherapy of emesis resulting from cytostatic agents].
Topics: Adult; Antineoplastic Agents; Domperidone; Dystonia; Female; Humans; Vomiting | 1982 |
[Nausea and vomiting: pharmacologic aspects].
Topics: Animals; Antiemetics; Dogs; Domperidone; Humans; Nausea; Receptors, Dopamine; Vomiting | 1982 |
[Domperidon--a new gastrokinetic and anti-emetic without central-nervous side effects].
Topics: Acetylcholine; Acetylcholinesterase; Antiemetics; Benzimidazoles; Domperidone; Dyspepsia; Enzyme Inh | 1980 |
The effects of orally administered Y-25130, a selective serotonin3-receptor antagonist, on chemotherapeutic agent-induced emesis.
Topics: Administration, Oral; Animals; Antiemetics; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, He | 1993 |
[Prokinetic drugs in digestive disorders].
Topics: Antineoplastic Agents; Cisapride; Domperidone; Esophageal Motility Disorders; Gastroesophageal Reflu | 1993 |
Pica in rats is analogous to emesis: an animal model in emesis research.
Topics: Animals; Antiemetics; Apomorphine; Cisplatin; Copper; Copper Sulfate; Disease Models, Animal; Domper | 1993 |
Gastroprokinetic effect of a new benzamide derivative itopride and its action mechanisms in conscious dogs.
Topics: Animals; Antiemetics; Apomorphine; Benzamides; Benzyl Compounds; Dogs; Domperidone; Dopamine Antagon | 1996 |
The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis.
Topics: Abdominal Pain; Administration, Oral; Adult; Aged; Antiemetics; Domperidone; Dopamine Antagonists; E | 1997 |
[Multi-drug antiemetic treatment and effect of treatment duration of concurrent steroids--for complete control of chemotherapy-induced nausea/vomiting in gynecological cancer].
Topics: Administration, Oral; Adult; Aged; Anti-Anxiety Agents; Antiemetics; Antineoplastic Combined Chemoth | 1997 |
Radiation-induced emesis: a prospective observational multicenter Italian trial. The Italian Group for Antiemetic Research in Radiotherapy.
Topics: Adult; Antiemetics; Domperidone; Drug Administration Schedule; Female; Humans; Incidence; Indoles; M | 1999 |
Gastric relaxation by morphine, apomorphine and fentanyl in the conscious dog.
Topics: Animals; Apomorphine; Benzimidazoles; Dogs; Domperidone; Fentanyl; Haloperidol; Morphine; Muscle Con | 1979 |
The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors.
Topics: Animals; Behavior, Animal; Cerebral Ventricles; Domperidone; Female; Fenclonine; Ferrets; Loperamide | 1992 |
Some possible gynaecological indications for peripheral antidopamine therapy.
Topics: Adult; Climacteric; Domperidone; Drug Evaluation; Dyspepsia; Female; Gastrointestinal Diseases; Huma | 1992 |
The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Dimenhydrinate; Domperidone; Femal | 1990 |
Functional localization of specific receptors mediating gastrointestinal motor correlates of vomiting.
Topics: Animals; Apomorphine; Atropine; Copper; Copper Sulfate; Digestive System; Dogs; Domperidone; Female; | 1989 |
Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Cat Diseases; Cats; Ch | 1989 |
Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting.
Topics: Adolescent; Adult; Aged; Domperidone; Dyspepsia; Female; Genital Diseases, Female; Humans; Hyperemes | 1989 |
Cardiotoxicity of intravenous domperidone.
Topics: Arrhythmias, Cardiac; Domperidone; Female; Humans; Infusions, Parenteral; Vomiting | 1985 |
Effects of dopamine receptor antagonists on gastrin and vomiting responses to apomorphine.
Topics: Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Dogs; Domperidone; Female; Gastrins; Male; | 1987 |
Continuous ECG monitoring of children with cancer receiving domperidone.
Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Child | 1986 |
Effect of ionizing radiation on gastric secretion and gastric motility in monkeys.
Topics: Animals; beta-Endorphin; Domperidone; Electrophysiology; Endorphins; Fasting; Gastric Emptying; Gast | 1985 |
Mechanisms of radiation-induced emesis in the dog.
Topics: Animals; Dogs; Domperidone; Electrophysiology; Female; Indomethacin; Male; Radiation Injuries, Exper | 1988 |
Use of Motilium in the perioperative period from the aspect of the anaesthesiologist.
Topics: Adolescent; Adult; Domperidone; Female; Humans; Middle Aged; Nausea; Preanesthetic Medication; Vomit | 1988 |
Domperidone: an alternative to metoclopramide.
