Page last updated: 2024-10-26

domperidone and Drooling

domperidone has been researched along with Drooling in 1 studies

Domperidone: A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
domperidone : 1-[3-(Piperidin-1-yl)propyl]-1,3-dihydro-2H-benzimidazol-2-one in which the 4-position of the piperidine ring is substituted by a 5-chloro-1,3-dihydro-2H-benzimidazol-2-on-1-yl group. A dopamine antagonist, it is used as an antiemetic for the short-term treatment of nausea and vomiting, and to control gastrointestinal effects of dopaminergic drugs given in the management of parkinsonism. The free base is used in oral suspensions, while the maleate salt is used in tablet preparations.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with domperidone (1 or 2 mg/kg body weight) or the ablation of the area postrema (AP) abolished the gastric motor response and salivary secretion induced by the administration of apomorphine."1.32Area postrema mediates gastric motor response induced by apomorphine in rats. ( Kobashi, M; Koga, T; Matsuo, R; Mizutani, M; Tsukamoto, G, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koga, T1
Kobashi, M1
Mizutani, M1
Tsukamoto, G1
Matsuo, R1

Other Studies

1 other study available for domperidone and Drooling

ArticleYear
Area postrema mediates gastric motor response induced by apomorphine in rats.
    Brain research, 2003, Jan-17, Volume: 960, Issue:1-2

    Topics: Animals; Apomorphine; Area Postrema; Autonomic Nervous System; Domperidone; Dopamine Antagonists; Do

2003