Topics: Acute Disease; Adolescent; Adult; Child; Domperidone; Humans; Metoclopramide; Nausea; Vomiting | 1988 |
Domperidone.
Topics: Domperidone; Humans; Nausea; Vomiting | 1988 |
Effect of domperidone on postoperative vomiting and dyspepsia aggravated by operation.
Topics: Adult; Domperidone; Dyspepsia; Female; Humans; Middle Aged; Nausea; Postoperative Complications; Pre | 1988 |
Use of Motilium with gastrokinetic and anti-emetic action in outpatients.
Topics: Adult; Ambulatory Care; Domperidone; Female; Gastrointestinal Motility; Humans; Hungary; Male; Middl | 1988 |
[Emetic and catalepsy-inducing actions of buflomedil].
Topics: Administration, Oral; Animals; Bromocriptine; Catalepsy; Dogs; Domperidone; Dose-Response Relationsh | 1988 |
Dopamine antagonist domperidone (Motilium) in everyday clinical practice.
Topics: Adult; Aged; Domperidone; Dyspepsia; Female; Humans; Male; Middle Aged; Nausea; Vomiting | 1988 |
Evidence that 5-hydroxytryptamine3 receptors mediate cytotoxic drug and radiation-evoked emesis.
Topics: Animals; Antineoplastic Agents; Apomorphine; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Ci | 1987 |
[Use of estrogens in post-coital contraception. Our case material of 243 cases].
Topics: Adolescent; Adult; Contraceptives, Postcoital; Contraceptives, Postcoital, Hormonal; Domperidone; Es | 1988 |
Characterization of radiation-induced emesis in the ferret.
Topics: Animals; Apomorphine; Carnivora; Cobalt Radioisotopes; Domperidone; Emetics; Ferrets; Gamma Rays; Ma | 1988 |
Observations with dopamine antagonist domperidone (Motilium) in controlling postoperative dyspepsias and vomiting.
Topics: Abdomen; Adult; Aged; Domperidone; Dyspepsia; Female; Humans; Male; Middle Aged; Postoperative Compl | 1987 |
Evaluation of domperidone as a modifier of gamma-radiation-induced emesis.
Topics: Animals; Antiemetics; Cimetidine; Cobalt Radioisotopes; Dexamethasone; Dogs; Domperidone; Drug Thera | 1987 |
[Acute dystonic reaction due to domperidone in a infant].
Topics: Domperidone; Dystonia; Humans; Infant; Male; Vomiting | 1986 |
[Clinical evaluation of sulpiride against nausea and vomiting during cancer chemotherapy compared with domperidone--envelope method].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Drug Evaluation; Female; H | 1986 |
Radiation-induced emesis in the dog: effects of lesions and drugs.
Topics: Animals; Apomorphine; Cerebral Ventricles; Dogs; Domperidone; Indomethacin; Neurons; Prostaglandins; | 1986 |
Extrapyramidal dysfunction after domperidone.
Topics: Basal Ganglia Diseases; Domperidone; Humans; Infant; Male; Vomiting | 1985 |
Domperidone.
Topics: Domperidone; Humans; Parkinson Disease; Vomiting | 1985 |
Studies on mechanism of retching and vomiting in dogs. Effect of peripheral dopamine blocker on myoelectric changes in antrum and upper small intestine.
Topics: Animals; Copper; Copper Sulfate; Dogs; Domperidone; Dopamine; Duodenum; Electrophysiology; Jejunum; | 1985 |
Influence of peripheral and central administration of apomorphine and morphine on intragastric pressure in the dog.
Topics: Animals; Apomorphine; Brain; Chemoreceptor Cells; Dogs; Domperidone; Female; Injections, Intravenous | 1985 |
[Effect of combined use of adrenocortical hormones and domperidone as anti-emetics during cisplatin therapy].
Topics: Adult; Aged; Breast Neoplasms; Cisplatin; Domperidone; Drug Therapy, Combination; Esophageal Neoplas | 1985 |
A pilot study of high-dose domperidone as an antiemetic in patients treated with cisplatin.
Topics: Adolescent; Adult; Aged; Cisplatin; Domperidone; Female; Humans; Infusions, Parenteral; Male; Middle | 1985 |
Review of the current status of prokinetic agents in gastroenterology.
Topics: Benzamides; Chemical Phenomena; Chemistry; Cisapride; Dexamethasone; Digestive System; Domperidone; | 1985 |
Sequential therapy with lithium in chemotherapy-induced vomiting.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Domperidone; Drug Evaluatio | 1985 |